Entrez Gene ID |
Official Symbol |
Species |
Alias Names |
Background |
340273 |
IO target |
|
ABCB5alphabeta, EST422562, ABCB5 |
ATP binding cassette subfamily B member 5 |
6868 |
IO target |
|
ADAM18, CD156B, CSVP, NISBD, NISBD1, TACE |
ADAM metallopeptidase domain 17 |
8754 |
IO target |
|
CORD9, MCMP, MDC9, Mltng |
ADAM metallopeptidase domain 9 |
2015 |
IO target |
|
EMR1, TM7LN3 |
adhesion G protein-coupled receptor E1 |
284 |
IO target |
|
AGP1, AGPT, ANG1 |
angiopoietin 1 |
290 |
IO target |
|
APN, CD13, GP150, LAP1, P150, PEPN |
alanyl aminopeptidase, membrane |
367 |
IO target |
|
AIS8, DHTR, HUMARA, HYSP1, KD, NR3C4, SBMA, SMAX1, TFM, AR |
androgen receptor |
472 |
IO target |
|
AT1, ATA, ATC, ATD, ATDC, ATE, TEL1, TELO1 |
ATM serine/threonine kinase |
545 |
IO target |
|
FCTCS, FRP1, MEC1, SCKL, SCKL1 |
ATR serine/threonine kinase |
2583 |
IO target |
|
GALGT, GALNACT, GalNAc-T, SPG26 |
beta-1,4-N-acetyl-galactosaminyltransferase 1 |
575 |
IO target |
|
GDAIF; brain-specific angiogenesis inhibitor 1 |
Angiogenesis is controlled by a local balance between stimulators and inhibitors of new vessel growth and is suppressed under normal physiologic conditions. Angiogenesis has been shown to be essential for growth and metastasis of solid tumors. In order to obtain blood supply for their growth, tumor cells are potently angiogenic and attract new vessels as results of increased secretion of inducers and decreased production of endogenous negative regulators. BAI1 contains at least one 'functional' p53-binding site within an intron, and its expression has been shown to be induced by wildtype p53. There are two other brain-specific angiogenesis inhibitor genes, designated BAI2 and BAI3 which along with BAI1 have similar tissue specificities and structures, however only BAI1 is transcriptionally regulated by p53. BAI1 is postulated to be a member of the secretin receptor family, an inhibitor of angiogenesis and a growth suppressor of glioblastomas [provided by RefSeq, Jul 2008] |
332 |
IO target |
|
API4, EPR-1 |
baculoviral IAP repeat containing 5 |
682 |
IO target |
|
5F7, CD147, EMMPRIN, EMPRIN, OK, SLC7A11, TCSF |
basigin (Ok blood group) |
728 |
IO target |
|
C5A, C5AR, C5R1, CD88 |
complement C5a receptor 1 |
868 |
IO target |
|
Cbl-b, Nbla00127, RNF56 |
Cbl proto-oncogene B |
933 |
IO target |
|
SIGLEC-2, SIGLEC2 |
CD22 molecule |
29126 |
IO target |
|
B7-H, B7H1, PD-L1, PDCD1L1, PDCD1LG1, PDL1 |
CD274 molecule |
80381 |
IO target |
|
4Ig-B7-H3, B7-H3, B7H3, B7RP-2 |
CD276 molecule |
916 |
IO target |
|
IMD18, T3E, TCRE |
CD3e molecule |
959 |
IO target |
|
CD154, CD40L, HIGM1, IGM, IMD3, T-BAM, TNFSF5, TRAP, gp39, hCD40L |
CD40 ligand |
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