CB2/CNR2: Target/Biomarker Introduction, products summarized (antibody/ADC/bispecific/antigen/ORF vector/VLP) and disease/indication/condition/MOA for drug discovery and IVD

It's the GeneMedi's summary page for Target/Biomarker Introduction of CB2/CNR2. The page also collects GeneMedi's different modalities and formats products for CB2 in therapeutics/drug discovery and IVD diagnostics, which is including antibody, ADC, bispecific, antigen, ORF vector, VLP, etc. With GeneMedi's target-insight database-GM ITD database, the CB2 target is also connected to human indications/diseases/conditions/MOA.

Target sublocation: Transmembrane Protein.

The cannabinoid delta-9-tetrahydrocannabinol is the principal psychoactive ingredient of marijuana. The proteins encoded by this gene and the cannabinoid receptor 1 (brain) (CNR1) gene have the characteristics of a guanine nucleotide-binding protein (G-protein)-coupled receptor for cannabinoids. They inhibit adenylate cyclase activity in a dose-dependent, stereoselective, and pertussis toxin-sensitive manner. These proteins have been found to be involved in the cannabinoid-induced CNS effects (including alterations in mood and cognition) experienced by users of marijuana. The cannabinoid receptors are members of family 1 of the G-protein-coupled receptors. [provided by RefSeq, Jul 2008]

Target IDGM-T37693
Target NameCB2
Gene ID1269,12802,57302,711155,612289,101100234,539769,100071536
Gene Symbol and SynonymsCB-2,CB2,CB2-R,CB2C,CNR2,CNR2C,CX5
Uniprot AccessionP34972,Q9QZN9
Uniprot Entry NameCNR2_HUMAN,CNR2_RAT
Protein Sub-locationTransmembrane Protein
CategoryTherapeutics Target, Immuno-oncology Target
DiseaseN/A
Gene EnsemblENSG00000188822
Target ClassificationCheckpoint-Immuno Oncology, GPCR


Pre-made anti-CB2 inhibitory monoclonal antibody(mab, blocking antibody inhibitor)-benchmark antibody for drug discovery and mechanism of action (MOA) research

Pre-made anti-CB2 benchmark inhibitory monoclonal antibody(mab, blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). The anti-CB2 mab is expressed and produced by mammalian cell line as a benchmark reference therapeutic antibody for biological drug discovery items including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.

Antibody NameSpeciesFormatClassified by tagDetail
Anti-CB2/CNR2 monoclonal antibodyHuman, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, EquinemabFACS/Biofunctional Antibody, Therapeutics Target antibodyDetail



Multi-species CNR2/ CB2/ CB-2 VLP (virus-like particle) for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine CB2/CNR2 VLP (virus-like particle) for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.

Products NameSpeciesExpression PlatformDetail
CB2/CNR2 VLP (virus-like particle)Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, EquineMammalian cellProducts Developing



Pre-made CNR2 viral vector in GM Promise-ORFTM

Cat No.Products nameNM IDSpeciesTypeDetail
vGMLP003590human CNR2 Lentivirus particleNM_001841HumanLentivirus particleDetail
pGMLP003590human CNR2 Lentivirus plasmidNM_001841HumanLentivirus plasmidDetail
pGMAAV000242house mouse Cnr2 AAV plasmidNM_001305278.1House MouseAAV plasmidDetail
pGMLPm001962mouse Cnr2 Lentivirus plasmidNM_001305278.1MouseLentivirus plasmidDetail
pGMLPm005447mouse Cnr2 Lentivirus plasmidNM_009924MouseLentivirus plasmidDetail
vGMAAV000242house mouse Cnr2 AAV particleNM_001305278.1House MouseAAV particleDetail
vGMLPm001962mouse Cnr2 Lentivirus particleNM_001305278.1MouseLentivirus particleDetail
vGMLPm005447mouse Cnr2 Lentivirus particleNM_009924MouseLentivirus particleDetail

About Promise-ORFTM:
Discover the largest collection of ORF/cDNA expression clones from different species, including human, mouse, rat, and more with GeneMedi's Promise-ORFTM. Our collection of ORFs expression clones come in verified mammalian or viral vectors lentivirus, AAV, and adenovirus) and our Promise-ORFTM viral-ready expression vectors make it easy for you to improve viral vector packaging efficiency or directly transfect mammalian cells, resulting in stronger and easier expression detection. Click to search your GOI

If you want to obtain higher quantities of plasmids (mg), please visit GM TransExcellent Plasmid DNA Rapid Preparation Service.






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