uteinizing hormone(LH) antibody/antigen (BSA/OVA/KLH conjugated hapten)

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anti-uteinizing hormone(LH) antibody and Carrier-coupled antigen/immunogen (hapten-carrier conjugates)

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Product information

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Product Description

BSA-uteinizing hormone(LH)

OVA-uteinizing hormone(LH)

Anti-uteinizing hormone(LH) mouse monoclonal antibody

Anti-uteinizing hormone(LH) human monoclonal antibody

Reference

Validation Data

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Biomarker Information

1. Luteinizing Hormone (LH) and its Role in In Vitro Diagnosis:

1.1 Nature and Function (1):

Luteinizing Hormone (LH) is a glycoprotein hormone with a complex molecular structure produced by the anterior pituitary gland. It stands as a fundamental component of the hypothalamic-pituitary-gonadal (HPG) axis. While LH is not classified as a small molecule, its integral role in reproductive physiology renders it a vital player in in vitro diagnosis.

1.2 Diagnostic Significance (2):

The diagnostic significance of LH cannot be overstated. It serves as a potent indicator in assessing endocrine and reproductive health. By quantifying LH levels in blood or urine samples, medical professionals gain valuable insights into a spectrum of medical conditions.

1.3 Fertility Monitoring (3):

Within the sphere of female reproductive health, LH assumes a central role in predicting and monitoring ovulation. LH surge, characterized by a rapid increase in LH levels, triggers ovulation—a pivotal event in the menstrual cycle that facilitates the release of mature oocytes from ovarian follicles. This process is crucial for conception.

1.4 Testicular Function (4):

In males, LH plays a critical role in stimulating the Leydig cells of the testes to produce testosterone. Measuring LH levels in men can offer insights into testicular function and assist in diagnosing conditions related to testosterone production.

1.5 Role in Polycystic Ovary Syndrome (PCOS) (5):

Polycystic ovary syndrome (PCOS) is a prevalent endocrine disorder in women. LH measurements are particularly useful in the diagnosis of PCOS, as elevated LH levels relative to follicle-stimulating hormone (FSH) are often observed in individuals with this syndrome.

2. The Importance of Measuring Luteinizing Hormone (LH):

2.1 Hormonal Profiling (6):

Accurate measurement of LH levels is instrumental in profiling an individual's hormonal status. Elevated or reduced LH levels serve as indicative markers of underlying endocrine or reproductive irregularities. Physicians and endocrinologists rely on these measurements to diagnose conditions such as hypothalamic dysfunction, primary ovarian failure, and pituitary disorders.

2.2 Fertility Management (7):

LH measurements hold paramount importance for couples aspiring to conceive. Tracking LH surges aids in the precise prediction of ovulation—a window of opportunity for fertilization. Couples can use LH tests to determine the optimal time for intercourse, enhancing their chances of achieving pregnancy.

2.3 Polycystic Ovary Syndrome (PCOS) Identification (8):

LH plays a pivotal role in the hormonal dysregulation observed in PCOS. In individuals with PCOS, LH levels are often elevated compared to FSH levels. This LH/FSH ratio, along with other clinical criteria, contributes to the diagnosis of PCOS.

2.4 Pituitary Function Evaluation (9):

LH assessments are an integral component of evaluating pituitary gland function. Anomalies in LH levels may signify pituitary disorders, such as pituitary adenomas or hypopituitarism. Accurate LH measurements guide clinicians in determining the appropriate course of treatment and monitoring.

2.5 Monitoring Hormone Replacement Therapy (10):

LH measurements are indispensable in the diligent monitoring of hormone replacement therapy. Whether administered for menopause, hypogonadism, or transgender hormone therapy, LH levels must be carefully monitored to ensure that hormonal levels remain within desired therapeutic ranges. Any deviations may necessitate timely adjustments to therapy for optimal health outcomes.

3. Cutting-Edge Diagnostic Tools (11):

Genemedi, a leader in biopharmaceutical solutions, offers a comprehensive suite of advanced diagnostic tools to support LH measurements. Our portfolio includes anti-LH antibodies and a diverse range of competitive antigens, comprising Carrier-coupled antigens, immunogens, hapten-carrier conjugates, BSA-conjugated antigens, and OVA-conjugated antigens. These meticulously developed resources are designed to enable the accurate and sensitive detection of LH in diverse sample matrices.

3.1 Advanced Detection Techniques (12):

The detection of LH in various sample types demands advanced techniques for optimal accuracy and reliability. Genemedi offers a spectrum of sophisticated detection methodologies, each tailored to specific applications:

Enzyme-Linked Immunosorbent Assay (ELISA): ELISA provides exceptional sensitivity and specificity for the quantitative measurement of LH, making it an indispensable tool for research, clinical diagnostics, and reproductive health assessments.

Lateral Flow Immunoassay (LFIA): LFIA enables rapid on-site detection of LH, offering a valuable solution for point-of-care testing, fertility monitoring, and clinical applications.

Colloidal Gold Immunochromatographic Assay: This assay offers user-friendly qualitative detection of LH, delivering rapid results without compromising accuracy, making it

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