GeneMedi SOLIDEX™ Cell Therapy Solutions

GeneMedi SOLIDEX™ Cell Therapy Solutions

GeneMedi offers a comprehensive one-stop solution covering cell separation, flow cytometry analysis, and CAR-T cell therapy development, empowering precision medicine research and clinical translation.



SOLIDEX™ Cell Therapy Solutions Detail

ISOEx Immunocytes Cell Isolation Immunomagnetic Beads

Function: High-purity enrichment of specific immune cells or stem cells for downstream experiments.

Product Highlights:

  • Optimized antibodies targeting CD3, CD4, CD8, CD14, CD19, CD34, NK (CD56), monocytes (CD14), and more.

Core Technologies:

Category Type Description Advantages Disadvantages
Labeling Method Direct cell isolation Antibodies directly conjugated to magnetic beads Fastest method (single-step)
High specificity
Simple protocol
Limited flexibility
High capacity to antibodies
Indirect cell isolation Uses biotinylated secondary capture (reusable beads) Antibody flexibility
Cost-effective
Signal amplification possible
Longer protocol
Potential for higher background
Additional step required
Bead Type Releasable Allow competitive elution Better for sensitive applications
Simple workflow
More expensive beads
May interfere with some tasks
Non-releasable Form irreversible bonds (Streptavidin beads) Ideal for negative selection
More economical
Permanent bead attachment
Format Column-based Uses magnetic columns with 50nm beads Highest purity Requires columns
Slower processing
Higher cost
Column-free Uses larger beads with external magnets Fast processing (<15 min)
No column costs
Slightly lower purity
Less suitable for automation

Detail

CDEx Flow Cytometry Antibodies

Function: Multiplexed, high-sensitivity analysis of immune cell phenotypes at the single-cell level.

Product Portfolio:

  • PE/APC/FITC-Conjugated Antibodies: Targeting CD3E, CD4, CD8, CD14, CD19, NCAM1 (CD56), TCR αβ, and others.

  • Naked Antibodies: Support custom labeling (e.g., biotin, fluorescent dyes).

Technical Advantages:

  • Exceptional sensitivity and specificity for complex samples like PBMCs.

Detail

TAGEx CAR-Analytical Tools

Companion Detection Tools:

  • CAR-Specific Antibodies: Targeting scFv (e.g., FMC63), VHH, G4S nanobodies, hinge/transmembrane domains, and intracellular signaling motifs.

  • Quality Control: Simulated sample testing and reduced background signals (outperforms Company C).

Lentiviral Vector Services:

  • Target Proteins: CD19 (leukemia), BCMA (multiple myeloma), Her2 (breast cancer), GPC3 (hepatocellular carcinoma), etc.

  • Key Features: High transduction efficiency, low genotoxicity, and support for multi-gene payloads (≤6.5 kb).

Service Workflow:

  • Lentivirus packaging → CAR-T cell engineering → Functional validation → Preclinical/clinical trial support

Detail
Alzheimer's Disease (AD)

End-to-End Coverage

From cell isolation → phenotypic analysis → gene modification → functional validation.

Parkinson's Disease (PD)

Customization

Tailored solutions for antibody labeling, vector design, and target optimization.

Huntington's Disease (HD)

Synergy

Immunomagnetic bead-based purification enhances flow cytometry accuracy; lentiviral systems ensure efficient CAR-T production.

Huntington's Disease (HD)

Applications

Oncology immunotherapy, Autoimmune disease research, Rare disease modeling, CAR-T clinical pipeline development





SOLIDEX™ solution - Product list

  • ISOEx Immunocytes Cell Isolation Immunomagnetic Beads
  • CDEx Flow Cytometry antibodies
  • TAGEx CAR-Analytical Tools

Our magnetic bead-based cell isolation portfolio now offers six tailored configurations, combining three critical parameters to match diverse experimental needs: Labeling Type (Direct/Indirect) x Bead Type (Non-releasable/Releasable) x Format (Column/Column-free)

Choose from Biomarkers: CD66b, CD34, NCAM1 (CD56), CD14, CD19, CD3E, CD4, CD8, TCR alpha-beta (abT), CD138, CD45RA, CD45, CD16

