Diethylstilbestrol (DES)Hexestrol (HES) antibody/antigen (BSA/OVA/KLH conjugated hapten)

anti-Diethylstilbestrol (DES)Hexestrol (HES) antibody and Carrier-coupled antigen/immunogen (hapten-carrier conjugates)

Target products collectionGo to Hormones diagnostics products collection >>


Product information

Catalog No.DescriptionUS $ Price (per mg)
GMP-SMT-189-11. BSA-Diethylstilbestrol (DES)Hexestrol (HES)
2. Anti-Diethylstilbestrol (DES)Hexestrol (HES) mouse monoclonal antibody
$2709.00
GMP-SMT-189-21. OVA-Diethylstilbestrol (DES)Hexestrol (HES)
2. Anti-Diethylstilbestrol (DES)Hexestrol (HES) mouse monoclonal antibody
$2709.00
GMP-SMT-189-31. BSA-Diethylstilbestrol (DES)Hexestrol (HES)
2. Anti-Diethylstilbestrol (DES)Hexestrol (HES) human monoclonal antibody
$2709.00
GMP-SMT-189-41. OVA-Diethylstilbestrol (DES)Hexestrol (HES)
2. Anti-Diethylstilbestrol (DES)Hexestrol (HES) human monoclonal antibody
$2709.00
GMP-SMT-189-Ag-1BSA-Diethylstilbestrol (DES)Hexestrol (HES)$756.00
GMP-SMT-189-Ag-2OVA-Diethylstilbestrol (DES)Hexestrol (HES)$756.00
GMP-SMT-189-Ab-1Anti-Diethylstilbestrol (DES)Hexestrol (HES) mouse monoclonal antibody$1953.00
GMP-SMT-189-Ab-2Anti-Diethylstilbestrol (DES)Hexestrol (HES) human monoclonal antibody$1953.00

Size: 1mg | 10mg | 100mg



Product Description


BSA-Diethylstilbestrol (DES)Hexestrol (HES)

Cat No.GMP-SMT-189-Ag-1
Bioactivity validationCompetitive immunoassay validation (Competitive ELISA) with hapten-carrier conjugates and anti-Hapten antibody;
Products descriptionCompetitive immunoassay-validated hapten-carrier conjugates BSA-Diethylstilbestrol (DES)Hexestrol (HES) with anti-Hapten antibody. The hapten hapten-carrier conjugates BSA-Diethylstilbestrol (DES)Hexestrol (HES) had been validated with our anti-Hapten antibody Anti-Diethylstilbestrol (DES)Hexestrol (HES) mouse monoclonal antibody via competitive ELISA test.
ApplicationELISA tests and other immunoassays;
Lateral flow immunoassay (LFIA);
LTIA
Immunonephelometry
Time-resolved Fluorescence Immunoassay (TRFIA)
FormulationLyophilized from sterile PBS, PH 7.4
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


OVA-Diethylstilbestrol (DES)Hexestrol (HES)

Cat No.GMP-SMT-189-Ag-2
Bioactivity validationCompetitive immunoassay validation (Competitive ELISA) with hapten-carrier conjugates and anti-Hapten antibody;
Products descriptionCompetitive immunoassay-validated hapten-carrier conjugates OVA-Diethylstilbestrol (DES)Hexestrol (HES) with anti-Hapten antibody. The hapten hapten-carrier conjugates OVA-Diethylstilbestrol (DES)Hexestrol (HES) had been validated with our anti-Hapten antibody Anti-Diethylstilbestrol (DES)Hexestrol (HES) mouse monoclonal antibody via competitive ELISA test.
ApplicationELISA tests and other immunoassays;
Lateral flow immunoassay (LFIA);
LTIA
Immunonephelometry
Time-resolved Fluorescence Immunoassay (TRFIA)
FormulationLyophilized from sterile PBS, PH 7.4
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Anti-Diethylstilbestrol (DES)Hexestrol (HES) mouse monoclonal antibody

Cat No.GMP-SMT-189-Ab-1
Host of AntibodyMouse IgG
Bioactivity validationCompetitive immunoassay validation (Competitive ELISA) with hapten-carrier conjugates and anti-Hapten antibody;
Lateral flow immunoassay (LFIA);
ELISA IC50 (ppb)0.2-0.3
Products descriptionThe anti-Hapten antibody against hapten Diethylstilbestrol (DES)Hexestrol (HES) had been validated with our hapten hapten-carrier conjugates BSA-Diethylstilbestrol (DES)Hexestrol (HES) via competitive ELISA test.
ApplicationELISA tests and other immunoassays;
Lateral flow immunoassay (LFIA);
LTIA
Immunonephelometry
Time-resolved Fluorescence Immunoassay (TRFIA)
FormulationLyophilized from sterile PBS, PH 7.4
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Anti-Diethylstilbestrol (DES)Hexestrol (HES) human monoclonal antibody

