IFNGR1,IFNGR: Target/Biomarker Introduction, products summarized (antibody/ADC/bispecific/antigen/ORF vector/VLP) and disease/indication/condition/MOA for drug discovery and IVD
It's the GeneMedi's summary page for Target/Biomarker Introduction of IFNGR,IFNGR1. The page also collects GeneMedi's different modalities and formats products for IFNGR in therapeutics/drug discovery and IVD diagnostics, which is including antibody, ADC, bispecific, antigen, ORF vector, VLP, etc. With GeneMedi's target-insight database-GM ITD database, the IFNGR target is also connected to human indications/diseases/conditions/MOA.
Target sublocation: Transmembrane Protein.
This gene (IFNGR1) encodes the ligand-binding chain (alpha) of the gamma interferon receptor. Human interferon-gamma receptor is a heterodimer of IFNGR1 and IFNGR2. A genetic variation in IFNGR1 is associated with susceptibility to Helicobacter pylori infection. In addition, defects in IFNGR1 are a cause of mendelian susceptibility to mycobacterial disease, also known as familial disseminated atypical mycobacterial infection. [provided by RefSeq, Jul 2008]
Target ID | GM-IO066 |
Target Name | IFNGR |
Gene ID | 3459 |
Gene Official Name | IFNGR1 |
Gene Alias | CD119, IFNGR, IMD27A, IMD27B |
Protein Sub-location | Transmembrane Protein |
Category | Therapeutics Target, INN Index, Immuno-oncology Target |
Pre-made IFNGR-specific INN-index biosimilar (antibody&conjugates)-interferon gamma
Anti-IFNGR therapeutic INN-index antibodies and conjugates are biosimilars expressed by mammalian cell line as a benchmark reference therapeutic antibody for drug discovery, target MOA research, cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Cat No. | Products Name (INN Index) | INN Name | Previous Name | Target | Format | Order |
GMP-Bios-INN-874 | Pre-Made Interferon Gamma Biosimilar, Recombinant Protein targeting IFNGR1: Recombinant therapeutic protein targeting CD119/IFNGR/IMD27A/IMD27B | interferon gamma | IFNGR1 | Recombinant Protein | ![]() |
Pre-made anti-IFNGR inhibitory monoclonal antibody(mab, blocking antibody inhibitor)-benchmark reference antibody for drug discovery and mechanism of action (MOA) research
Pre-made anti-IFNGR benchmark inhibitory monoclonal antibody(mab, blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). The anti-IFNGR mab is expressed and produced by mammalian cell line as a benchmark reference therapeutic antibody for biological drug discovery items including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Cat No. | Antibody Name | Format | Classified by tag | Order |
GM-Tg-hg-IO066-Ab | Anti-IFNGR/IFNGR1 monoclonal antibody | mab | Biofunctional antibody, Therapeutics Target antibody | ![]() |