Cat.No Product Name Labeling Type Bead Type Format Key Features Species Size Cell population Products Information
GM-Tg-hg-MP0250-iso-nanoIMBHuman CD66b Nano-mag BeadsDirectNon-releasableColumnFast isolation; high purity; ideal for automated workflowshuman1ml, 5ml, 10mlGranulocyteDetails
GM-Tg-hg-MP0250-iso-nanoIMB-CFHuman CD66b Column-Free Nano-mag BeadsDirectNon-releasableColumn-freeRapid processing; no column needed; perfect for quick experimentshuman1ml, 5ml, 10mlGranulocyteDetails
GM-Tg-hg-MP0250-iso-rel-kitReleasable Human CD66b+ Cell Isolation KitIndirectReleasableColumnGentle bead removal for sensitive cells; superior recoveryhuman1ml, 5ml, 10mlGranulocyteDetails
GM-Tg-hg-MP0250-iso-rel-kit-CFReleasable Human CD66b+ Cell Isolation Column-Free KitIndirectReleasableColumn-freeFlexible antibody combinations with fast bead removalhuman1ml, 5ml, 10mlGranulocyteDetails
GM-Tg-hg-MP0250-iso-kitIndirect Human CD66b+ Cell Isolation KitIndirectNon-releasableColumnPermanent binding; high-purity isolation for industrial applicationshuman1ml, 5ml, 10mlGranulocyteDetails
GM-Tg-hg-MP0250-iso-kit-CFIndirect Human CD66b+ Cell Isolation Column-Free KitIndirectNon-releasableColumn-freeCost-effective solution for standard cell selection/depletionhuman1ml, 5ml, 10mlGranulocyteDetails
GM-Tg-hg-T66426-iso-nanoIMBHuman CD34 Nano-mag BeadsDirectNon-releasableColumnFast isolation; high purity; ideal for automated workflowshuman1ml, 5ml, 10mlHematopoietic Stem CellDetails
GM-Tg-hg-T66426-iso-nanoIMB-CFHuman CD34 Column-Free Nano-mag BeadsDirectNon-releasableColumn-freeRapid processing; no column needed; perfect for quick experimentshuman1ml, 5ml, 10mlHematopoietic Stem CellDetails
GM-Tg-hg-T66426-iso-rel-kitReleasable Human CD34+ Cell Isolation KitIndirectReleasableColumnGentle bead removal for sensitive cells; superior recoveryhuman1ml, 5ml, 10mlHematopoietic Stem CellDetails
GM-Tg-hg-T66426-iso-rel-kit-CFReleasable Human CD34+ Cell Isolation Column-Free KitIndirectReleasableColumn-freeFlexible antibody combinations with fast bead removalhuman1ml, 5ml, 10mlHematopoietic Stem CellDetails
GM-Tg-hg-T66426-iso-kitIndirect Human CD34+ Cell Isolation KitIndirectNon-releasableColumnPermanent binding; high-purity isolation for industrial applicationshuman1ml, 5ml, 10mlHematopoietic Stem CellDetails
GM-Tg-hg-T66426-iso-kit-CFIndirect Human CD34+ Cell Isolation Column-Free KitIndirectNon-releasableColumn-freeCost-effective solution for standard cell selection/depletionhuman1ml, 5ml, 10mlHematopoietic Stem CellDetails
GM-Tg-hg-T86323-iso-nanoIMBHuman NCAM1 (CD56) Nano-mag BeadsDirectNon-releasableColumnFast isolation; high purity; ideal for automated workflowsmouse1ml, 5ml, 10mlNK cellDetails
GM-Tg-hg-T86323-iso-nanoIMB-CFHuman NCAM1 (CD56) Column-Free Nano-mag BeadsDirectNon-releasableColumn-freeRapid processing; no column needed; perfect for quick experimentsmouse1ml, 5ml, 10mlNK cellDetails
GM-Tg-hg-T86323-iso-rel-kitReleasable Human NCAM1 (CD56)+ Cell Isolation KitIndirectReleasableColumnGentle bead removal for sensitive cells; superior recoverymouse1ml, 5ml, 10mlNK cellDetails
GM-Tg-hg-T86323-iso-rel-kit-CFReleasable Human NCAM1 (CD56)+ Cell Isolation Column-Free KitIndirectReleasableColumn-freeFlexible antibody combinations with fast bead removalmouse1ml, 5ml, 10mlNK cellDetails
GM-Tg-hg-T86323-iso-kitIndirect Human NCAM1 (CD56)+ Cell Isolation KitIndirectNon-releasableColumnPermanent binding; high-purity isolation for industrial applicationsmouse1ml, 5ml, 10mlNK cellDetails
GM-Tg-hg-T86323-iso-kit-CFIndirect Human NCAM1 (CD56)+ Cell Isolation Column-Free KitIndirectNon-releasableColumn-freeCost-effective solution for standard cell selection/depletionmouse1ml, 5ml, 10mlNK cellDetails
GM-Tg-hg-T23212-iso-nanoIMBHuman CD14 Nano-mag BeadsDirectNon-releasableColumnFast isolation; high purity; ideal for automated workflowsmouse1ml, 5ml, 10mlMonocyte/MacrophageDetails
