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Diagnostic antibodies and antigens list


Diagnostic Inflammation
Diagnostic Tumor
Diagnostic kidney function (renal damages)
Diagnostic Neuropathy
Diagnostic Autoimmune Disease
Diagnostic Epilepsy
Diagnostic Pain-releated
Diagnostic Infectious Disease
Diagnostic Bone Metabolism
Diagnostic Liver Diseases Fibrosis
Diagnostic Gastric Disease
Diagnostic Hypertension
Diagnostic Thyroid Disease
Diagnostic Cardiovascular Disease
Food Safety Testing
Diagnostic Fertility-releated
Diagnostic Diabetes
Diagnostic Chronic Atrophic Gastritis
Diagnostic Hormone Disorders


Diagnostic antibodies and antigens for inflammation and cytokine release syndrome (CRS) testing-PCT, CRP, IL-6, SAA

Cytokine release syndrome (CRS) is an acute systemic inflammatory syndrome characterized by fever and multiple organ dysfunction.

Genemedi produces core diagnostic ingredients for rapid test kit of systemic inflammation and CRS caused by infectious diseases or sepsis-related organ failure.

GeneMedi offers paired antibodies (monoclonal antibody,mab)and antigens of inflammatory syndrome and cytokine release syndrome (CRS) biomarkers including: procalcitonin (PCT) antigens and paired antibodies(anti-PCT), C-reactive protein (CRP)antigens and paired antibodies(anti-CRP), Serum amyloid A protein(SAA)antigens and paired antibodies(anti-SAA), interleukin-6 (IL-6) antigens and paired antibodies(anti-IL6 or anti-IL-6) and so on.



Diagnostic antibodies and antigens for infectious disease testing including HIV/AIDS, HCV, Influenza A/B, Syphilis, Helicobacter pylori, HSV-1/2, CMV, rubella virus, toxoplasma

Infectious diseases caused by living organisms like viruses and bacteria are hamful to human body.

Genemedi produces core diagnostic ingredients for test of infectious diseases and related syndrome.

GeneMedi offers paired diagnostics grade antibodies (monoclonal antibody,mab)and antigens for infectious disease rapid test kit including infection of HIV/AIDS,Hepatitis C virus(HCV), Influenza A/B,Treponema Pallidum caused Syphilis, Helicobacter pylori (H. pylori) Bacteria, Herpes simplex virus 1/2(HSV-1/HSV-2), Cytomegalovirus (CMV), rubella virus, toxoplasma gondii and so on.



Diagnostic antibodies and antigens for Heart disease & Cardiovascular disease biomarkers testing

Cardiovascular biomarkers play an essential role in the diagnosis, risk stratification and treatment of patients with cardiac diseases including acute myocardial infarction, cardiac fibrosis and heart failure.

Genemedi produces core diagnostic ingredients for test of heart diseases and related syndrome.

GeneMedi offers paired antibodies (monoclonal antibody,mab) and antigens of cardiac biomarkers for diagnostics of cardiovascular disease and heart injury including: Myeloperoxidase (MPO) antigens and paired antibodies(anti-MPO), matrix metalloproteinase-3 (MMP3)antigens and paired antibodies(anti-MMP3), Growth differentiation factor-15 (GDF-15) antigens and paired antibodies(anti-GDF15), Creatine Kinase MB (CK-MB) antigens and paired antibodies(anti-CK-MB), Myoglobin (Myo) antigens and paired antibodies(anti-Myoglobin), soluble ST2 (sST2) antigens and paired antibodies(anti-sST2) and so on.



