Aflatoxin B1(B1) antibody/antigen (BSA/OVA/KLH conjugated hapten)

anti-Aflatoxin B1(B1) antibody and Carrier-coupled antigen/immunogen (hapten-carrier conjugates)

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Product information

Catalog No.DescriptionUS $ Price (per mg)
GMP-SMT-144-11. BSA-Aflatoxin B1(B1)
2. Anti-Aflatoxin B1(B1) mouse monoclonal antibody
$2709.00
GMP-SMT-144-21. OVA-Aflatoxin B1(B1)
2. Anti-Aflatoxin B1(B1) mouse monoclonal antibody
$2709.00
GMP-SMT-144-31. BSA-Aflatoxin B1(B1)
2. Anti-Aflatoxin B1(B1) human monoclonal antibody
$2709.00
GMP-SMT-144-41. OVA-Aflatoxin B1(B1)
2. Anti-Aflatoxin B1(B1) human monoclonal antibody
$2709.00
GMP-SMT-144-Ag-1BSA-Aflatoxin B1(B1)$756.00
GMP-SMT-144-Ag-2OVA-Aflatoxin B1(B1)$756.00
GMP-SMT-144-Ab-1Anti-Aflatoxin B1(B1) mouse monoclonal antibody$1953.00
GMP-SMT-144-Ab-2Anti-Aflatoxin B1(B1) human monoclonal antibody$1953.00

Size: 1mg | 10mg | 100mg



Product Description


BSA-Aflatoxin B1(B1)

Cat No.GMP-SMT-144-Ag-1
Bioactivity validationCompetitive immunoassay validation (Competitive ELISA) with hapten-carrier conjugates and anti-Hapten antibody;
Products descriptionCompetitive immunoassay-validated hapten-carrier conjugates BSA-Aflatoxin B1(B1) with anti-Hapten antibody. The hapten hapten-carrier conjugates BSA-Aflatoxin B1(B1) had been validated with our anti-Hapten antibody Anti-Aflatoxin B1(B1) mouse monoclonal antibody via competitive ELISA test.
ApplicationELISA tests and other immunoassays;
Lateral flow immunoassay (LFIA);
LTIA
Immunonephelometry
Time-resolved Fluorescence Immunoassay (TRFIA)
FormulationLyophilized from sterile PBS, PH 7.4
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


OVA-Aflatoxin B1(B1)

Cat No.GMP-SMT-144-Ag-2
Bioactivity validationCompetitive immunoassay validation (Competitive ELISA) with hapten-carrier conjugates and anti-Hapten antibody;
Products descriptionCompetitive immunoassay-validated hapten-carrier conjugates OVA-Aflatoxin B1(B1) with anti-Hapten antibody. The hapten hapten-carrier conjugates OVA-Aflatoxin B1(B1) had been validated with our anti-Hapten antibody Anti-Aflatoxin B1(B1) mouse monoclonal antibody via competitive ELISA test.
ApplicationELISA tests and other immunoassays;
Lateral flow immunoassay (LFIA);
LTIA
Immunonephelometry
Time-resolved Fluorescence Immunoassay (TRFIA)
FormulationLyophilized from sterile PBS, PH 7.4
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Anti-Aflatoxin B1(B1) mouse monoclonal antibody

Cat No.GMP-SMT-144-Ab-1
Host of AntibodyMouse IgG
Bioactivity validationCompetitive immunoassay validation (Competitive ELISA) with hapten-carrier conjugates and anti-Hapten antibody;
Lateral flow immunoassay (LFIA);
ELISA IC50 (ppb)0.10
Products descriptionThe anti-Hapten antibody against hapten Aflatoxin B1(B1) had been validated with our hapten hapten-carrier conjugates BSA-Aflatoxin B1(B1) via competitive ELISA test.
ApplicationELISA tests and other immunoassays;
Lateral flow immunoassay (LFIA);
LTIA
Immunonephelometry
Time-resolved Fluorescence Immunoassay (TRFIA)
FormulationLyophilized from sterile PBS, PH 7.4
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Anti-Aflatoxin B1(B1) human monoclonal antibody