GM-Tg-hg-T23212-iso-nanoIMB-CFHuman CD14 Column-Free Nano-mag BeadsDirectNon-releasableColumn-freeRapid processing; no column needed; perfect for quick experimentsmouse1ml, 5ml, 10mlMonocyte/MacrophageDetails
GM-Tg-hg-T23212-iso-rel-kitReleasable Human CD14+ Cell Isolation KitIndirectReleasableColumnGentle bead removal for sensitive cells; superior recoverymouse1ml, 5ml, 10mlMonocyte/MacrophageDetails
GM-Tg-hg-T23212-iso-rel-kit-CFReleasable Human CD14+ Cell Isolation Column-Free KitIndirectReleasableColumn-freeFlexible antibody combinations with fast bead removalmouse1ml, 5ml, 10mlMonocyte/MacrophageDetails
GM-Tg-hg-T23212-iso-kitIndirect Human CD14+ Cell Isolation KitIndirectNon-releasableColumnPermanent binding; high-purity isolation for industrial applicationsmouse1ml, 5ml, 10mlMonocyte/MacrophageDetails
GM-Tg-hg-T23212-iso-kit-CFIndirect Human CD14+ Cell Isolation Column-Free KitIndirectNon-releasableColumn-freeCost-effective solution for standard cell selection/depletionmouse1ml, 5ml, 10mlMonocyte/MacrophageDetails
GM-Tg-hg-T56365-iso-nanoIMBHuman CD19 Nano-mag BeadsDirectNon-releasableColumnFast isolation; high purity; ideal for automated workflowsmouse1ml, 5ml, 10mlBcellDetails
GM-Tg-hg-T56365-iso-nanoIMB-CFHuman CD19 Column-Free Nano-mag BeadsDirectNon-releasableColumn-freeRapid processing; no column needed; perfect for quick experimentsmouse1ml, 5ml, 10mlBcellDetails
GM-Tg-hg-T56365-iso-rel-kitReleasable Human CD19+ Cell Isolation KitIndirectReleasableColumnGentle bead removal for sensitive cells; superior recoverymouse1ml, 5ml, 10mlBcellDetails
GM-Tg-hg-T56365-iso-rel-kit-CFReleasable Human CD19+ Cell Isolation Column-Free KitIndirectReleasableColumn-freeFlexible antibody combinations with fast bead removalmouse1ml, 5ml, 10mlBcellDetails
GM-Tg-hg-T56365-iso-kitIndirect Human CD19+ Cell Isolation KitIndirectNon-releasableColumnPermanent binding; high-purity isolation for industrial applicationsmouse1ml, 5ml, 10mlBcellDetails
GM-Tg-hg-T56365-iso-kit-CFIndirect Human CD19+ Cell Isolation Column-Free KitIndirectNon-releasableColumn-freeCost-effective solution for standard cell selection/depletionmouse1ml, 5ml, 10mlBcellDetails
GM-Tg-hg-T87075-iso-nanoIMBHuman CD3E Nano-mag BeadsDirectNon-releasableColumnFast isolation; high purity; ideal for automated workflowsmouse1ml, 5ml, 10mlPan-T cellDetails
GM-Tg-hg-T87075-iso-nanoIMB-CFHuman CD3E Column-Free Nano-mag BeadsDirectNon-releasableColumn-freeRapid processing; no column needed; perfect for quick experimentsmouse1ml, 5ml, 10mlPan-T cellDetails
GM-Tg-hg-T87075-iso-rel-kitReleasable Human CD3E+ Cell Isolation KitIndirectReleasableColumnGentle bead removal for sensitive cells; superior recoverymouse1ml, 5ml, 10mlPan-T cellDetails
GM-Tg-hg-T87075-iso-rel-kit-CFReleasable Human CD3E+ Cell Isolation Column-Free KitIndirectReleasableColumn-freeFlexible antibody combinations with fast bead removalmouse1ml, 5ml, 10mlPan-T cellDetails
GM-Tg-hg-T87075-iso-kitIndirect Human CD3E+ Cell Isolation KitIndirectNon-releasableColumnPermanent binding; high-purity isolation for industrial applicationsmouse1ml, 5ml, 10mlPan-T cellDetails
GM-Tg-hg-T87075-iso-kit-CFIndirect Human CD3E+ Cell Isolation Column-Free KitIndirectNon-releasableColumn-freeCost-effective solution for standard cell selection/depletionmouse1ml, 5ml, 10mlPan-T cellDetails
GM-Tg-hg-T10191-iso-nanoIMBHuman CD4 Nano-mag BeadsDirectNon-releasableColumnFast isolation; high purity; ideal for automated workflowsmouse1ml, 5ml, 10mlCD4-TDetails
GM-Tg-hg-T10191-iso-nanoIMB-CFHuman CD4 Column-Free Nano-mag BeadsDirectNon-releasableColumn-freeRapid processing; no column needed; perfect for quick experimentsmouse1ml, 5ml, 10mlCD4-TDetails
GM-Tg-hg-T10191-iso-rel-kitReleasable Human CD4+ Cell Isolation KitIndirectReleasableColumnGentle bead removal for sensitive cells; superior recoverymouse1ml, 5ml, 10mlCD4-TDetails
