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Description of Small molecules (Chemicals, Antibiotics,Mycotoxins,Hormones,Drugs of Abuse, etc.)

Therapeutic Estrone is the synthetic form of a naturally occurring estrogen estrone. Estrone diffuses through the cell membrane and binds to and subsequently activates the nuclear estrogen receptor found in the reproductive tract, breast, pituitary, hypothalamus, liver, and bone. The activated hormone-receptor complex gets translocated to the nucleus where it binds to the estrogen response element on the DNA and promotes the transcription of target genes involved in the functioning of the female reproductive system and secondary sex characteristics. Estrone increases the hepatic synthesis of sex hormone binding globulin (SHBG), thyroid-binding globulin (TBG), and other serum proteins, as well as suppresses the release of follicle-stimulating hormone (FSH) and luteinizing hormone (LH) from the anterior pituitary.

Estrone is a 17-oxo steroid that is estra-1,3,5(10)-triene substituted by an hydroxy group at position 3 and an oxo group at position 17. It has a role as an estrogen, a bone density conservation agent, an antineoplastic agent, a human metabolite and a mouse metabolite. It is a 3-hydroxy steroid and a 17-oxo steroid. It derives from a hydride of an estrane.

Estrone, one of the major mammalian estrogens, is an aromatized C18 steroid with a 3-hydroxyl group and a 17-ketone. It is produced in vivo from androstenedione or from testosterone via estradiol. It is produced primarily in the ovaries, placenta, and in peripheral tissues (especially adipose tissue) through conversion of adrostenedione. Estrone may be further metabolized to 16-alpha-hydroxyestrone, which may be reduced to estriol by estradiol dehydrogenase.

Order informatioin


Delivery impact due to the Coronavirus Outbreak

With the COVID-19 outbreak in the world, many flights have been cancelled. In order for the customer to receive the goods properly, we use the FedEx Customized Freight (FCF) of Fedex which demands a higher fee. If the delivery fee is more expensive in your area, we will contact you by mail.

Catalog No. Description Price(In USD) Qty (Quantity) Sum(In USD)
GMP-SMT-185-1 1. BSA-Estrone(E1); Size:1mg
2. Anti-Estrone(E1) mouse monoclonal antibody; Size:1mg
1365.5
GMP-SMT-185-1 1. BSA-Estrone(E1); Size:10mg
2. Anti-Estrone(E1) mouse monoclonal antibody; Size:10mg
8232.5
GMP-SMT-185-1 1. BSA-Estrone(E1); Size:100mg
2. Anti-Estrone(E1) mouse monoclonal antibody; Size:100mg
41160.5
GMP-SMT-185-2 1. OVA-Estrone(E1); Size:1mg
2. Anti-Estrone(E1) mouse monoclonal antibody; Size:1mg
1365.5
GMP-SMT-185-2 1. OVA-Estrone(E1); Size:10mg
2. Anti-Estrone(E1) mouse monoclonal antibody; Size:10mg
8232.5
GMP-SMT-185-2 1. OVA-Estrone(E1); Size:100mg
2. Anti-Estrone(E1) mouse monoclonal antibody; Size:100mg
41160.5
GMP-SMT-185-Ab-1 Anti-Estrone(E1) mouse monoclonal antibody; Size:1mg 1043.5
GMP-SMT-185-Ab-1 Anti-Estrone(E1) mouse monoclonal antibody; Size:10mg 6272.5
GMP-SMT-185-Ab-1 Anti-Estrone(E1) mouse monoclonal antibody; Size:100mg 31360.5
GMP-SMT-185-Ag-1 BSA-Estrone(E1); Size:1mg 756.5
GMP-SMT-185-Ag-1 BSA-Estrone(E1); Size:10mg 4536.5
GMP-SMT-185-Ag-1 BSA-Estrone(E1); Size:100mg 22960.5
GMP-SMT-185-Ag-2 OVA-Estrone(E1); Size:1mg 756.5
GMP-SMT-185-Ag-2 OVA-Estrone(E1); Size:10mg 4536.5
GMP-SMT-185-Ag-2 OVA-Estrone(E1); Size:100mg 22960.5
GMP-SMT-185 ≥100mg Inquiry
Shipping Cost: 760.00
Total:



Description


BSA-Estrone(E1)

Cat No. GMP-SMT-185-Ag-1
Bioactivity validation Competitive immunoassay validation (Competitive ELISA) with hapten-carrier conjugates and anti-Hapten antibody;
Products description Competitive immunoassay-validated hapten-carrier conjugates [BSA-Estrone(E1)]with anti-Hapten antibody. The hapten hapten-carrier conjugates [BSA-Estrone(E1)] had been validated with our anti-Hapten antibody[Anti-Estrone(E1) mouse monoclonal antibody] via competitive ELISA test.
Application ELISA tests and other immunoassays;
Lateral flow immunoassay (LFIA);
LTIA
Immunonephelometry
Time-resolved Fluorescence Immunoassay (TRFIA)
Formulation Supplied as a 0.2 μM filtered solution of PBS, PH7.4.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


OVA-Estrone(E1)

Cat No. GMP-SMT-185-Ag-2
Bioactivity validation Competitive immunoassay validation (Competitive ELISA) with hapten-carrier conjugates and anti-Hapten antibody;
Products description Competitive immunoassay-validated hapten-carrier conjugates [ OVA-Estrone(E1)] with anti-Hapten antibody. The hapten hapten-carrier conjugates[ OVA-Estrone(E1)] had been validated with our anti-Hapten antibody[Anti-Estrone(E1) mouse monoclonal antibody] via competitive ELISA test.
Application ELISA tests and other immunoassays;
Lateral flow immunoassay (LFIA);
LTIA
Immunonephelometry
Time-resolved Fluorescence Immunoassay (TRFIA)
Formulation Supplied as a 0.2 μM filtered solution of PBS, PH7.4.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Anti-Estrone(E1) mouse monoclonal antibody

Cat No. GMP-SMT-185-Ab-1
Host of Antibody Mouse IgG
Bioactivity validation Competitive immunoassay validation (Competitive ELISA) with hapten-carrier conjugates and anti-Hapten antibody;
Lateral flow immunoassay (LFIA);
ELISA IC50 (ppb) 0.4-0.5
Products description The anti-Hapten antibody against hapten [Estrone(E1)] had beenvalidated with our hapten hapten-carrier conjugates [BSA-Estrone(E1)] via competitive ELISA test.
Application ELISA tests and other immunoassays;
Lateral flow immunoassay (LFIA);
LTIA
Immunonephelometry
Time-resolved Fluorescence Immunoassay (TRFIA)
Formulation Supplied as a 0.2 μM filtered solution of PBS, PH7.4.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.