Diagnostic antibodies and antigens for Inflammation/autoimmune/inflammatory diseases testing-IL-6, PCT, CRP, SAA, IFNγ, AQP4, HBP, MOG, S100-A9, TPO, SAA1, TNFα，α-defensin 1, α-defensin 5

Inflammation/autoimmune/inflammatory diseases occur when the immune system attacks the normal tissue within joints, vasculature, and other organ systems, causing inflammation, pain, diminished mobility, fatigue, and other non-specific symptoms. The strong overlap of signs and symptoms among the autoimmune diseases can lead to delays in diagnosis and appropriate treatment. However, immunodiagnostics has been developed to detect the inflammation/autoimmune/inflammatory disease such as ankylosing spondylitis, bacterial infections, bacterial meningitis, cerebrovascular diseases, crohn's disease, fungal infection, graves' disease, inflammatory amyloidosis, inflammatory bowel disease, mog antibody disease, osteomyelitis, rheumatoid arthritis, sepsis, respiratory illnesses and so on at an early stage. Biomarkers have been developed to detect this autoimmune disease at an early stage. Detecting the quantity of marker proteins from different samples may benefit from ELISA, Lateral flow immunoassay (LFIA), colloidal gold immunochromatographic assay, Chemiluminescent immunoassay (CLIA), turbidimetric inhibition immuno assay (TINIA), immunonephelometry and POCT.

Classification: IL-6 PCT CRP SAA IFNγ AQP4 HBP MOG S100-A9 TPO SAA1 TNFα MPA CCP alpha defensin 1 alpha defensin 5

Interleukin 6 (IL-6)

Cat No.	Species	Biomarker	Disease	Cat No.of Antigen	Bioactivity validation of Antigen	Cat No.of Antibodies	Bioactivity validation of Antibodies	Order
GMP-h-IL-6	Human	Interleukin 6 (IL-6)	systemic juvenile idiopathic arthritis, systemic lupus erythematosus, ankylosing spondylitis, psoriasis and Crohn's disease.	GMP-h-IL-6-Ag01: Recombinant human IL-6 Protein	Interleukin 6 (IL-6) antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests,and other immunoassays as control material in IL-6 level test of Inflammation/autoimmune/inflammatory disease(systemic juvenile idiopathic arthritis, systemic lupus erythematosus, ankylosing spondylitis, psoriasis and Crohn's disease.) and related syndrome evaluation.	GMP-h-IL-6-Ab01; GMP-h-IL-6-Ab02: Anti-human IL-6 mouse monoclonal antibody(mAb)	Human Interleukin 6 (IL-6) antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other Interleukin 6 (IL-6) antibodies in IL-6 level test of Inflammation/autoimmune/inflammatory disease (systemic juvenile idiopathic arthritis, systemic lupus erythematosus, ankylosing spondylitis, psoriasis and Crohn's disease.) and related syndrome evaluation.

procalcitonin (PCT)

Cat No.	Species	Biomarker	Disease	Cat No.of Antigen	Bioactivity validation of Antigen	Cat No.of Antibodies	Bioactivity validation of Antibodies	Order
GMP-h-PCT	Human	procalcitonin (PCT)	Sepsis; Respiratory illnesses; bacterial meningitis and etc.	GMP-h-PCT-Ag01: Recombinant human PCT Protein	procalcitonin (PCT) antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests,and other immunoassays as control material in PCT level test of Inflammation/autoimmune/inflammatory disease(Sepsis; Respiratory illnesses; bacterial meningitis and etc.) and related syndrome evaluation.	GMP-h-PCT-Ab01; GMP-h-PCT-Ab02: Anti-human PCT mouse monoclonal antibody(mAb)	Human procalcitonin (PCT) antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other procalcitonin (PCT) antibodies in PCT level test of Inflammation/autoimmune/inflammatory disease (Sepsis; Respiratory illnesses; bacterial meningitis and etc.) and related syndrome evaluation.

