GeneMedi SOLIDEX™ Immune Cell Solution

GeneMedi offers a comprehensive one-stop solution covering cell separation, flow cytometry analysis, and CAR-T cell therapy development, empowering precision medicine research and clinical translation.



About GeneMedi SOLIDEX™

SOLIDEX™ is GeneMedi's proprietary comprehensive solution for immune cell solution, dedicated to providing efficient and reliable tools for cell separation and analysis. This series includes the SOLIDEX™-ISOEx nanoscale non-destructive cell separation product matrix, SOLIDEX™-CDEx multi-color hypersensitive flow cytometry antibodies, and SOLIDEX™-TAGEx CAR multimodal analysis tools.

SOLIDEX™ Immune Cell Solution Detail

ISOEx Cell Isolation Nanobeads

Function: High-purity enrichment of specific immune cells or stem cells for downstream experiments.

Product Highlights:

  • Optimized antibodies targeting CD3, CD4, CD8, CD14, CD19, CD34, NK (CD56), monocytes (CD14), and more.

Core Technologies:

Category Type Description Advantages Disadvantages
Labeling Method Direct cell isolation Antibodies directly conjugated to magnetic beads Fastest method (single-step)
High specificity
Simple protocol
Limited flexibility
High capacity to antibodies
Indirect cell isolation Uses biotinylated secondary capture (reusable beads) Antibody flexibility
Cost-effective
Signal amplification possible
Longer protocol
Potential for higher background
Additional step required
Bead Type Releasable Allow competitive elution Better for sensitive applications
Simple workflow
More expensive beads
May interfere with some tasks
Non-releasable Form irreversible bonds (Streptavidin beads) Ideal for negative selection
More economical
Permanent bead attachment
Format Column-based Uses magnetic columns with 50nm beads Highest purity Requires columns
Slower processing
Higher cost
Column-free Uses larger beads with external magnets Fast processing (<15 min)
No column costs
Slightly lower purity
Less suitable for automation

Detail

CDEx Flow Cytometry Antibodies

Function: Multiplexed, high-sensitivity analysis of immune cell phenotypes at the single-cell level.

Product Portfolio:

  • PE/APC/FITC-Conjugated Antibodies: Targeting CD3E, CD4, CD8, CD14, CD19, NCAM1 (CD56), TCR αβ, and others.

  • Naked Antibodies: Support custom labeling (e.g., biotin, fluorescent dyes).

Technical Advantages:

  • Exceptional sensitivity and specificity for complex samples like PBMCs.

Detail

TAGEx CAR-Analytical Tools

Companion Detection Tools:

  • CAR-Specific Antibodies: Targeting scFv (e.g., FMC63), VHH, G4S nanobodies, hinge/transmembrane domains, and intracellular signaling motifs.

  • Quality Control: Simulated sample testing and reduced background signals (outperforms Company C).

Lentiviral Vector Services:

  • Target Proteins: CD19 (leukemia), BCMA (multiple myeloma), Her2 (breast cancer), GPC3 (hepatocellular carcinoma), etc.

  • Key Features: High transduction efficiency, low genotoxicity, and support for multi-gene payloads (≤6.5 kb).

Service Workflow:

  • Lentivirus packaging → CAR-T cell engineering → Functional validation → Preclinical/clinical trial support

Detail
Alzheimer's Disease (AD)

End-to-End Coverage

From cell isolation → phenotypic analysis → gene modification → functional validation.

Parkinson's Disease (PD)

Customization

Tailored solutions for antibody labeling, vector design, and target optimization.

Huntington's Disease (HD)

Synergy

Immunomagnetic bead-based purification enhances flow cytometry accuracy; lentiviral systems ensure efficient CAR-T production.

Huntington's Disease (HD)

Applications

Oncology immunotherapy, Autoimmune disease research, Rare disease modeling, CAR-T clinical pipeline development





SOLIDEX™ solution - Product list

  • ISOEx Cell Isolation Kit & Nanobeads
  • CDEx Flow Cytometry antibodies
  • TAGEx CAR-Analytical Tools

Our magnetic bead-based cell isolation portfolio now offers six tailored configurations, combining three critical parameters to match diverse experimental needs: Labeling Type (Direct/Indirect) x Bead Type (Non-releasable/Releasable) x Format (Column/Column-free)