Diagnostic antibodies and antigens for tumor detection

Regardless of the advances in the cancer therapy, delayed symptoms and lack of successful diagnosis of cancer at early stage increased the death rate. Tumor-associated antigens (TAAs) and their antibodies have been identified as potential markers in cancer diagnosis and determination. TAAs and their antibodies-based detection of cancer have the advantages such as low-cost, and simple access, which attracted much attention for early cancer detection. For several reasons, tumor marker itself is typically insufficient to analyze disease conditions. Because, maximum number of markers have been produced by both normal and cancer cells. Several markers such as hyroglobulin (TG), cancer antigen 125 (CA-125), squamous cell carcinoma antigen (SCC Ag), Protein induced by vitamin K absence-II (PIVKA-II), Gastrin-releasing peptide (Pro-GRP), Calcitonin, Neuron specific enolase (NSE), Cancer Antigen 72-4 (CA-724), Human epididymis protein 4 (HE4), Cancer antigen 15-3 (CA15-3), cytokeratin-19 (CYFRA21-1), human epidermal growth factor receptor 2 (HER2), Ferritin (FER), Heat shock proteins 90-alpha (HSP90α), S100 proteins (S100B) and so on have been identified to be associated with the specific cancer. Detecting the quantity of these marker proteins from different samples may benefit from ELISA, Lateral flow immunoassay (LFIA), colloidal gold immunochromatographic assay, Chemiluminescent immunoassay (CLIA), turbidimetric inhibition immuno assay (TINIA), immunonephelometry and POCT.



Diagnostic antibodies and antigens for Bone metabolism testing: PINP, β-CTx, 25-OH-VD, 25-OH-(VD3+VD2)

Calcium homeostasis depends on the reabsorption of bone by osteoclasts and the development of bone by osteoblasts. Imbalance between these two metabolisms leads to osteoporosis. Osteoporosis is a health condition characterized by low bone density, making them fragile and more risk of bone fracture. Osteoporosis develops gradually over several years and is often diagnosed by the sudden impact of bone fracture. Thus, the mechanisms that control communication between osteoclasts and osteoblasts are important for the bone metabolism.  The etiology of osteoporosis is related to hormonal factors, the use of certain drugs (eg, glucocorticoids), cigarette smoking, low physical activity, low intake of calcium and vitamin D, race, small body size, and a personal or a family history of fracture. Biochemical markers of tissue turnover are increasingly used for the early diagnosis of the osteoporosis. In addition, such markers may provide additional information for understanding the pathology of disease. Several markers such as amino-terminal propeptide (PINP), β-isomerized C-terminal telopeptides, 25-hydroxy (OH) Vitamin (25-OH-VD), 25 hydroxyvitamin D and so on have been identified to be associated with the bone metabolism and osteoporosis. Detecting the quantity of these marker proteins from different samples may benefit from ELISA, Lateral flow immunoassay (LFIA), colloidal gold immunochromatographic assay, Chemiluminescent immunoassay (CLIA), turbidimetric inhibition immuno assay (TINIA), immunonephelometry and POCT.



Diagnostic antibodies and antigens for food safety testing in mycotoxin and chemical contamination

Food control and testing is carried out globally due to its public health importance. Food items have a long process from their production to processing and delivery. Several chemicals such as pesticides and preservatives are used during production and processing. In addition, Mycotoxin contamination by the fungus is considered an inevitable and unpredictable problem. The possibility of mycotoxin contamination by the fungus can be developed in any stages from the crop production to processing. Hence, the food safety tests have to be performed in an accredited testing laboratory to ensure the food safety before marketing. The conventional testing methods are limited by sophisticated sample preparation procedures, analysis time, large instruments and professionals. Thus, rapid testing of food safety system is a potential way to fasten the food testing.

GENEMEDI developed the antigens and antibodies for rapid kit such as Competitive immunoassay validation (Competitive ELISA) with hapten-carrier conjugates and anti-Hapten antibody, and Lateral flow immunoassay (LFIA) to detect the antibiotics, food safety components, agricultural residues, allergen, mycotoxins, drugs of abuse, toxic heavy metal, hormones, chemicals, vitamins, amino acids and so on.



Diagnostic antibodies and antigens for Liver Diseases/Fibrosis testing: Hyaluronic acid (HA), laminins (LN), collagen type IV (cIV), Procollagen III N-terminal peptide (PIIINP)

The Kidneys are important to filter wastes and excess fluids from the blood and excreted in urine. Chronic kidney disease steadily loss the kidney function and fail to filter the waste in the body. The chronic kidney disease (CKD) includes advanced stage of renal parenchyma damage and the loss of functional nephrons. The loss of functional nephrons induces several molecular and cellular events, which leads to the development of renal lesions. The chronic kidney disease disperses the podocytes from basal membrane and excrete in the urine, therefore the diagnosis usually made with the serum proteins (creatinine) and blood urea (sCr). The early diagnosis of this disease is an important step to prevent the CKD. Biomarker such as Cystatin C (CYSC) Neutrophil gelatinase-associated lipocalin (NGAL), Beta-2 microglobulin (B2M), Alpha-1-microglobulin (A1M) and so on are suitable for monitoring CKD at early stages. Detecting the quantity of these marker proteins from different samples may benefit from ELISA, Lateral flow immunoassay (LFIA), colloidal gold immunochromatographic assay, Chemiluminescent immunoassay (CLIA), turbidimetric inhibition immuno assay (TINIA), immunonephelometry and POCT.