C-Reactive Protein (CRP)

Cat No.	Species	Biomarker	Disease	Cat No.of Antigen	Bioactivity validation of Antigen	Cat No.of Antibodies	Bioactivity validation of Antibodies	Order
GMP-h-CRP	Human	C-Reactive Protein (CRP)	Bacterial infections, sepsis, fungal infection, Inflammatory bowel disease, autoimmune, cancer and etc disorder, osteomyelitis	GMP-h-CRP-Ag01: Recombinant human CRP Protein	C-Reactive Protein (CRP) antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests,and other immunoassays as control material in CRP level test of Inflammation/autoimmune/inflammatory disease(Bacterial infections, sepsis, fungal infection, Inflammatory bowel disease, autoimmune, cancer and etc disorder, osteomyelitis) and related syndrome evaluation.	GMP-h-CRP-Ab01; GMP-h-CRP-Ab02: Anti-human CRP mouse monoclonal antibody(mAb)	Human C-Reactive Protein (CRP) antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other C-Reactive Protein (CRP) antibodies in CRP level test of Inflammation/autoimmune/inflammatory disease (Bacterial infections, sepsis, fungal infection, Inflammatory bowel disease, autoimmune, cancer and etc disorder, osteomyelitis) and related syndrome evaluation.

Serum Amyloid A (SAA)

Cat No.	Species	Biomarker	Disease	Cat No.of Antigen	Bioactivity validation of Antigen	Cat No.of Antibodies	Bioactivity validation of Antibodies	Order
GMP-h-SAA	Human	Serum Amyloid A (SAA)	Rheumatoid arthritis, inflammatory bowel disease (Crohn’s disease, ulcerative colitis), and chronic infections	GMP-h-SAA-Ag01: Recombinant human SAA Protein	Serum Amyloid A (SAA) antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests,and other immunoassays as control material in SAA level test of Inflammation/autoimmune/inflammatory disease(Rheumatoid arthritis, inflammatory bowel disease (Crohn’s disease, ulcerative colitis), and chronic infections) and related syndrome evaluation.	GMP-h-SAA-Ab01; GMP-h-SAA-Ab02: Anti-human SAA mouse monoclonal antibody(mAb)	Human Serum Amyloid A (SAA) antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other Serum Amyloid A (SAA) antibodies in SAA level test of Inflammation/autoimmune/inflammatory disease (Rheumatoid arthritis, inflammatory bowel disease (Crohn’s disease, ulcerative colitis), and chronic infections) and related syndrome evaluation.

Interferon gamma (IFNγ)

Cat No.	Species	Biomarker	Disease	Cat No.of Antigen	Bioactivity validation of Antigen	Cat No.of Antibodies	Bioactivity validation of Antibodies	Order
GMP-h-IFNγ	Human	Interferon gamma (IFNγ)	inflamation, autoimmune disease	GMP-h-IFNγ-Ag01: Recombinant human IFNγ Protein	Interferon gamma (IFNγ) antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests,and other immunoassays as control material in IFNγ level test of Inflammation/autoimmune/inflammatory disease(inflamation, autoimmune disease) and related syndrome evaluation.	GMP-h-IFNγ-Ab01; GMP-h-IFNγ-Ab02: Anti-human IFNγ mouse monoclonal antibody(mAb)	Human Interferon gamma (IFNγ) antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other Interferon gamma (IFNγ) antibodies in IFNγ level test of Inflammation/autoimmune/inflammatory disease (inflamation, autoimmune disease) and related syndrome evaluation.

aquaporin-4 (AQP4)

Cat No.	Species	Biomarker	Disease	Cat No.of Antigen	Bioactivity validation of Antigen	Cat No.of Antibodies	Bioactivity validation of Antibodies	Order
GMP-h-AQP4	Human	aquaporin-4 (AQP4)	Cerebrovascular diseases	GMP-h-AQP4-Ag01: Recombinant human AQP4 Protein	aquaporin-4 (AQP4) antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests,and other immunoassays as control material in AQP4 level test of Inflammation/autoimmune/inflammatory disease(Cerebrovascular diseases) and related syndrome evaluation.	GMP-h-AQP4-Ab01; GMP-h-AQP4-Ab02: Anti-human AQP4 mouse monoclonal antibody(mAb)	Human aquaporin-4 (AQP4) antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other aquaporin-4 (AQP4) antibodies in AQP4 level test of Inflammation/autoimmune/inflammatory disease (Cerebrovascular diseases) and related syndrome evaluation.