GM-Tg-hg-T10191-iso-rel-kit-CFReleasable Human CD4+ Cell Isolation Column-Free KitIndirectReleasableColumn-freeFlexible antibody combinations with fast bead removalmouse1ml, 5ml, 10mlCD4-TDetails
GM-Tg-hg-T10191-iso-kitIndirect Human CD4+ Cell Isolation KitIndirectNon-releasableColumnPermanent binding; high-purity isolation for industrial applicationsmouse1ml, 5ml, 10mlCD4-TDetails
GM-Tg-hg-T10191-iso-kit-CFIndirect Human CD4+ Cell Isolation Column-Free KitIndirectNon-releasableColumn-freeCost-effective solution for standard cell selection/depletionmouse1ml, 5ml, 10mlCD4-TDetails
GM-Tg-hg-TA040-iso-nanoIMBHuman CD8 Nano-mag BeadsDirectNon-releasableColumnFast isolation; high purity; ideal for automated workflowsmouse1ml, 5ml, 10mlCD8-TDetails
GM-Tg-hg-TA040-iso-nanoIMB-CFHuman CD8 Column-Free Nano-mag BeadsDirectNon-releasableColumn-freeRapid processing; no column needed; perfect for quick experimentsmouse1ml, 5ml, 10mlCD8-TDetails
GM-Tg-hg-TA040-iso-rel-kitReleasable Human CD8+ Cell Isolation KitIndirectReleasableColumnGentle bead removal for sensitive cells; superior recoverymouse1ml, 5ml, 10mlCD8-TDetails
GM-Tg-hg-TA040-iso-rel-kit-CFReleasable Human CD8+ Cell Isolation Column-Free KitIndirectReleasableColumn-freeFlexible antibody combinations with fast bead removalmouse1ml, 5ml, 10mlCD8-TDetails
GM-Tg-hg-TA040-iso-kitIndirect Human CD8+ Cell Isolation KitIndirectNon-releasableColumnPermanent binding; high-purity isolation for industrial applicationsmouse1ml, 5ml, 10mlCD8-TDetails
GM-Tg-hg-TA040-iso-kit-CFIndirect Human CD8+ Cell Isolation Column-Free KitIndirectNon-releasableColumn-freeCost-effective solution for standard cell selection/depletionmouse1ml, 5ml, 10mlCD8-TDetails
GM-Tg-hg-MP2610-iso-nanoIMBHuman TCR alpha-beta (abT) Nano-mag BeadsDirectNon-releasableColumnFast isolation; high purity; ideal for automated workflowshuman1ml, 5ml, 10mlAlpha-Beta T CellDetails
GM-Tg-hg-MP2610-iso-nanoIMB-CFHuman TCR alpha-beta (abT) Column-Free Nano-mag BeadsDirectNon-releasableColumn-freeRapid processing; no column needed; perfect for quick experimentshuman1ml, 5ml, 10mlAlpha-Beta T CellDetails
GM-Tg-hg-MP2610-iso-rel-kitReleasable Human TCR alpha-beta (abT)+ Cell Isolation KitIndirectReleasableColumnGentle bead removal for sensitive cells; superior recoveryhuman1ml, 5ml, 10mlAlpha-Beta T CellDetails
GM-Tg-hg-MP2610-iso-rel-kit-CFReleasable Human TCR alpha-beta (abT)+ Cell Isolation Column-Free KitIndirectReleasableColumn-freeFlexible antibody combinations with fast bead removalhuman1ml, 5ml, 10mlAlpha-Beta T CellDetails
GM-Tg-hg-MP2610-iso-kitIndirect Human TCR alpha-beta (abT)+ Cell Isolation KitIndirectNon-releasableColumnPermanent binding; high-purity isolation for industrial applicationshuman1ml, 5ml, 10mlAlpha-Beta T CellDetails
GM-Tg-hg-MP2610-iso-kit-CFIndirect Human TCR alpha-beta (abT)+ Cell Isolation Column-Free KitIndirectNon-releasableColumn-freeCost-effective solution for standard cell selection/depletionhuman1ml, 5ml, 10mlAlpha-Beta T CellDetails
GM-Tg-hg-T13017-iso-nanoIMBHuman CD138 Nano-mag BeadsDirectNon-releasableColumnFast isolation; high purity; ideal for automated workflowsmouse1ml, 5ml, 10mlPlasma CellDetails
GM-Tg-hg-T13017-iso-nanoIMB-CFHuman CD138 Column-Free Nano-mag BeadsDirectNon-releasableColumn-freeRapid processing; no column needed; perfect for quick experimentsmouse1ml, 5ml, 10mlPlasma CellDetails
GM-Tg-hg-T13017-iso-rel-kitReleasable Human CD138+ Cell Isolation KitIndirectReleasableColumnGentle bead removal for sensitive cells; superior recoverymouse1ml, 5ml, 10mlPlasma CellDetails
GM-Tg-hg-T13017-iso-rel-kit-CFReleasable Human CD138+ Cell Isolation Column-Free KitIndirectReleasableColumn-freeFlexible antibody combinations with fast bead removalmouse1ml, 5ml, 10mlPlasma CellDetails
GM-Tg-hg-T13017-iso-kitIndirect Human CD138+ Cell Isolation KitIndirectNon-releasableColumnPermanent binding; high-purity isolation for industrial applicationsmouse1ml, 5ml, 10mlPlasma CellDetails