Diagnostic antibodies and antigens for Liver Diseases/Fibrosis testing: Hyaluronic acid (HA), laminins (LN), collagen type IV (cIV), Procollagen III N-terminal peptide (PIIINP)

Liver is an important organ and it is responsible for the metabolism, energy storage, and waste filtering. Liver disease is a generally designates to any condition that affects the liver. These conditions may be because of different reasons, but all these reasons damage the liver and affect its function. Many people with liver disease do not cause any symptoms in the early stages. At a certain point in the development of liver disease damage can become irreversible and lead to liver failure, liver cancer, or death. Early diagnosis of liver disease may prevent liver damage.

GENEMEDI produces core diagnostic ingredients such as Hyaluronic acid binding protein (HABP); laminins (LN); collagen type IV (cIV); Procollagen III N-terminal peptide and so on for test of Liver Diseases/Fibrosis and related syndrome using ELISA, Lateral flow immunoassay (LFIA), colloidal gold immunochromatographic assay, Chemiluminescent immunoassay (CLIA), turbidimetric inhibition immuno assay (TINIA), immunonephelometry and POCT Kit.



Diagnostic antibodies and antigens for Fertility testing: Anti-Mullerian hormone (AMH), Fetal fibronectin (fFN)

The pregnancy contains multiple steps that must effectively happen at a precise time and in the precise place. For fertilization, oocytes and sperm cells must experience a series of differentiation and development process. Abnormalities on the placement of embryo in the woman’s uterus, decidualization, placentation and intrauterine embryonic development consequence the onset of pre-eclampsia, miscarriage and/or preterm birth. On the other hand, sperm cells of the man should undergo capacitation and acrosome exocytosis to fertilize oocytes appropriately. A little imbalance in this process may disturb the capability of sperm cells to fertilize the egg. Thus, the detection of biomarkers to monitor the pregnancy process, and complication in both female and male gametes is an opportunity for successful pregnancy. Recently, several biomarkers have been developed to improve diagnostic accuracy. Indeed, GENEMEDI offer the biomarkers such as Anti-Mullerian hormone (AMH), Fetal fibronectin (fFN) and so on to make a successful pregnancy. Detecting the quantity of these marker proteins from different samples may benefit from ELISA, Lateral flow immunoassay (LFIA), colloidal gold immunochromatographic assay, Chemiluminescent immunoassay (CLIA), turbidimetric inhibition immuno assay (TINIA), immunonephelometry and POCT.



Diagnostic antibodies and antigens for Fertility testing: Anti-Mullerian hormone (AMH), Fetal fibronectin (fFN)

Neuropathy refers to the injury or dysfunction of one or more nerves, which results in numbness, tingling, muscle weakness and discomfort in the nerves affected part. Neuropathies often arise from the hands and feet, sometimes other parts of the body also affected. Peripheral neuropathy refers the injury or dysfunction of the peripheral nerves.  Peripheral neuropathy might be acute or chronic, and sometimes it is reversible. Neuropathy induces a series of complications in the health and develop the symptoms of those issues. Biochemical markers are increasingly used for the early diagnosis of the neuropathy. In addition, such markers may provide additional information for understanding the pathology of disease. Several markers such as a tau protein (tau), Phospho-tau181 (p-tau181), Phospho-tau217 (p-tau217), neurofilament light chain (NFL) and so on have been identified to be associated with the neuropathy disorder. Detecting the quantity of these marker proteins from different samples may benefit from ELISA, Lateral flow immunoassay (LFIA), colloidal gold immunochromatographic assay, Chemiluminescent immunoassay (CLIA), turbidimetric inhibition immuno assay (TINIA), immunonephelometry and POCT.