Heparin-binding protein (HBP)

Cat No.	Species	Biomarker	Disease	Cat No.of Antigen	Bioactivity validation of Antigen	Cat No.of Antibodies	Bioactivity validation of Antibodies	Order
GMP-h-HBP	Human	Heparin-binding protein (HBP)	inflammation/autoimmune/ inflammatory disease	GMP-h-HBP-Ag01: Recombinant human HBP Protein	Heparin-binding protein (HBP) antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests,and other immunoassays as control material in HBP level test of Inflammation/autoimmune/inflammatory disease(inflammation/autoimmune/ inflammatory disease) and related syndrome evaluation.	GMP-h-HBP-Ab01; GMP-h-HBP-Ab02: Anti-human HBP mouse monoclonal antibody(mAb)	Human Heparin-binding protein (HBP) antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other Heparin-binding protein (HBP) antibodies in HBP level test of Inflammation/autoimmune/inflammatory disease (inflammation/autoimmune/ inflammatory disease) and related syndrome evaluation.

myelin oligodendrocyte glycoprotein (MOG)

Cat No.	Species	Biomarker	Disease	Cat No.of Antigen	Bioactivity validation of Antigen	Cat No.of Antibodies	Bioactivity validation of Antibodies	Order
GMP-h-MOG	Human	myelin oligodendrocyte glycoprotein (MOG)	MOG antibody disease	GMP-h-MOG-Ag01: Recombinant human MOG Protein	myelin oligodendrocyte glycoprotein (MOG) antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests,and other immunoassays as control material in MOG level test of Inflammation/autoimmune/inflammatory disease(MOG antibody disease) and related syndrome evaluation.	GMP-h-MOG-Ab01; GMP-h-MOG-Ab02: Anti-human MOG mouse monoclonal antibody(mAb)	Human myelin oligodendrocyte glycoprotein (MOG) antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other myelin oligodendrocyte glycoprotein (MOG) antibodies in MOG level test of Inflammation/autoimmune/inflammatory disease (MOG antibody disease) and related syndrome evaluation.

Calprotectin heavy chain (S100-A9)

Cat No.	Species	Biomarker	Disease	Cat No.of Antigen	Bioactivity validation of Antigen	Cat No.of Antibodies	Bioactivity validation of Antibodies	Order
GMP-h-S100-A9	Human	Calprotectin heavy chain (S100-A9)	inflammatory bowel disease	GMP-h-S100-A9-Ag01: Recombinant human S100-A9 Protein	Calprotectin heavy chain (S100-A9) antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests,and other immunoassays as control material in S100-A9 level test of Inflammation/autoimmune/inflammatory disease(inflammatory bowel disease) and related syndrome evaluation.	GMP-h-S100-A9-Ab01; GMP-h-S100-A9-Ab02: Anti-human S100-A9 mouse monoclonal antibody(mAb)	Human Calprotectin heavy chain (S100-A9) antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other Calprotectin heavy chain (S100-A9) antibodies in S100-A9 level test of Inflammation/autoimmune/inflammatory disease (inflammatory bowel disease) and related syndrome evaluation.

Thyroid peroxidase (TPO)

Cat No.	Species	Biomarker	Disease	Cat No.of Antigen	Bioactivity validation of Antigen	Cat No.of Antibodies	Bioactivity validation of Antibodies	Order
GMP-h-TPO	Human	Thyroid peroxidase (TPO)	Hashimoto's disease or Graves' disease	GMP-h-TPO-Ag01: Recombinant human TPO Protein	Thyroid peroxidase (TPO) antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests,and other immunoassays as control material in TPO level test of Inflammation/autoimmune/inflammatory disease(Hashimoto's disease or Graves' disease) and related syndrome evaluation.	GMP-h-TPO-Ab01; GMP-h-TPO-Ab02: Anti-human TPO mouse monoclonal antibody(mAb)	Human Thyroid peroxidase (TPO) antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other Thyroid peroxidase (TPO) antibodies in TPO level test of Inflammation/autoimmune/inflammatory disease (Hashimoto's disease or Graves' disease) and related syndrome evaluation.