GM-Tg-hg-T13017-iso-kit-CFIndirect Human CD138+ Cell Isolation Column-Free KitIndirectNon-releasableColumn-freeCost-effective solution for standard cell selection/depletionmouse1ml, 5ml, 10mlPlasma CellDetails
GM-Tg-hg-T43115-8-iso-nanoIMBHuman CD45RA Nano-mag BeadsDirectNon-releasableColumnFast isolation; high purity; ideal for automated workflowshuman1ml, 5ml, 10mlAllhematopoietic clsDetails
GM-Tg-hg-T43115-8-iso-nanoIMB-CFHuman CD45RA Column-Free Nano-mag BeadsDirectNon-releasableColumn-freeRapid processing; no column needed; perfect for quick experimentshuman1ml, 5ml, 10mlAllhematopoietic clsDetails
GM-Tg-hg-T43115-8-iso-rel-kitReleasable Human CD45RA+ Cell Isolation KitIndirectReleasableColumnGentle bead removal for sensitive cells; superior recoveryhuman1ml, 5ml, 10mlAllhematopoietic clsDetails
GM-Tg-hg-T43115-8-iso-rel-kit-CFReleasable Human CD45RA+ Cell Isolation Column-Free KitIndirectReleasableColumn-freeFlexible antibody combinations with fast bead removalhuman1ml, 5ml, 10mlAllhematopoietic clsDetails
GM-Tg-hg-T43115-8-iso-kitIndirect Human CD45RA+ Cell Isolation KitIndirectNon-releasableColumnPermanent binding; high-purity isolation for industrial applicationshuman1ml, 5ml, 10mlAllhematopoietic clsDetails
GM-Tg-hg-T43115-8-iso-kit-CFIndirect Human CD45RA+ Cell Isolation Column-Free KitIndirectNon-releasableColumn-freeCost-effective solution for standard cell selection/depletionhuman1ml, 5ml, 10mlAllhematopoietic clsDetails
GM-Tg-hg-T43115-iso-nanoIMBHuman CD45 Nano-mag BeadsDirectNon-releasableColumnFast isolation; high purity; ideal for automated workflowshuman1ml, 5ml, 10mlAllhematopoietic clsDetails
GM-Tg-hg-T43115-iso-nanoIMB-CFHuman CD45 Column-Free Nano-mag BeadsDirectNon-releasableColumn-freeRapid processing; no column needed; perfect for quick experimentshuman1ml, 5ml, 10mlAllhematopoietic clsDetails
GM-Tg-hg-T43115-iso-rel-kitReleasable Human CD45+ Cell Isolation KitIndirectReleasableColumnGentle bead removal for sensitive cells; superior recoveryhuman1ml, 5ml, 10mlAllhematopoietic clsDetails
GM-Tg-hg-T43115-iso-rel-kit-CFReleasable Human CD45+ Cell Isolation Column-Free KitIndirectReleasableColumn-freeFlexible antibody combinations with fast bead removalhuman1ml, 5ml, 10mlAllhematopoietic clsDetails
GM-Tg-hg-T43115-iso-kitIndirect Human CD45+ Cell Isolation KitIndirectNon-releasableColumnPermanent binding; high-purity isolation for industrial applicationshuman1ml, 5ml, 10mlAllhematopoietic clsDetails
GM-Tg-hg-T43115-iso-kit-CFIndirect Human CD45+ Cell Isolation Column-Free KitIndirectNon-releasableColumn-freeCost-effective solution for standard cell selection/depletionhuman1ml, 5ml, 10mlAllhematopoietic clsDetails
GM-Tg-hg-T59001-iso-nanoIMBHuman CD16 Nano-mag BeadsDirectNon-releasableColumnFast isolation; high purity; ideal for automated workflowshuman1ml, 5ml, 10mlNK cellsDetails
GM-Tg-hg-T59001-iso-nanoIMB-CFHuman CD16 Column-Free Nano-mag BeadsDirectNon-releasableColumn-freeRapid processing; no column needed; perfect for quick experimentshuman1ml, 5ml, 10mlNK cellsDetails
GM-Tg-hg-T59001-iso-rel-kitReleasable Human CD16+ Cell Isolation KitIndirectReleasableColumnGentle bead removal for sensitive cells; superior recoveryhuman1ml, 5ml, 10mlNK cellsDetails
GM-Tg-hg-T59001-iso-rel-kit-CFReleasable Human CD16+ Cell Isolation Column-Free KitIndirectReleasableColumn-freeFlexible antibody combinations with fast bead removalhuman1ml, 5ml, 10mlNK cellsDetails
GM-Tg-hg-T59001-iso-kitIndirect Human CD16+ Cell Isolation KitIndirectNon-releasableColumnPermanent binding; high-purity isolation for industrial applicationshuman1ml, 5ml, 10mlNK cellsDetails
GM-Tg-hg-T59001-iso-kit-CFIndirect Human CD16+ Cell Isolation Column-Free KitIndirectNon-releasableColumn-freeCost-effective solution for standard cell selection/depletionhuman1ml, 5ml, 10mlNK cellsDetails

