Estrone(E1) antibody/antigen (BSA/OVA/KLH conjugated hapten)

anti-Estrone(E1) antibody and Carrier-coupled antigen/immunogen (hapten-carrier conjugates)

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Product information

Catalog No.DescriptionUS $ Price (per mg)
GMP-SMT-185-11. BSA-Estrone(E1)
2. Anti-Estrone(E1) mouse monoclonal antibody
$2709.00
GMP-SMT-185-21. OVA-Estrone(E1)
2. Anti-Estrone(E1) mouse monoclonal antibody
$2709.00
GMP-SMT-185-31. BSA-Estrone(E1)
2. Anti-Estrone(E1) human monoclonal antibody
$2709.00
GMP-SMT-185-41. OVA-Estrone(E1)
2. Anti-Estrone(E1) human monoclonal antibody
$2709.00
GMP-SMT-185-Ag-1BSA-Estrone(E1)$756.00
GMP-SMT-185-Ag-2OVA-Estrone(E1)$756.00
GMP-SMT-185-Ab-1Anti-Estrone(E1) mouse monoclonal antibody$1953.00
GMP-SMT-185-Ab-2Anti-Estrone(E1) human monoclonal antibody$1953.00

Size: 1mg | 10mg | 100mg



Product Description


BSA-Estrone(E1)

Cat No.GMP-SMT-185-Ag-1
Bioactivity validationCompetitive immunoassay validation (Competitive ELISA) with hapten-carrier conjugates and anti-Hapten antibody;
Products descriptionCompetitive immunoassay-validated hapten-carrier conjugates BSA-Estrone(E1) with anti-Hapten antibody. The hapten hapten-carrier conjugates BSA-Estrone(E1) had been validated with our anti-Hapten antibody Anti-Estrone(E1) mouse monoclonal antibody via competitive ELISA test.
ApplicationELISA tests and other immunoassays;
Lateral flow immunoassay (LFIA);
LTIA
Immunonephelometry
Time-resolved Fluorescence Immunoassay (TRFIA)
FormulationLyophilized from sterile PBS, PH 7.4
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


OVA-Estrone(E1)

Cat No.GMP-SMT-185-Ag-2
Bioactivity validationCompetitive immunoassay validation (Competitive ELISA) with hapten-carrier conjugates and anti-Hapten antibody;
Products descriptionCompetitive immunoassay-validated hapten-carrier conjugates OVA-Estrone(E1) with anti-Hapten antibody. The hapten hapten-carrier conjugates OVA-Estrone(E1) had been validated with our anti-Hapten antibody Anti-Estrone(E1) mouse monoclonal antibody via competitive ELISA test.
ApplicationELISA tests and other immunoassays;
Lateral flow immunoassay (LFIA);
LTIA
Immunonephelometry
Time-resolved Fluorescence Immunoassay (TRFIA)
FormulationLyophilized from sterile PBS, PH 7.4
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Anti-Estrone(E1) mouse monoclonal antibody

Cat No.GMP-SMT-185-Ab-1
Host of AntibodyMouse IgG
Bioactivity validationCompetitive immunoassay validation (Competitive ELISA) with hapten-carrier conjugates and anti-Hapten antibody;
Lateral flow immunoassay (LFIA);
ELISA IC50 (ppb)0.4-0.5
Products descriptionThe anti-Hapten antibody against hapten Estrone(E1) had been validated with our hapten hapten-carrier conjugates BSA-Estrone(E1) via competitive ELISA test.
ApplicationELISA tests and other immunoassays;
Lateral flow immunoassay (LFIA);
LTIA
Immunonephelometry
Time-resolved Fluorescence Immunoassay (TRFIA)
FormulationLyophilized from sterile PBS, PH 7.4
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Anti-Estrone(E1) human monoclonal antibody

Cat No.GMP-SMT-185-Ab-2
Host of AntibodyHuman IgG1
Bioactivity validationCompetitive immunoassay validation (Competitive ELISA) with hapten-carrier conjugates and anti-Hapten antibody;
Lateral flow immunoassay (LFIA);
ELISA IC50 (ppb)0.4-0.5
Products descriptionThe anti-Hapten antibody against hapten Estrone(E1) had been validated with our hapten hapten-carrier conjugates BSA-Estrone(E1) via competitive ELISA test.
ApplicationELISA tests and other immunoassays;
Lateral flow immunoassay (LFIA);
LTIA
Immunonephelometry
Time-resolved Fluorescence Immunoassay (TRFIA)
FormulationLyophilized from sterile PBS, PH 7.4
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Reference




    Data / case study


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    Biomarker Information


    1. Estrone (E1) in In Vitro Diagnosis

    Estrone (E1), a pivotal estrogen hormone, holds a paramount position in the realm of in vitro diagnosis. Its significance extends across diverse facets of clinical and scientific inquiry, particularly concerning hormone-related health assessments.

