Bovine serum albumin(BSA) antibody/antigen (BSA/OVA/KLH conjugated hapten)

 Download 

anti-Bovine serum albumin(BSA) antibody and Carrier-coupled antigen/immunogen (hapten-carrier conjugates)

Go to Allergen diagnostics products collection >>

Product information

Size： 1mg | 10mg | 100mg

Product Description

BSA-Bovine serum albumin(BSA)

OVA-Bovine serum albumin(BSA)

Anti-Bovine serum albumin(BSA) mouse monoclonal antibody

Anti-Bovine serum albumin(BSA) human monoclonal antibody

Reference

Validation Data

Click to get more Data / Case study about the product.

Biomarker Information

. Bovine Serum Albumin (BSA) in Allergen Research:

Bovine Serum Albumin (BSA), identified by serial number #1, plays a pivotal role in the realm of allergen research as a versatile and indispensable component. BSA is a globular protein extracted from the serum of cows, and its significance stems from its remarkable ability to enhance the immunogenicity of small molecules or haptens, which may inherently lack immunogenic properties.

In allergen research, one of the primary challenges lies in studying and understanding immune responses to specific allergens. Many allergenic molecules, or haptens, are small in size and may not be immunogenic on their own. This is where BSA steps in as a critical facilitator. When allergenic molecules are chemically coupled or conjugated with BSA, they undergo a transformation – they become more immunogenic, thereby becoming recognizable by the immune system. BSA serves as a stable carrier for presenting these modified antigens to the immune system, thereby promoting the generation of antibodies and eliciting immune responses.

The process of coupling allergenic molecules to BSA enhances the molecule's antigenicity, allowing researchers to investigate immune reactions with precision and accuracy. This is particularly valuable in allergen research, where understanding the immune response to specific allergens is crucial for diagnostics, therapeutics, and vaccine development.

2. Importance of Measuring Bovine Serum Albumin (BSA):

The measurement of Bovine Serum Albumin (BSA), denoted by serial number #2, holds paramount importance in scientific endeavors across various disciplines, and it extends far beyond allergen research. Here, we delve into the multifaceted reasons why accurate measurement of BSA concentration is indispensable:

a. Quality Assurance:

BSA is frequently employed as a standard or reference protein in laboratory assays, with protein quantification methodologies like the Bradford or BCA assay being notable examples. These assays rely on the accurate quantification of BSA concentration to ensure the reliability and consistency of experimental outcomes. Precise measurement of BSA concentration is, therefore, a fundamental step in quality control, allowing researchers to validate the accuracy of their assays.

b. Standardization:

In immunoassays, such as enzyme-linked immunosorbent assays (ELISAs), BSA serves as a gold standard for calibrating assays and determining the exact concentration of target molecules. By using BSA with meticulously measured concentrations as standards, researchers can obtain highly reliable quantitative data. This standardization not only enhances the precision of experiments but also facilitates comparisons across different studies and laboratories, fostering scientific reproducibility and consistency.

c. Validation in Research:

In research involving BSA-conjugated small molecules or antigens, quantifying BSA concentration within the conjugate is imperative. This measurement ensures the accuracy of antigen concentration determination and validates the success of the conjugation process. Accurate BSA quantification instills confidence in researchers, assuring them that the carrier molecule's concentration does not adversely affect the experimental outcomes. In the context of allergen research, where BSA-conjugated allergens are frequently employed, this step is particularly crucial for robust and credible results.

d. Experimental Control:

In the domain of allergen research and beyond, precise control of experimental conditions is essential. When BSA is used as a carrier for creating BSA-conjugated antigens, quantifying BSA levels allows researchers to finely regulate and adjust BSA concentrations in experiments. This control minimizes the risk of BSA interfering with immune responses and ensures the integrity of research results. In allergen studies, maintaining the correct BSA concentration within BSA-conjugated allergens is vital to accurately decipher the immune system's response to specific allergens.

In summary, the measurement of Bovine Serum Albumin (BSA) is an integral component of scientific practices across diverse disciplines. It serves as the linchpin for quality assurance, standardization, research validation, and meticulous control of experimental conditions. This extends from fundamental laboratory assays to advanced applications like allergen research and immunology studies. Accurate BSA quantification not only ensures the reliability and robustness of experimental results but also contributes to the overall advancement of scientific knowledge and innovation.

About GDU