Entrez Gene ID Official Symbol Species Alias Names Background
9578 Kinase CDC42 binding protein kinase beta (DMPK-like); CDC42-binding protein kinase beta (DMPK-like); CDC42BP-beta; DMPK-like beta; MRCK beta; MRCKB; myotonic dystrophy kinase-related CDC42-binding kinase beta; myotonic dystrophy protein kinase-like beta; serine/threonine-protein kinase MRCK beta This gene encodes a member of the serine/threonine protein kinase family. The encoded protein contains a Cdc42/Rac-binding p21 binding domain resembling that of PAK kinase. The kinase domain of this protein is most closely related to that of myotonic dystrophy kinase-related ROK. Studies of the similar gene in rat suggested that this kinase may act as a downstream effector of Cdc42 in cytoskeletal reorganization. [provided by RefSeq, Jul 2008]