Serum Amyloid A1 (SAA1)

Cat No.	Species	Biomarker	Disease	Cat No.of Antigen	Bioactivity validation of Antigen	Cat No.of Antibodies	Bioactivity validation of Antibodies	Order
GMP-h-SAA1	Human	Serum Amyloid A1 (SAA1)	Inflammatory amyloidosis	GMP-h-SAA1-Ag01: Recombinant human SAA1 Protein	Serum Amyloid A1 (SAA1) antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests,and other immunoassays as control material in SAA1 level test of Inflammation/autoimmune/inflammatory disease(Inflammatory amyloidosis) and related syndrome evaluation.	GMP-h-SAA1-Ab01; GMP-h-SAA1-Ab02: Anti-human SAA1 mouse monoclonal antibody(mAb)	Human Serum Amyloid A1 (SAA1) antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other Serum Amyloid A1 (SAA1) antibodies in SAA1 level test of Inflammation/autoimmune/inflammatory disease (Inflammatory amyloidosis) and related syndrome evaluation.

tumor necrosis factor alpha (TNFα)

Cat No.	Species	Biomarker	Disease	Cat No.of Antigen	Bioactivity validation of Antigen	Cat No.of Antibodies	Bioactivity validation of Antibodies	Order
GMP-h-TNFα	Human	tumor necrosis factor alpha (TNFα)	rheumatoid arthritis, ankylosing spondylitis, and Crohn’s disease	GMP-h-TNFα-Ag01: Recombinant human TNFα Protein	tumor necrosis factor alpha (TNFα) antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests,and other immunoassays as control material in TNFα level test of Inflammation/autoimmune/inflammatory disease(rheumatoid arthritis, ankylosing spondylitis, and Crohn’s disease) and related syndrome evaluation.	GMP-h-TNFα-Ab01; GMP-h-TNFα-Ab02: Anti-human TNFα mouse monoclonal antibody(mAb)	Human tumor necrosis factor alpha (TNFα) antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other tumor necrosis factor alpha (TNFα) antibodies in TNFα level test of Inflammation/autoimmune/inflammatory disease (rheumatoid arthritis, ankylosing spondylitis, and Crohn’s disease) and related syndrome evaluation.

mycophenolic acid (MPA)

Cat No.	Species	Biomarker	Disease	Cat No.of Antigen	Bioactivity validation of Antigen	Cat No.of Antibodies	Bioactivity validation of Antibodies	Order
GMP-SMT-MPA	Human	mycophenolic acid (MPA)	autoimmune disease	GMP-SMT-MPA-Ag01: BSA-mycophenolic acid (MPA); GMP-SMT-MPA-Ag02: OVA-mycophenolic acid (MPA)	Competitive immunoassay-validated hapten-carrier conjugates [BSA-&OVA-mycophenolic acid (MPA)], mycophenolic acid (MPA) antibodies binding, Immunogen in Competitive immunoassay validation, Elisa, lateral-flow tests,and other immunoassays as control material in MPA level test of Inflammation/autoimmune/inflammatory disease (autoimmune disease) and related syndrome evaluation.	GMP-SMT-MPA-Ab01: Anti-mycophenolic acid (MPA) mouse monoclonal antibody(mAb)	Human mycophenolic acid (MPA) binding, in Competitive immunoassay validation, Elisa, lateral-flow tests, and other immunoassays in MPA level test of Inflammation/autoimmune/inflammatory disease (autoimmune disease) and related syndrome evaluation.

cyclic citrullinated peptide (CCP)