    2. The Clinical and Scientific Relevance of Measuring Estrone (E1)

    The meticulous measurement of Estrone (E1) carries profound implications, deeply rooted in the realms of clinical diagnosis, medical research, and therapeutic intervention. Here, we elucidate the multifaceted reasons that underscore the importance of precise E1 measurement:

    a. Hormone-Related Pathophysiology: Estrone (E1) stands as a cornerstone biomolecule for the assessment and diagnosis of a spectrum of hormone-related pathophysiological conditions. Notably, it finds pronounced relevance in disorders such as polycystic ovary syndrome (PCOS), hormone-dependent cancers (including breast and ovarian cancer), and infertility. Accurate measurement of E1 levels contributes decisively to the early detection, stratification, and efficacious management of these intricate clinical scenarios.

    b. Menopausal Transition Monitoring: E1 levels play a pivotal role in monitoring the dynamic hormonal fluctuations associated with menopausal transitions. The measurement of E1 empowers healthcare professionals to gauge the nuanced hormonal changes that occur during this life stage. This, in turn, guides the formulation of personalized therapeutic modalities and the alleviation of menopause-related symptoms.

    c. Endocrine Homeostasis: The intricate web of endocrine homeostasis relies on the balance and functionality of various hormones, including Estrone (E1). Precise measurement of E1 levels is instrumental in the comprehensive assessment of endocrine system functionality. It aids healthcare practitioners in diagnosing and effectively managing hormonal imbalances, ensuring optimal health outcomes.

    d. Cancer Screening and Risk Stratification: Elevated E1 levels have been closely associated with hormone-dependent malignancies, prominently breast and ovarian cancer. In this context, the measurement of E1 assumes a pivotal role in cancer screening, risk stratification, and early intervention. It provides a critical tool for assessing the risk profile of individuals and guiding clinical decisions for improved prognoses.

    e. Fertility Assessment and Assisted Reproduction: Within the intricate landscape of fertility assessment and assisted reproductive technologies, E1 measurement emerges as a critical parameter. It allows for the comprehensive evaluation of ovarian function and serves as an indicator of the efficacy of fertility interventions. This information is indispensable for couples and healthcare providers navigating the complexities of fertility treatments.

    f. Therapeutic Efficacy Assessment: The measurement of E1 levels is indispensable in the ongoing monitoring of hormone replacement therapies and other hormonal interventions. It ensures that hormonal levels align with therapeutic objectives, optimizing clinical outcomes and patient well-being.

    g. Scientific Inquiry and Clinical Research: Beyond clinical applications, E1 data serves as a foundational element in scientific inquiry and clinical research. Researchers leverage E1 measurements to unravel the intricate nuances of hormone dynamics, contributing to a deeper understanding of their role in health and disease. This knowledge, in turn, informs the development of innovative therapeutic modalities and diagnostic tools.

    In summary, the meticulous measurement of Estrone (E1) stands as a linchpin in the realm of in vitro diagnosis. Genemedi, our distinguished biopharmaceutical enterprise, specializes in providing an expansive array of anti-small molecule antibodies and small molecule competitive antigens. These offerings are precision-engineered to augment the accuracy and efficiency of E1 detection and analysis, empowering healthcare professionals, clinicians, researchers, and scientists to diagnose hormone-related conditions, monitor treatment efficacy, and expand the frontiers of scientific knowledge in the domain of endocrinology. By exploring our solutions, stakeholders unlock unprecedented insights into E1 measurement, thereby catalyzing advancements in healthcare and patient outcomes, while fostering the boundaries of scientific exploration in this critical field.



    About GDU


    GDU

    GDU helps global diagnostic partners in high quality of raw material discovery, development, and application. GDU believes in Protein&antibody Innovation for more reliable diagnostic solutions.