Diagnostic antibodies and antigens for gastric disease testing: PG I, PG II

Gastric cancer is the fifth most common disease leads to the death. Most death of gastric cancer is mostly due the diagnosis at late-stage. The diagnosis of Gastric cancer at early-stage is delayed due to the lack symptoms and effective diagnostic technique. The traditional technology, including endoscopic examination and gastroscopic biopsy are invasive to screen large population. Hence, biomarkers such as pepsinogen I (PG I), Pepsinogen II (PG II) and so on have been developed to detect the gastric cancer at an early stage for large population to significantly reduce the death caused by gastric cancer. However, the detection of these marker proteins from different samples may benefit from ELISA, Lateral flow immunoassay (LFIA), colloidal gold immunochromatographic assay, Chemiluminescent immunoassay (CLIA), turbidimetric inhibition immuno assay (TINIA), immunonephelometry and POCT.



Diagnostic antibodies and antigens for diabetes testing: C-Peptide

Diabetes mellitus is the most known chronic disorder characterized by hyperglycemia. Diabetes mellitus is classified based on the deficiency of insulin production due to β-cell destruction (type 1) and by increased insulin resistance (type 2). The increasing rate of obesity increased the difficulties to determine the type of diabetes mellitus. The classification of diabetes mellitus is important for treatment. Beside the conventional method, the detection of biomarkers such as C-peptide reflects insulin secretion from pancreatic β cells and differentiate the diabetes mellitus type. However, the detection of these marker proteins from different samples may benefit from ELISA, Lateral flow immunoassay (LFIA), colloidal gold immunochromatographic assay, Chemiluminescent immunoassay (CLIA), turbidimetric inhibition immuno assay (TINIA), immunonephelometry and POCT.



Diagnostic antibodies and antigens for autoimmune disease testing

Autoimmune diseases occur when the immune system attacks the normal tissue within joints, vasculature, and other organ systems, causing inflammation, pain, diminished mobility, fatigue, and other non-specific symptoms.1 The strong overlap of signs and symptoms among the autoimmune diseases can lead to delays in diagnosis and appropriate treatment. However, immunodiagnostics has been developed to detect the autoimmune disease at an early stage. biomarkers such as Mycophenolic acid (MPA) and Cyclic citrullinated peptide (CCP) and so on have been developed to detect the autoimmune disease at an early stage of organ transplantation and rheumatoid arthritis, respectively.

GENEMEDI developed the antigens and antibodies for rapid kit such as Competitive immunoassay validation (Competitive ELISA) with hapten-carrier conjugates and anti-Hapten antibody, and Lateral flow immunoassay (LFIA) to detect the autoimmune disease.



Diagnostic antibodies and antigens for pain-related testing: acetaminophen (Paracetamol) toxicity

Acetaminophen is known as paracetamol in many countries outside the US. It is one of the most frequently used oral analgesics and antipyretics. It has an outstanding safety profile when administered in an appropriate dose, but hepatotoxicity can occur after overdose or when misused in at-risk populations.

GENEMEDI developed the antigens and antibodies for the diagnosis of potential acetaminophen toxicity based on ELISA, Lateral flow immunoassay (LFIA), colloidal gold immunochromatographic assay, Chemiluminescent immunoassay (CLIA), turbidimetric inhibition immuno assay (TINIA), immunonephelometry and POCT.



Diagnostic antibodies and antigens for Chronic atrophic gastritis testing

Chronic atrophic gastritis (CAG) with intestinal metaplasia is recognized to be a precancerous lesion that can evolve toward low- and high-grade intraepithelial lesions and gastric cancer. CAG is characterized by loss of gastric glands and can be evaluated endoscopically, histologically and serologically. Therefore, its early detection is a priority in preventing gastric cancer. Hence, biomarkers such as Gastrin-17 (G-17) and so on have been developed to detect the chronic atrophic gastritis at an early stage to significantly reduce the gastric cancer.

GENEMEDI developed the Gastrin-17 (G-17) antigens and antibodies for the diagnosis of chronic atrophic gastritis based on ELISA, Lateral flow immunoassay (LFIA), colloidal gold immunochromatographic assay, Chemiluminescent immunoassay (CLIA), turbidimetric inhibition immuno assay (TINIA), immunonephelometry and POCT.