CDEx Flow Cytometry Antibodies

Fluorescent-Conjugated Antibodies (PE/APC/FITC/Biotin). These antibodies are conjugated to fluorescent dyes, such as Phycoerythrin (PE), Allophycocyanin (APC), or Fluorescein Isothiocyanate (FITC), making them particularly valuable for flow cytometry and multi-parameter analysis. Fluorescent labeling allows researchers to investigate specific cell populations by enabling the detection of markers on individual cells at a high sensitivity. Each dye has unique excitation and emission spectra, enabling multiplexing in a single experiment for a detailed and comprehensive analysis.

Cat No Product Name Speices Conjugate Size Cell population Products Information
GM-Tg-hg-MP0250-Ab-3-PE/FITC/APC/Biotin Anti-Human CD66b monoclonal antibody(mAb)(PE/FITC/APC/Biotin) human PE/FITC/APC/Biotin 25T, 100T, 500T Granulocyte Details
GM-Tg-hg-T66426-Ab-3/4/7/8-PE/FITC/APC/Biotin Anti-Human CD34 monoclonal antibody(mAb)(PE/FITC/APC/Biotin) human PE/FITC/APC/Biotin 25T, 100T, 500T Hematopoietic Stem Cell Details
GM-Tg-hg-T86323-Ab-1-PE/FITC/APC/Biotin Anti-Human NCAM1 (CD56) monoclonal antibody(mAb)(PE/FITC/APC/Biotin) mouse PE/FITC/APC/Biotin 25T, 100T, 500T NK cell Details
GM-Tg-hg-T23212-Ab-1-PE/FITC/APC/Biotin Anti-Human CD14 monoclonal antibody(mAb)(PE/FITC/APC/Biotin) mouse PE/FITC/APC/Biotin 25T, 100T, 500T Monocyte/Macrophage Details
GM-Tg-hg-T56365-Ab-1-PE/FITC/APC/Biotin Anti-Human CD19 monoclonal antibody(mAb)(PE/FITC/APC/Biotin) mouse PE/FITC/APC/Biotin 25T, 100T, 500T Bcell Details
GM-Tg-hg-T87075-Ab-1-PE/FITC/APC/Biotin Anti-Human CD3E monoclonal antibody(mAb)(PE/FITC/APC/Biotin) mouse PE/FITC/APC/Biotin 25T, 100T, 500T Pan-T cell Details
GM-Tg-hg-T10191-Ab-1/2-PE/FITC/APC/Biotin Anti-Human CD4 monoclonal antibody(mAb)(PE/FITC/APC/Biotin) mouse PE/FITC/APC/Biotin 25T, 100T, 500T CD4-T Details
GM-Tg-hg-TA040-Ab-1-PE/FITC/APC/Biotin Anti-Human CD8 monoclonal antibody(mAb)(PE/FITC/APC/Biotin) mouse PE/FITC/APC/Biotin 25T, 100T, 500T CD8-T Details
GM-Tg-hg-MP2610-Ab-3-PE/FITC/APC/Biotin Anti-Human TCR alpha-beta (abT) monoclonal antibody(mAb)(PE/FITC/APC/Biotin) human PE/FITC/APC/Biotin 25T, 100T, 500T Alpha-Beta T Cell Details
GM-Tg-hg-T13017-Ab-1-PE/FITC/APC/Biotin Anti-Human CD138 monoclonal antibody(mAb)(PE/FITC/APC/Biotin) mouse PE/FITC/APC/Biotin 25T, 100T, 500T Plasma Cell Details
GM-Tg-hg-T43115-8-Ab-4-PE/FITC/APC/Biotin Anti-Human CD45RA monoclonal antibody(mAb)(PE/FITC/APC/Biotin) human PE/FITC/APC/Biotin 25T, 100T, 500T Allhematopoietic cls Details
GM-Tg-hg-T43115-Ab-4-PE/FITC/APC/Biotin Anti-Human CD45 monoclonal antibody(mAb)(PE/FITC/APC/Biotin) human PE/FITC/APC/Biotin 25T, 100T, 500T Allhematopoietic cls Details
GM-Tg-hg-T59001-Ab-3-PE/FITC/APC/Biotin Anti-Human CD16 monoclonal antibody(mAb)(PE/FITC/APC/Biotin) human PE/FITC/APC/Biotin 25T, 100T, 500T NK cells Details

