SFRP5: Target/Biomarker Introduction, products summarized (antibody/ADC/bispecific/antigen/ORF vector/VLP) and disease/indication/condition/MOA for drug discovery and IVD
It's the GeneMedi's summary page for Target/Biomarker Introduction of SFRP5. The page also collects GeneMedi's different modalities and formats products for SFRP5 in therapeutics/drug discovery and IVD diagnostics, which is including antibody, ADC, bispecific, antigen, ORF vector, VLP, etc. With GeneMedi's target-insight database-GM ITD database, the SFRP5 target is also connected to human indications/diseases/conditions/MOA.
Target sublocation: Secreted Protein/Potential Cytokines.
Secreted frizzled-related protein 5 (SFRP5) is a member of the SFRP family that contains a cysteine-rich domain homologous to the putative Wnt-binding site of Frizzled proteins. SFRPs act as soluble modulators of Wnt signaling. SFRP5 and SFRP1 may be involved in determining the polarity of photoreceptor cells in the retina. SFRP5 is highly expressed in the retinal pigment epithelium, and moderately expressed in the pancreas. [provided by RefSeq, Jul 2008]
Target ID | GM-SE1285 |
Target Name | SFRP5 |
Gene ID | 6425,54612,309377,707738,486826,101088696,282069,100070673 |
Gene Symbol and Synonyms | SARP3,SFRP5 |
Uniprot Accession | Q5T4F7,Q9XSC1 |
Uniprot Entry Name | SFRP5_HUMAN,SFRP5_BOVIN |
Protein Sub-location | Secreted Protein/Potential Cytokines |
Category | |
Disease | Cancer |
Gene Ensembl | ENSG00000120057 |
Target Classification | Tumor-associated antigen (TAA) |
Pre-made anti-SFRP5 inhibitory monoclonal antibody(mab, blocking antibody inhibitor)-benchmark antibody for drug discovery and mechanism of action (MOA) research
Pre-made anti-SFRP5 benchmark inhibitory monoclonal antibody(mab, blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). The anti-SFRP5 mab is expressed and produced by mammalian cell line as a benchmark reference therapeutic antibody for biological drug discovery items including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Antibody Name | Species | Format | Classified by tag | Detail |
Anti-SFRP5 monoclonal antibody | Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine | mab | FACS/Biofunctional Antibody | Detail |
Recombinant multi-species SFRP5/ SARP3 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis
Genemedi produces Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine SFRP5 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
Products Name | Species | Expression Platform | Detail |
SFRP5 protein | Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine | Mammalian cell | Detail |
Pre-made SFRP5 viral vector in GM Promise-ORFTM
Cat No. | Products name | NM ID | Species | Type | Detail |
vGMLP004521 | human SFRP5 Lentivirus particle | NM_003015 | Human | Lentivirus particle | Detail |
pGMLP004521 | human SFRP5 Lentivirus plasmid | NM_003015 | Human | Lentivirus plasmid | Detail |
pGMAAV000278 | house mouse Sfrp5 AAV plasmid | NM_018780.3 | House Mouse | AAV plasmid | Detail |
pGMLPm002147 | mouse Sfrp5 Lentivirus plasmid | NM_018780 | Mouse | Lentivirus plasmid | Detail |
vGMAAV000278 | house mouse Sfrp5 AAV particle | NM_018780.3 | House Mouse | AAV particle | Detail |
vGMLPm002147 | mouse Sfrp5 Lentivirus particle | NM_018780 | Mouse | Lentivirus particle | Detail |
About Promise-ORFTM:
Discover the largest collection of ORF/cDNA expression clones from different species, including human, mouse, rat, and more with GeneMedi's Promise-ORFTM. Our collection of ORFs expression clones come in verified mammalian or viral vectors lentivirus, AAV, and adenovirus) and our Promise-ORFTM viral-ready expression vectors make it easy for you to improve viral vector packaging efficiency or directly transfect mammalian cells, resulting in stronger and easier expression detection. Click to search your GOI
If you want to obtain higher quantities of plasmids (mg), please visit GM TransExcellent Plasmid DNA Rapid Preparation Service.