Cat No.GMP-SMT-189-Ab-2
Host of AntibodyHuman IgG1
Bioactivity validationCompetitive immunoassay validation (Competitive ELISA) with hapten-carrier conjugates and anti-Hapten antibody;
Lateral flow immunoassay (LFIA);
ELISA IC50 (ppb)0.2-0.3
Products descriptionThe anti-Hapten antibody against hapten Diethylstilbestrol (DES)Hexestrol (HES) had been validated with our hapten hapten-carrier conjugates BSA-Diethylstilbestrol (DES)Hexestrol (HES) via competitive ELISA test.
ApplicationELISA tests and other immunoassays;
Lateral flow immunoassay (LFIA);
LTIA
Immunonephelometry
Time-resolved Fluorescence Immunoassay (TRFIA)
FormulationLyophilized from sterile PBS, PH 7.4
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Biomarker Information


    1. Diethylstilbestrol (DES) and Hexestrol (HES) in In Vitro Diagnosis:

    Diethylstilbestrol (DES) and Hexestrol (HES) occupy a central and distinguished role within the domain of in vitro diagnosis. These two synthetic estrogens, characterized by their structural and functional similarities to natural estrogens, play an indispensable part in the assessment of hormone receptor activity, particularly within the context of estrogen receptor assays. The significance of DES and HES stems from their aptitude to serve as reference compounds in these assays, enabling the meticulous evaluation of estrogen receptor functionality, binding affinity, and response dynamics.

    - Role in In Vitro Diagnosis: DES and HES assume the role of quintessential reference compounds in hormone receptor assays, particularly those focused on estrogen receptors. These assays form a cornerstone of in vitro diagnosis, providing crucial insights into the functionality of these receptors, which are central to a myriad of physiological processes, including those governing reproductive health and the pathogenesis of hormone-related cancers.

    - Structural Resemblance: DES and HES are structurally akin to endogenous estrogens, allowing them to effectively mimic the binding interactions that occur between natural estrogens and their cognate receptors. This structural resemblance endows them with the capacity to act as surrogate ligands for estrogen receptors, enabling the precise assessment of receptor function.

    - Reference Standard: Within the realm of in vitro diagnosis, the accurate quantification and characterization of receptor activity are imperative for the diagnosis and understanding of various health conditions. DES and HES serve as standardized reference compounds against which the binding affinity and responsiveness of estrogen receptors can be gauged, ensuring consistency and reliability in diagnostic assays.

    2. Why Measure Diethylstilbestrol (DES) and Hexestrol (HES) in In Vitro Diagnosis?

    The imperative to measure Diethylstilbestrol (DES) and Hexestrol (HES) in in vitro diagnosis is underscored by a multifaceted tapestry of compelling rationales, reflecting their indispensable role in advancing healthcare and diagnostics:

    a. Hormone Receptor Interrogation: The measurement of DES and HES is integral to hormone receptor assays, which are pivotal for evaluating receptor functionality. By serving as reference compounds, DES and HES facilitate the precise assessment of estrogen receptor binding affinity and activity, allowing healthcare professionals to gain insights into receptor responsiveness.

    b. Detection of Hormonal Disorders: In the diagnostic landscape, DES and HES quantification holds a pivotal position in the detection of hormonal imbalances and disorders. When there is suspicion of hormonal irregularities, these compounds play a crucial role in assessing estrogen receptor responses, thereby aiding in the diagnosis and understanding of conditions related to reproductive health and hormone-related cancers.

    c. Efficacy Appraisal of Hormone-Based Therapies: Patients undergoing hormone-based therapies, such as those for hormone-sensitive cancers or reproductive health management, benefit from the monitoring of estrogen receptor activity through DES and HES assays. This monitoring enables healthcare providers to evaluate the efficacy of treatment and make informed decisions regarding therapy adjustments, ensuring that patients receive optimal care.

    d. Research Advancements: Within the realm of in vitro diagnostics, DES and HES measurements serve as fundamental building blocks for research and assay development. Researchers rely on these reference compounds to design and validate innovative diagnostic assays, fostering advancements in the field. These assays contribute to enhanced diagnostic precision, expanded diagnostic capabilities, and improved patient care.

    e. Quality Assurance: Manufacturers of in vitro diagnostic products place paramount importance on the precise quantification of DES and HES. These measurements are essential for maintaining the quality, consistency, and reliability of diagnostic tests and reagents. Rigorous quality assurance safeguards that diagnostic tests perform consistently and deliver dependable results to healthcare practitioners and patients alike.

    In summation, the measurement of Diethylstilbestrol (DES) and Hexestrol (HES) within the sphere of in vitro diagnosis stands as a linchpin in the assessment of estrogen receptor functionality, the detection of hormonal disorders, the evaluation of hormone-based therapies, the advancement of diagnostic research, and the ensurance of diagnostic product quality. These small molecules epitomize the quintessential facets of diagnostic medicine, enriching our understanding of hormone-related health conditions and fortifying diagnostic precision. Their presence within the diagnostic arsenal underscores their indispensable role in advancing healthcare and diagnostics.



    About GDU


    GDU

    GDU helps global diagnostic partners in high quality of raw material discovery, development, and application. GDU believes in Protein&antibody Innovation for more reliable diagnostic solutions.