TAGEx CAR-Analytical Tools

The GeneMedi still aims to supply the superior CAR-T cell preparation service together with a plethora of valuable CAR detection kits, which are fundamental for accurate enumeration and comprehensive investigation of CAR-T cell therapies. The assortment presented would provide both researchers and clinicians with a full spectrum of reagents and antibodies necessary to characterize CAR-T cells at each step of the process.

For the proper detection of These CAR-T cell treatments, the GeneMedi portfolio features antibodies specific to different parts of the CAR construct; scFv, hinge, transmembrane and the intracellular signal domains. It is also presupposed that with the help of this range, possible changes in CAR expression, assembly, and function can be studied comprehensively to understand how the CAR-T cells behave after infusion and engage tumor cells.

To directly detect CAR expression, the antibodies employed in this method are designed to specifically bind novel epitopes that are part of the scFv of the CAR, allowing assessment of CAR-T cell numbers in patients' circulation. This is important for the overall assessment of CAR-T cells and their sustainability after the treatment, which gives an indication of the success of the particular therapy type.

Cat No Products name Products description Detail
GMLS-Tag003-Ab01 Anti-G4S Linker monoclonal antibody This antibody is expertly crafted to detect the G4S linker within CAR constructs, providing a reliable tool for monitoring CAR expression and ensuring the efficacy of CAR-T cell therapies. Details 
GTU-ADA-FMC63-Ab01~06 Anti-FMC63 monoclonal antibody Specifically targeting the FMC63 scFv used in CD19 CAR constructs, this antibody plays a crucial role in assessing the specificity and functionality of CD19-directed CAR-T cells, highlighting our focus on delivering precision in CAR-T cell therapy. Details 
GMLS-Tag002-Ab01 Anti-VHH monoclonal antibody Designed to recognize VHH domains, this antibody is a pivotal tool in the detection and analysis of CAR constructs that incorporate VHH domains. It offers a highly specific and sensitive means of verifying the presence and functionality of these innovative CAR constructs. Details 


Validation Data

  • ISOEx Immunocytes Cell Isolation Immunomagnetic Beads
  • CDEx Flow Cytometry Antibodies
  • TAGEx CAR-Analytical Tools

ISOEx Immunocytes Cell Isolation Immunomagnetic Beads

Efficient Isolation of Jurkat Cells Using GeneMedi's Indirect TCRα/β T Cell Isolation Kit

To evaluate the performance of GeneMedi's Indirect TCRα/β T Cell Isolation Kit, Jurkat cells were mixed with 293T-GFP cells at a 1:2 ratio, followed by magnetic separation using both GeneMedi's kit and a competitor's (Company M's TCRα/β T Cell Isolation Kit). The purity of isolated Jurkat cells was assessed via flow cytometry analysis. GeneMedi's Indirect TCRα/β T Cell Isolation Kit delivers superior cell isolation performance.

Figure 1. Efficient Isolation of Jurkat Cells Using GeneMedi's Indirect TCRα/β T Cell Isolation Kit.
The flow cytometry analysis of the purified Jurkat cells by using Company M's TCRα/β T Cell isolation kit and GeneMedi's indirect TCRα/β T Cell isolation kit.

ISOEx Immunocytes Cell Isolation Immunomagnetic Beads validation
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Figure 2. High-Purity Isolation of TCRα/β+ T Cells from Human PBMCs Using GeneMedi's Indirect TCRα/β T Cell Isolation Kit

ISOEx Immunocytes Cell Isolation Immunomagnetic Beads validation
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Figure 3. High-Purity Isolation of CD14+Cells from Human PBMCs Using GeneMedi's Indirect CD14+ Cell Isolation Kit

ISOEx Immunocytes Cell Isolation Immunomagnetic Beads validation
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Human peripheral blood mononuclear cells (PBMCs) were freshly recovered and subjected to TCRα/β+ T or CD14+ cell isolation using GeneMedi's Indirect Cell Isolation Kit and Company M's Cell kit. The isolated cell population was analyzed by flow cytometry to evaluate purity and efficiency. GeneMedi's Indirect TCRα/β T and CD14+ Cell Isolation Kits provide superior performance in isolating from human PBMCs, delivering high purity and yield for downstream applications.