Cat No.GMP-SMT-144-Ab-2
Host of AntibodyHuman IgG1
Bioactivity validationCompetitive immunoassay validation (Competitive ELISA) with hapten-carrier conjugates and anti-Hapten antibody;
Lateral flow immunoassay (LFIA);
ELISA IC50 (ppb)0.10
Products descriptionThe anti-Hapten antibody against hapten Aflatoxin B1(B1) had been validated with our hapten hapten-carrier conjugates BSA-Aflatoxin B1(B1) via competitive ELISA test.
ApplicationELISA tests and other immunoassays;
Lateral flow immunoassay (LFIA);
LTIA
Immunonephelometry
Time-resolved Fluorescence Immunoassay (TRFIA)
FormulationLyophilized from sterile PBS, PH 7.4
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Reference




    Data / case study


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    Biomarker Information


    1. Aflatoxin B1 (B1) and its Role in Mycotoxins:

    1.1 Structure and Prevalence (1):

    Aflatoxin B1 (B1) is a mycotoxin of utmost concern due to its significant role in food safety and public health. Chemically, it possesses a unique structure characterized by a bifuranocoumarin moiety and a terminal difuran ring. It is primarily produced by molds belonging to the Aspergillus genus, with Aspergillus flavus and Aspergillus parasiticus being the main culprits behind its generation.

    1.2 Prevalence in Agricultural Commodities (2):

    Aflatoxin B1's notoriety stems from its widespread presence in a variety of agricultural commodities. These include grains such as maize, rice, and wheat, as well as nuts, including peanuts and tree nuts, and legumes like soybeans. The contamination of these essential food sources elevates the significance of Aflatoxin B1 in the realm of mycotoxins.

    1.3 Carcinogenic Potential (3):

    Aflatoxin B1 (B1) is distinguished by its potent carcinogenic properties. Extensive research has demonstrated its capability to form DNA adducts, leading to mutations in critical oncogenes. This ability positions Aflatoxin B1 as a prominent contributor to hepatocellular carcinoma, a form of liver cancer, in both humans and animals.

    1.4 Adverse Health Implications (4):

    Beyond its carcinogenicity, Aflatoxin B1 poses additional health hazards. Exposure to this mycotoxin can lead to immunosuppression, rendering individuals more susceptible to infections. In children, it may result in stunted growth and developmental anomalies. Acute aflatoxicosis, characterized by symptoms like abdominal pain, vomiting, and liver damage, can occur following high-level exposure.

    2. Why Measure Aflatoxin B1 (B1):

    2.1 Regulatory Compliance (5):

    Precise measurement of Aflatoxin B1 (B1) content is not only crucial but also a legal requirement in many countries. Regulatory agencies worldwide have established maximum allowable limits for Aflatoxin B1 in food and feed products. Compliance with these limits is essential to ensure food safety and public health.

    2.2 Protection of Human and Animal Health (6):

    Measuring Aflatoxin B1 is instrumental in safeguarding the well-being of both humans and animals. By detecting and quantifying Aflatoxin B1 in food and feed, we can prevent the consumption of contaminated products, thereby reducing the risk of hepatocellular carcinoma, immunosuppression, and other health-related consequences.

    2.3 Agricultural Applications (7):

    In the agricultural sector, accurate measurement of Aflatoxin B1 plays a vital role in preserving the health and productivity of livestock. Contaminated feed can have severe repercussions, including reduced growth rates and increased susceptibility to diseases. Therefore, regular monitoring of Aflatoxin B1 is essential for livestock farmers to ensure the well-being of their animals.

    2.4 Biopharmaceutical Research (8):

    Beyond its impact on food safety, Aflatoxin B1's detection holds significance in biopharmaceutical research. Companies specializing in anti-small molecules antibodies and small molecules competitive antigens can utilize precise measurements to develop targeted antibodies and antigens for diagnostic and therapeutic applications. This research contributes to the advancement of mycotoxin detection methods and aids in mitigating the health risks associated with Aflatoxin B1 exposure.

    In summary, Aflatoxin B1 (B1) stands as a mycotoxin of paramount concern due to its carcinogenic potential and wide prevalence in various agricultural commodities. Measuring Aflatoxin B1 is essential for regulatory compliance, protecting human and animal health, ensuring agricultural productivity, and advancing biopharmaceutical research. Its comprehensive understanding and accurate detection are fundamental for safeguarding food safety and public health globally.



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