Canine ACE2/hFc antibody and antigen (recombinant protein)

Diagnostic anti-Canine ACE2/hFc antibodies pairs and antigen for animal health (animal Dog/Canine acute respiratory distress syndrome) testing in ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA and POCT

Target products collectionGo to Companion Animal disease testing products collection >>


Product information

Catalog No.DescriptionUS $ Price (per mg)
GMP-CAN-ACE2/hFc-Ag01Canine ACE2/hFc$3090.00
GMP-CAN-ACE2/hFc-Ab01Anti-Canine ACE2/hFc mouse monoclonal antibody (mAb)$3090.00
GMP-CAN-ACE2/hFc-Ab02Anti-Canine ACE2/hFc mouse monoclonal antibody (mAb)$3090.00
GMP-CAN-ACE2/hFc-Ab03Anti-Canine ACE2/hFc human monoclonal antibody (mAb)$3090.00
GMP-CAN-ACE2/hFc-Ab04Anti-Canine ACE2/hFc human monoclonal antibody (mAb)$3090.00

Size： 1mg | 10mg | 100mg



Product Description

Cat No. GMP-CAN-ACE2/hFc-Ag01
Product NameCanine ACE2/hFc
Target/BiomarkerCanine ACE2/hFc
Expression platformE.coli
IsotypesRecombinant Antigen
Bioactivity validationAnti-Canine ACE2/hFc antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in ACE2/hFc level test of animal Dog/Canine with acute respiratory distress syndrome.
TagHis
Reconized/Reactive SpecicsCanine ACE2/hFc
Product descriptionRecombinant Canine ACE2/hFc protein was expressed in E.coli - based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus.
PurityPurity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
FormulationLyophilized from sterile PBS, PH 7.4
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Cat No.GMP-CAN-ACE2/hFc-Ab01,GMP-CAN-ACE2/hFc-Ab02
Target/BiomarkerCanine ACE2/hFc
Product NameAnti-Canine ACE2/hFc mouse monoclonal antibody (mAb)
Expression platformCHO
Isotypes Mouse IgG
Bioactivity validationRecombinant Canine ACE2/hFc antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Canine ACE2/hFc antibodies in Canine ACE2/hFc level test of animal Dog/Canine with acute respiratory distress syndrome.
Product descriptionAnti-Canine ACE2/hFc mouse monoclonal antibody (mAb) is a mouse monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Canine ACE2/hFc antibodies.
PurityPurity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
FormulationLyophilized from sterile PBS, PH 7.4
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Cat No.GMP-CAN-ACE2/hFc-Ab03,GMP-CAN-ACE2/hFc-Ab04
Target/BiomarkerCanine ACE2/hFc
Product NameAnti-Canine ACE2/hFc human monoclonal antibody (mAb)
Expression platformCHO
IsotypesHuman lgG1
Bioactivity validationRecombinant Canine ACE2/hFc antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Canine ACE2/hFc antibodies in Canine ACE2/hFc level test of animal Dog/Canine with acute respiratory distress syndrome.
Product descriptionAnti-Canine ACE2/hFc mouse monoclonal antibody (mAb) is a human monoclonal antibody produced by CHO. The antibody is ELISA validated as capture antibody and detection antibody pair.
PurityPurity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
FormulationLyophilized from sterile PBS, PH 7.4
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Reference




    Validation Data


    Click to get more Data / Case study about the product.



    Target/Biomarker Information


    Canine ACE2/hFc, a fusion protein at the intersection of canine physiology and molecular research, emerges as an instrument of remarkable significance. Its composite nature comprises two distinct components: Canine ACE2 (Angiotensin-Converting Enzyme 2) and the human immunoglobulin Fc region (hFc). Together, they offer a multidimensional lens through which to examine the physiology of dogs and their susceptibility to zoonotic diseases.

    Canine ACE2, the foundational element of this fusion protein, is an integral component of the Renin-Angiotensin System (RAS) in dogs. As a membrane-bound metallopeptidase, it wields substantial influence over the regulation of blood pressure, fluid balance, and cardiovascular homeostasis. Canine ACE2 achieves this by catalyzing the conversion of Angiotensin II, a potent vasoconstrictor, into Angiotensin 1-7, a vasodilator. This enzymatic equilibrium serves as a fulcrum in the intricate dance of canine cardiovascular physiology.

    The "hFc" component, on the other hand, adds an intriguing layer of utility to Canine ACE2/hFc. This fusion with the human immunoglobulin Fc region amplifies the protein's versatility in laboratory settings. It endows researchers with the capacity to efficiently detect, purify, and manipulate the protein, thus facilitating a deeper dive into the realms of canine molecular biology.

    One of the most notable aspects of Canine ACE2/hFc is its relevance in zoonotic research. The fusion protein serves as a key tool for investigating the interactions between canine ACE2 receptors and various pathogens, with a particular focus on coronaviruses. This is of profound significance in light of zoonotic diseases like SARS-CoV-2, where the susceptibility of dogs to infection has raised critical questions about transmission dynamics and preventive strategies.



    About GDU


    GDU

    GDU helps global diagnostic partners in high quality of raw material discovery, development, and application. GDU believes in Protein&antibody Innovation for more reliable diagnostic solutions.