SOLIDEX™-CDEx Flow Cytometry antibodies

GeneMedi's Flow Cytometry antibodies are validated to detect PBMC-derived specific cell types by flow cytometry.

GeneMedi's antibodies—Anti-Human CD3E, Anti-Human CD4, Anti-Human CD8, Anti-Human CD14, Anti-Human CD19, and Anti-Human NCAM1 (CD56)—are extensively validated for the detection of specific cell types derived from Peripheral Blood Mononuclear Cells (PBMCs) by flow cytometry. These antibodies enable accurate identification and profiling of immune cell subsets within PBMC populations, supporting diverse immunological studies and applications. These antibodies perform reliably in identifying critical immune cell subsets, including T cells, B cells, monocytes, and natural killer (NK) cells, providing essential tools for immunological and therapeutic research.

Comparative studies indicate that GeneMedi's antibody products offer performance on par with Company B's commercial antibodies. This similarity in performance means that researchers can expect comparable levels of sensitivity, specificity, and consistency when using GeneMedi's antibodies. Such equivalency provides researchers with confidence in using GeneMedi's products as effective alternatives, whether for immune profiling, cell population analysis, or functional assays.

Figure 1. GeneMedi's Anti-Human CD3E antibody, Anti-Human CD4 antibody, Anti-Human CD8 antibody, Anti-Human CD14 antibody, Anti-Human CD19 antibody, Anti-Human CD56 antibody, Anti-Human CD45 monoclonal antibody, Anti-Human CD66b monoclonal antibody and Anti-Human CD34 monoclonal antibody are validated to detect PBMC-derived specific cell types byflow cytometry.
A-F. Anti-Human CD3E antibody (A), Anti-Human CD4 antibody (B), Anti-Human CD8 antibody (C), Anti-Human CD14 antibody (D), Anti-Human CD19 antibody (E), Anti-Human NCAM1 (CD56) antibody (F). G. The Cat number and product name correspond to the antibodies used in this study.

cdex antibodies validation
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cdex-antibodies validation
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FMC64 and G4S Linker antibody validation

Figure 2. The GTU-ADA-FMC63-Ab01 and GMLS-Tag003-Ab-1 are validated to detect CAR-NK cells.

FMC64 antibody validation

Figure 3. The GTU-ADA-FMC63-Ab01 is validated to detect Simulate samples of CAR-NK infusion in patients.

G4S Linker antibody validation

Figure 4. For detecting CAR-T cells, GeneMedi's GMLS-Tag003-Ab-1 detection background is lower, and the detection results are closer to specific antigen detection, compared to Company C.

GMLS-Tag002-Ab01 effectively detects VHH-based format ant-Target CAR expression with great consistency with the target protein


Target protein (antigen) is usually used to detect anti-target CAR expression. For example, CD19 recombinant protein is used as a detection antigen for CAR position rate detection. However, the target protein is unique, expensive, and hard to produce. GeneMedi's anti-VHH antibody is a universal strategy for the detection of VHH-based format anti-Target CAR expression.

293T cells were transfected with CAR plasmids expressing VHH antibodies specific to target1, target2, target3, and target4. Following transfection, the expression of the corresponding CARs was confirmed using the specific recombinant proteins, GMLS-Tag002-Ab01, and a commercial Anti-VHH antibody (Company G).

The recombinant proteins were used as positive controls to benchmark CAR-positive detection. Statistical Analysis uses the positive detection ratio of GMLS-Tag002-Ab01 or Anti-VHH antibody (Company G) relative to the antigen-based detection. GMLS-Tag002-Ab01 achieves a consistency ratio close to 1.0. The data shows that the positive detection rate with GMLS-Tag002-Ab01 was comparable to that of the antigens, demonstrating nearly identical performance to the positive control. In contrast, the anti-VHH antibody (Company G) exhibited higher or lower detection sensitivity. The results indicate that GMLS-Tag002-Ab01 effectively detects the expressed VHH antibodies (nanobody, VHH-based bispecific antibody) on CAR-transfected 293T cells with high accuracy, comparable to the recombinant proteins. This establishes GMLS-Tag002-Ab01 as a reliable tool for detecting CAR expression in similar experiments.

VHH ELISA Validation
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Figure 5. GMLS-Tag002-Ab01 effectively evaluates the expression of anti-Target nanobody (VHH) on CAR-transfected 293T cells with higher specificity in flow cytometry.

A. The scatter plot shows the fluorescence intensity of CAR-expressing 293T cells stained with GMLS-Tag002-Ab01, Anti-VHH antibody (Company G), and the specific recombinant target protein (positive control).

B. GeneMedi's anti-VHH antibody shows great consistency with the antigen-based evaluation strategy in VHH-based format CAR expressing cell QC. Statistical Analysis uses the positive detection ratio of GMLS-Tag002-Ab01 or Anti-VHH antibody from Company G relative to the target protein-based detection.




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