CB2/CNR2: Target/Biomarker Introduction, products summarized (antibody/ADC/bispecific/antigen/ORF vector/VLP) and disease/indication/condition/MOA for drug discovery and IVD
It's the GeneMedi's summary page for Target/Biomarker Introduction of CB2/CNR2. The page also collects GeneMedi's different modalities and formats products for CB2 in therapeutics/drug discovery and IVD diagnostics, which is including antibody, ADC, bispecific, antigen, ORF vector, VLP, etc. With GeneMedi's target-insight database-GM ITD database, the CB2 target is also connected to human indications/diseases/conditions/MOA.
Target sublocation: Transmembrane Protein.
The cannabinoid delta-9-tetrahydrocannabinol is the principal psychoactive ingredient of marijuana. The proteins encoded by this gene and the cannabinoid receptor 1 (brain) (CNR1) gene have the characteristics of a guanine nucleotide-binding protein (G-protein)-coupled receptor for cannabinoids. They inhibit adenylate cyclase activity in a dose-dependent, stereoselective, and pertussis toxin-sensitive manner. These proteins have been found to be involved in the cannabinoid-induced CNS effects (including alterations in mood and cognition) experienced by users of marijuana. The cannabinoid receptors are members of family 1 of the G-protein-coupled receptors. [provided by RefSeq, Jul 2008]
|Gene Symbol and Synonyms||CB-2,CB2,CB2-R,CB2C,CNR2,CNR2C,CX5|
|Uniprot Entry Name||CNR2_HUMAN,CNR2_RAT|
|Protein Sub-location||Transmembrane Protein|
|Category||Therapeutics Target, Immuno-oncology Target|
|Target Classification||Checkpoint-Immuno Oncology, GPCR|
Pre-made anti-CB2 inhibitory monoclonal antibody(mab, blocking antibody inhibitor)-benchmark antibody for drug discovery and mechanism of action (MOA) research
Pre-made anti-CB2 benchmark inhibitory monoclonal antibody(mab, blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). The anti-CB2 mab is expressed and produced by mammalian cell line as a benchmark reference therapeutic antibody for biological drug discovery items including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
|Antibody Name||Species||Format||Classified by tag||Detail|
|Anti-CB2/CNR2 monoclonal antibody||Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine||mab||FACS/Biofunctional Antibody, Therapeutics Target antibody||Detail|
Multi-species CNR2/ CB2/ CB-2 VLP (virus-like particle) for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis
Genemedi produces Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine CB2/CNR2 VLP (virus-like particle) for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
|Products Name||Species||Expression Platform||Detail|
|CB2/CNR2 VLP (virus-like particle)||Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine||Mammalian cell||Products Developing|
Pre-made CNR2 viral vector in GM Promise-ORFTM
|Cat No.||Products name||NM ID||Species||Type||Detail|
|vGMLP003590||human CNR2 Lentivirus particle||NM_001841||Human||Lentivirus particle||Detail|
|pGMLP003590||human CNR2 Lentivirus plasmid||NM_001841||Human||Lentivirus plasmid||Detail|
|pGMAAV000242||house mouse Cnr2 AAV plasmid||NM_001305278.1||House Mouse||AAV plasmid||Detail|
|pGMLPm001962||mouse Cnr2 Lentivirus plasmid||NM_001305278.1||Mouse||Lentivirus plasmid||Detail|
|pGMLPm005447||mouse Cnr2 Lentivirus plasmid||NM_009924||Mouse||Lentivirus plasmid||Detail|
|vGMAAV000242||house mouse Cnr2 AAV particle||NM_001305278.1||House Mouse||AAV particle||Detail|
|vGMLPm001962||mouse Cnr2 Lentivirus particle||NM_001305278.1||Mouse||Lentivirus particle||Detail|
|vGMLPm005447||mouse Cnr2 Lentivirus particle||NM_009924||Mouse||Lentivirus particle||Detail|
Discover the largest collection of ORF/cDNA expression clones from different species, including human, mouse, rat, and more with GeneMedi's Promise-ORFTM. Our collection of ORFs expression clones come in verified mammalian or viral vectors lentivirus, AAV, and adenovirus) and our Promise-ORFTM viral-ready expression vectors make it easy for you to improve viral vector packaging efficiency or directly transfect mammalian cells, resulting in stronger and easier expression detection. Click to search your GOI
If you want to obtain higher quantities of plasmids (mg), please visit GM TransExcellent Plasmid DNA Rapid Preparation Service.