Entrez Gene ID Official Symbol Species Alias Names Background
91 Kinase ACTRIB; ACVRLK4; ALK4; SKR2; activin A receptor, type IB; activin A receptor, type II-like kinase 4; activin receptor type-1B; activin receptor-like kinase 4; serine/threonine-protein kinase receptor R2 This gene encodes an activin A type IB receptor. Activins are dimeric growth and differentiation factors which belong to the transforming growth factor-beta (TGF-beta) superfamily of structurally related signaling proteins. Activins signal through a heteromeric complex of receptor serine kinases which include at least two type I and two type II receptors. This protein is a type I receptor which is essential for signaling. Mutations in this gene are associated with pituitary tumors. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Jun 2010]