Feline ACE2/hFc antibody and antigen (recombinant protein) GMP-FEL-ACE2-hFc

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Product information

Size： 1mg | 10mg | 100mg

Catalog No.	Description	US $ Price (per mg)	First Order Discount	First Order Discount Price
GMP-FEL-ACE2/hFc-Ag01	Recombinant Feline ACE2/hFc protein	3090
GMP-FEL-ACE2/hFc-Ab01	Anti-Feline ACE2/hFc mouse monoclonal antibody (mAb)	1953	20%	1562.4
GMP-FEL-ACE2/hFc-Ab02	Anti-Feline ACE2/hFc mouse monoclonal antibody (mAb)	1953	20%	1562.4
GMP-FEL-ACE2/hFc-Ab03	Anti-Feline ACE2/hFc mouse monoclonal antibody (mAb)	1953	20%	1562.4
GMP-FEL-ACE2/hFc-Ab04	Anti-Feline ACE2/hFc mouse monoclonal antibody (mAb)	1953	20%	1562.4

Shipping Costs: $360–$760
Antibodies: $360 Antigens: $760 (Elevated cost due to antigen heterogeneity, post-translational modifications, structural complexity, and specialized handling.)

Product Description

Cat No. of Products	GMP-FEL-ACE2/hFc-Ag01
Product Name	Recombinant Feline ACE2/hFc protein
Target/Biomarker	Feline Angiotensin Converting Enzyme 2 (ACE2/hFc)
Expression platform	E.coli
Isotypes	Recombinant Antigen
Bioactivity validation	Anti-Feline Angiotensin Converting Enzyme 2 antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in ACE2/hFc level test of animal Cat/Feline with acute respiratory distress syndrome.
Tag	His
Products description	Recombinant Feline ACE2/hFc protein was expressed in E.coli - based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution	PBS liquid / Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No. of Products	GMP-FEL-ACE2/hFc-Ab01, GMP-FEL-ACE2/hFc-Ab02, GMP-FEL-ACE2/hFc-Ab03, GMP-FEL-ACE2/hFc-Ab04
Product Name	Anti-Feline ACE2/hFc mouse monoclonal antibody (mAb)
Target/Biomarker	Feline Angiotensin Converting Enzyme 2 (ACE2/hFc)
Expression platform	CHO
Isotypes	Mouse IgG
Bioactivity validation	Anti-Feline Angiotensin Converting Enzyme 2 antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in ACE2/hFc level test of animal Cat/Feline with acute respiratory distress syndrome.
Tag	mFc
Products description	Anti-Feline ACE2/hFc mouse monoclonal antibody (mAb) was expressed in CHO - based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference

Validation Data

Click to get more Data / Case study about the product.

Target/Biomarker information

Feline ACE2/hFc, a fusion protein at the crossroads of feline biology and molecular research, stands as a testament to scientific innovation. Its composite nature combines two distinct components: Feline ACE2 (Angiotensin-Converting Enzyme 2) and the human immunoglobulin Fc region (hFc). Together, they offer a multifaceted approach to dissecting feline cardiovascular physiology and understanding the feline-human interface in the context of zoonotic diseases. Feline ACE2, the foundational element of this fusion protein, is an indispensable player in the Renin-Angiotensin System (RAS) of cats. As a membrane-bound metallopeptidase, it governs the conversion of Angiotensin II to Angiotensin 1-7, a critical transformation that exerts profound influence over blood pressure, fluid balance, and overall cardiovascular equilibrium in felines. Measuring Feline ACE2/hFc provides researchers with an unparalleled opportunity to explore the intricacies of this enzymatic equilibrium, unravelling the molecular secrets that underpin feline cardiovascular health. The fusion with the human immunoglobulin Fc region (hFc) is a stroke of scientific ingenuity. It elevates Feline ACE2/hFc beyond the confines of traditional research tools, rendering it amenable to precise detection, purification, and manipulation in laboratory settings. This innovation opens doors to in-depth investigations into feline ACE2 receptor biology, enabling researchers to dissect molecular mechanisms with surgical precision. Beyond its utility in understanding feline physiology, Feline ACE2/hFc assumes a central role in zoonotic research. With the global spotlight on zoonotic diseases, particularly exemplified by the COVID-19 pandemic, the fusion protein provides a unique lens through which to examine the potential role of cats as reservoirs and vectors for such diseases. Researchers can utilize Feline ACE2/hFc to probe interactions between feline ACE2 receptors and pathogens like coronaviruses, shedding light on susceptibility, transmission dynamics, and the development of preventive strategies.

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