PRMT5: Target/Biomarker Introduction, products summarized (antibody/ADC/bispecific/antigen/ORF vector/VLP) and disease/indication/condition/MOA for drug discovery and IVD

It's the GeneMedi's summary page for Target/Biomarker Introduction of PRMT5. The page also collects GeneMedi's different modalities and formats products for PRMT5 in therapeutics/drug discovery and IVD diagnostics, which is including antibody, ADC, bispecific, antigen, ORF vector, VLP, etc. With GeneMedi's target-insight database-GM ITD database, the PRMT5 target is also connected to human indications/diseases/conditions/MOA.

Target sublocation: Introcelluar Protein.

This gene encodes an enzyme that belongs to the methyltransferase family. The encoded protein catalyzes the transfer of methyl groups to the amino acid arginine, in target proteins that include histones, transcriptional elongation factors and the tumor suppressor p53. This gene plays a role in several cellular processes, including transcriptional regulation, and the assembly of small nuclear ribonucleoproteins. A pseudogene of this gene has been defined on chromosome 4. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Sep 2015]

Target IDGM-T82665
Target NamePRMT5
Gene ID10419,27374,364382,712718,480242,101091118,515594,100052729
Gene Symbol and SynonymsHRMT1L5,HSL7,IBP72,JBP1,PRMT5,SKB1,SKB1Hs
Uniprot AccessionO14744,A7YW45
Uniprot Entry NameANM5_HUMAN,ANM5_BOVIN
Protein Sub-locationIntrocelluar Protein
CategoryTherapeutics Target
DiseaseProstate Cancer
Gene EnsemblENSG00000100462
Target ClassificationN/A


Pre-made anti-PRMT5 inhibitory monoclonal antibody(mab, blocking antibody inhibitor)-benchmark antibody for drug discovery and mechanism of action (MOA) research

Pre-made anti-PRMT5 monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). The anti-PRMT5 mab is expressed and produced by mammalian cell line as a benchmark reference therapeutic antibody for biological drug discovery items including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.

Antibody NameSpeciesFormatClassified by tagDetail
Anti-PRMT5 monoclonal antibodyHuman, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, EquinemabTherapeutics Target antibodyDetail



Recombinant multi-species ANM5/ PRMT5/ HRMT1L5 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine PRMT5 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.

Products NameSpeciesExpression PlatformDetail
PRMT5 proteinHuman, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, EquineMammalian cellDetail



Pre-made PRMT5 viral vector in GM Promise-ORFTM

Cat No.Products nameNM IDSpeciesTypeDetail
vGMLV000196human PRMT5 Lentivirus particleNM_006109HumanLentivirus particleDetail
vGMAD000192human PRMT5 Adenovirus particleNM_006109.4HumanAdenovirus particleDetail
vGMLV000778human PRMT5 Lentivirus particleNM_006109.5HumanLentivirus particleDetail
pGMLV000778human PRMT5 Lentivirus plasmidNM_006109.5HumanLentivirus plasmidDetail
pGMAD000192human PRMT5 Adenovirus plasmidNM_006109.4HumanAdenovirus plasmidDetail
pGMLV000196human PRMT5 Lentivirus plasmidNM_006109HumanLentivirus plasmidDetail
pGMLPm003039mouse Prmt5 Lentivirus plasmidNM_013768MouseLentivirus plasmidDetail
vGMLPm003039mouse Prmt5 Lentivirus particleNM_013768MouseLentivirus particleDetail

About Promise-ORFTM:
Discover the largest collection of ORF/cDNA expression clones from different species, including human, mouse, rat, and more with GeneMedi's Promise-ORFTM. Our collection of ORFs expression clones come in verified mammalian or viral vectors lentivirus, AAV, and adenovirus) and our Promise-ORFTM viral-ready expression vectors make it easy for you to improve viral vector packaging efficiency or directly transfect mammalian cells, resulting in stronger and easier expression detection. Click to search your GOI

If you want to obtain higher quantities of plasmids (mg), please visit GM TransExcellent Plasmid DNA Rapid Preparation Service.






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