Cat No.	Species	Biomarker	Disease	Cat No.of Antigen	Bioactivity validation of Antigen	Cat No.of Antibodies	Bioactivity validation of Antibodies	Order
GMP-SMT-CCP	Human	cyclic citrullinated peptide (CCP)	rheumatoid arthritis	GMP-SMT-CCP-Ag01: BSA-cyclic citrullinated peptide (CCP); GMP-SMT-CCP-Ag02: OVA-cyclic citrullinated peptide (CCP)	Competitive immunoassay-validated hapten-carrier conjugates [BSA-&OVA-cyclic citrullinated peptide (CCP)], cyclic citrullinated peptide (CCP) antibodies binding, Immunogen in Competitive immunoassay validation, Elisa, lateral-flow tests,and other immunoassays as control material in CCP level test of Inflammation/autoimmune/inflammatory disease (rheumatoid arthritis) and related syndrome evaluation.	GMP-SMT-CCP-Ab01: Anti-cyclic citrullinated peptide (CCP) mouse monoclonal antibody(mAb)	Human cyclic citrullinated peptide (CCP) binding, in Competitive immunoassay validation, Elisa, lateral-flow tests, and other immunoassays in CCP level test of Inflammation/autoimmune/inflammatory disease (rheumatoid arthritis) and related syndrome evaluation.

alpha defensin 1 (α-defensin 1)

Cat No.	Species	Biomarker	Disease	Cat No.of Antigen	Bioactivity validation of Antigen	Cat No.of Antibodies	Bioactivity validation of Antibodies	Order
GMP-h-a-defensin-1	Human	alpha defensin 1 (α-defensin 1)	Prosthetic joint infection (PJI)	GMP-h-a-defensin-1-Ag01: Recombinant Human α-defensin 1 Protein	alpha defensin 1 (α-defensin 1) antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in α-defensin 1 level test of Inflammation/autoimmune/inflammatory disease (Prosthetic joint infection (PJI)) and related syndrome evaluation	GMP-h-a-defensin-1-Ab01: GMP-h-a-defensin-1-Ab02: Anti-Human α-defensin 1 mouse monoclonal antibody (mAb)	Human alpha defensin 1 (α-defensin 1) antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other alpha defensin 1 (α-defensin 1) antibodies in α-defensin 1 level test of Inflammation/autoimmune/inflammatory disease (Prosthetic joint infection (PJI)) and related syndrome evaluation.

alpha defensin 5 (α-defensin 5)

Cat No.	Species	Biomarker	Disease	Cat No.of Antigen	Bioactivity validation of Antigen	Cat No.of Antibodies	Bioactivity validation of Antibodies	Order
GMP-h-a-defensin-5	Human	alpha defensin 5 (α-defensin 5)	Prosthetic joint infection (PJI)	GMP-h-a-defensin-5-Ag01: Recombinant Human α-defensin 5 Protein	alpha defensin 5 (α-defensin 5) antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in α-defensin 5 level test of Inflammation/autoimmune/inflammatory disease (Prosthetic joint infection (PJI)) and related syndrome evaluation	GMP-h-a-defensin-5-Ab01: GMP-h-a-defensin-5-Ab02: Anti-Human α-defensin 5 mouse monoclonal antibody (mAb)	Human alpha defensin 5 (α-defensin 5) antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other alpha defensin 5 (α-defensin 5) antibodies in α-defensin 5 level test of Inflammation/autoimmune/inflammatory disease (Prosthetic joint infection (PJI)) and related syndrome evaluation.

GeneMedi’s IL-6 (Interleukin 6) Antibody Pair Validation In Sandwich ELISA     Data Post Download

Figure. GeneMedi's IL-6 antibody pair validation with IL-6 antigen (IL-6-Ag01) in sandwich ELISA.

Abbreviation	Description
IL-6-Ab01	GMP-h-IL-6-Ab01
IL-6-Ab02	GMP-h-IL-6-Ab02
IL6-Ab03	GMP-h-IL6-Ab03
IL-6-Ag01	GMP-h-IL-6-Ag01

GeneMedi’s PCT (procalcitonin) Antibody Pair Validation In Sandwich ELISA     Data Post Download

Figure. GeneMedi's PCT antibody pair validation with PCT antigen (PCT-Ag01) in sandwich ELISA.

Abbreviation	Description
PCT-Ab01	GMP-h-PCT-Ab01
PCT-Ab02	GMP-h-PCT-Ab02
PCT-Ag01	GMP-h-PCT-Ag01