Diagnostic anti-Bovine viral diarrhea virus (BVDV) gp53 antibodies pairs for animal health (animal infectious disease) testing in ELISA, Lateral flow immunoassay (LFIA) and other immunoassays
Catalog Number: GMP-AD-Ruminants-15Ab
Definition of the disease: Monoclonal antibodies reactive to the bovine viral diarrhea virus (BVDV) protein gp53 were produced and characterized. These antibodies and our panel of anti-p80/125 monoclonal antibodies were tested for their cross-reactivity with 11 different North American and European (Danish) BVDV strains and isolates including viruses of both cytopathic and noncytopathic biotypes. The four anti-gp53 monoclonal antibodies were neutralizing for the homologous Danish cytopathic isolate and cross-reacted with all BVDV strains examined except for the Draper strain. Further, anti-gp53 monoclonal antibodies neutralized the majority of BVDV strains examined. The anti-p80/125 monoclonal antibodies cross-reacted with all eleven strains and isolates tested. This indicated that various strains of BVDV have common epitopes. The broad cross-reactivities demonstrated by these monoclonal antibodies suggest that a pool of these antibodies may be used for detection of BVDV cellular contamination or for virus isolation, in place of polyclonal antiserum.
Genemedi produces core animal health diagnostic ingredients-validated antibodies pairs Mouse anti-Bovine viral diarrhea virus (BVDV) gp53 monoclonal antibody and antigens for rapid test kit of animal infectious disease with Bovine viral diarrhea virus (BVDV) gp53 to evaluate the animal health of Ruminants.
The paired antibodies are both monoclonal antibody(mab).
All the antibodies and antiges of animal disease test are suitable for in functional ELISA, and other immunoassays in diagnostics. The antibody can act as a capture antibody and detection antibody. Antigens are validated as positive control materials.
Delivery impact due to the Coronavirus Outbreak
With the COVID-19 outbreak in the world, many flights have been cancelled. In order for the customer to receive the goods properly, we use the FedEx Customized Freight (FCF) of Fedex which demands a higher fee. If the delivery fee is more expensive in your area, we will contact you by mail.
(1~4, 4 antibodies in pairs)
|Size||Price(In USD)||Qty (Quantity)||Sum(In USD)|
|Antigens||Bovine viral diarrhea virus (BVDV) gp53|
|Antibody||Mouse anti-Bovine viral diarrhea virus (BVDV) gp53 monoclonal antibody|
|Bioactivity validation||Antibody Binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays inBovine viral diarrhea virus (BVDV) gp53 level test and Ruminants-diagnositcs.|
|Antigen description||Bovine viral diarrhea virus (BVDV) is a significant pathogen associated with gastrointestinal, respiratory, and reproductive diseases of cattle worldwide. It causes continuous economic losses to the cattle industry primarily due to decreased reproductive performance. The ability of virus to cross the placenta during early pregnancy can result in the birth of persistently infected (PI) calves. Persistently infected animals are generally much more efficient transmitters of BVDV than transiently or acutely infected animals because they are capable of shedding large quantities of virus throughout their lives and are considered the primary reservoirs for BVDV. Due to the nature of viral infections, there is no treatment to fully cure an animal of a viral infection. All control programs which are in use in many countries of the world, mainly depend upon the detection of PI animals, eliminating them and preventing their return into the herds. Detection of PI animals at early stage, particularly soon after birth is of significant benefit to implement BVDV control programs. Available diagnostic tests such as virus isolation (VI), immunohistochemistry (IHC), Antigen-Capture ELISA (ACE), and reverse transcriptase polymerase chain reaction (RT-PCR) are used for detection of PI cattle. Each method to detect BVDV has advantages, disadvantages, and applicability for different diagnostic situations. The reliability of diagnostic tests is optimized by choosing the appropriate sampling strategy on the basis of animal age.|
|Purity||Purity: ≥95% (SDS-PAGE)|
|Application||Paired antibody immunoassay validation in sandwich Elisa, Lateral flow immunoassay (LFIA), and other immunoassays;|
|Formulation||Supplied as a 0.2 μM filtered solution of PBS, PH7.4.|
|Storage||Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.|