Diagnostic antibodies and antigens for Epilepsy-related testing: Sodium valproate (VPA) valproate (VPA) toxicity

Valproate is a commonly used antiepileptic drug for the treatment of epilepsy and seizures. It is safe for use in both adults and children more than three years of age. Valproate toxicity can occur both accidentally and intentionally. Acute valproate overdose usually presents with CNS depression/encephalopathy, electrolyte abnormalities such as hypernatremia, elevated transaminase levels, hyperammonemia, and hepatoxicity. In patients with a severe overdose of valproate, patients can present with hypotension, tachycardia, respiratory depression, metabolic acidosis, cerebral edema, and valproate-related hyperammonemic encephalopathy which may progress to coma and death.

GENEMEDI developed the Gastrin-17 (G-17) antigens and antibodies for the diagnosis of valproate toxicity based on ELISA, Lateral flow immunoassay (LFIA), colloidal gold immunochromatographic assay, Chemiluminescent immunoassay (CLIA), turbidimetric inhibition immuno assay (TINIA), immunonephelometry and POCT.



Diagnostic antibodies and antigens for Hypertension testing: aldosterone (RAA/Aldo)

High blood pressure (hypertension) is a common disorder. it may eventually cause health problems, such as heart disease. Subgroups of the patients have been identified on the basis of their responses to hormonal and biologic stimuli. These subgroups include low-renin hypertensives and nonmodulators. Aldosterone, the principal human mineralocorticoid, which control blood pressure by holding onto salt and losing potassium from the blood. The increased salt increases the blood pressure. Hyperaldosteronism is a disease in which the adrenal gland(s) make too much aldosterone which leads to hypertension and low blood potassium levels.

GENEMEDI offers Diagnostic hapten-carrier conjugates BSA-aldosterone (RAA/Aldo), OVA-aldosterone (RAA/Aldo), KLH-aldosterone (RAA/Aldo) for Hypertension RAA/Aldo detection in Competitive immunoassay validation (Competitive ELISA), Lateral flow immunoassay (LFIA), colloidal gold immunochromatographic assay, Chemiluminescent immunoassay (CLIA), turbidimetric inhibition immuno assay (TINIA), immunonephelometry and POCT. All the antibodies and antigens for Hypertension test are suitable for in functional ELISA, and other immunoassays in diagnostics.



Diagnostic antibodies and antigens for Hormone disorders testing: dehydroepiandrosterone (DHEA)

Hormonal imbalances occur when there is too much or too little of a hormone in the bloodstream. Because of their essential role in the body, even slight hormonal imbalances can cause side effects throughout the body. Dehydroepiandrosterone (DHEA), also known as androstenolone, is an endogenous steroid hormone precursor. It is one of the most abundant circulating steroids in humans. DHEA is produced in the adrenal glands, the gonads, and the brain. It functions as a metabolic intermediate in the biosynthesis of the androgen and estrogen sex steroids both in the gonads and in various other tissues. DHEA(S) and related steroids have been shown to have potent effects on immunological function. Changes in levels of DHEA or in the cortisol/DHEA ratio have been associated with the pathophysiology of depression, atherosclerotic disease, obesity, hyperinsulinemia, and inflammatory disease.

GeneMedi offers diagnostic antibody to detect the level of DHEA.



Diagnostic antibodies and antigens for Thyroid disease testing: Reverse triiodothyronine (rT3)

Thyroid gland produces the hormones that keep body functioning normally. When concentration of these hormone increases or decrease, it’s called a thyroid disease. There are several types of thyroid disease, which includes hyperthyroidism, hypothyroidism, thyroiditis and Hashimoto’s thyroiditis. The most commonly measured thyroid hormones are thyroid stimulating hormone (TSH), total thyroxine (T4), free T4, total triiodothyronine (T3), and free T3. The thyroid gland produces T4, as well as some T3. After its release from the thyroid gland, T4 is converted to T3, which is an active thyroid hormone, or to Reverse triiodothyronine (rT3), which is considered an inactive form. The rate and ratio of T4 conversion to either T3 or rT3 is depends upon the body's metabolic requirement. Hence, the measurement of rT3 is useful to diagnose the thyroid disorder.

GeneMedi offers diagnostic antibody to detect the level of reverse triiodothyronine (rT3).






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