  • CD66b+ Cell
  • CD34+ Cell
  • NK Cell
  • CD14+ Cell
  • B Cell
  • Pan-T Cell
  • CD4-T Cell
  • CD8-T Cell
  • TCR alpha-beta (abT)+ Cell
  • CD138+ Cell
  • CD45RA+ Cell
  • CD45+ Cell
  • CD16+ Cell
  • CD25+ Cell
Cell type Isolation method Cat.No Product Name Products Link
SOLIDEX™-ISOEx CD66b+ Cell Isolation Solution Positive CD66b+ Cell Selection GM-Tg-hg-T86323-iso-nanoIMB SOLIDEX™-ISOEx Human CD66b Nano-mag Beads (Column-Based) Details
GM-Tg-hg-MP0250-iso-nanoIMB-CF SOLIDEX™-ISOEx Human CD66b Nano-mag Beads (Column-Free) Details
GM-Tg-hg-MP0250-iso-rel-kit SOLIDEX™-ISOEx Indirect Releasable Human CD66b+ Cell Isolation Kit (Column-Based) Details
GM-Tg-hg-MP0250-iso-rel-kit-CF SOLIDEX™-ISOEx Indirect Releasable Human CD66b+ Cell Isolation Kit (Column-Free) Details
GM-Tg-hg-MP0250-iso-kit SOLIDEX™-ISOEx Indirect Human CD66b+ Cell Isolation Kit (Column-Based) Details
GM-Tg-hg-MP0250-iso-kit-CF SOLIDEX™-ISOEx Indirect Human CD66b+ Cell Isolation Kit (Column-Free) Details
CD66b+ Cell Depletion GM-Tg-hg-MP0250-dep-nanoIMB SOLIDEX™-ISOEx Human CD66b+ Cell Depletion Nano-mag Beads (Column-Based) Details
GM-Tg-hg-MP0250-dep-kit SOLIDEX™-ISOEx Indirect Human CD66b+ Cell Depletion Kit (Column-Based) Details
Cell type Isolation method Cat.No Product Name Products Link
SOLIDEX™ CD34+ Cell Isolation Solution Positive CD34+ Cell Selection GM-Tg-hg-T66426-iso-nanoIMB SOLIDEX™ Human CD34 Isolation Nanobeads (Column-based) Details
GM-Tg-hg-T66426-iso-nanoIMB-CF SOLIDEX™ Human CD34 Isolation Nanobeads (Column-free) Details
GM-Tg-hg-T66426-iso-rel-kit SOLIDEX™ Indirect Releasable Human CD34+ Cell Isolation Kit (Column-based) Details
GM-Tg-hg-T66426-iso-rel-kit-CF SOLIDEX™ Indirect Releasable Human CD34+ Cell Isolation Kit (Column-free) Details
GM-Tg-hg-T66426-iso-kit SOLIDEX™ Indirect Human CD34+ Cell Isolation Kit (Column-based) Details
GM-Tg-hg-T66426-iso-kit-CF SOLIDEX™ Indirect Human CD34+ Cell Isolation Kit (Column-free) Details
CD34+ Cell Depletion GM-Tg-hg-T66426-dep-nanoIMB SOLIDEX™ Human CD34+ Cell Depletion Nanobeads (Column-based) Details
GM-Tg-hg-T66426-dep-kit SOLIDEX™ Indirect Human CD34+ Cell Depletion Kit (Column-based) Details
Cell type Isolation method Cat.No Product Name Products Link
SOLIDEX™ NK Cell Isolation Solution Positive NK Cell Selection GM-Tg-hg-T86323-iso-nanoIMB SOLIDEX™ Human NCAM1 (CD56)+ NK Cell Isolation Nanobeads (Column-based) Details
GM-Tg-hg-T86323-iso-nanoIMB-CF SOLIDEX™ Human NCAM1 (CD56)+ NK Cell Isolation Nanobeads (Column-free) Details
GM-Tg-hg-T86323-iso-rel-kit Indirect Releasable Human NCAM1 (CD56)+ NK Cell Isolation Kit (Column-based) Details
GM-Tg-hg-T86323-iso-rel-kit-CF Indirect Releasable Human NCAM1 (CD56)+ NK Cell Isolation Kit (Column-free) Details
GM-Tg-hg-T86323-iso-kit SOLIDEX™ Indirect Human NCAM1 (CD56)+ NK Cell Isolation Kit (Column-based) Details
GM-Tg-hg-T86323-iso-kit-CF SOLIDEX™ Indirect Human NCAM1 (CD56)+ NK Cell Isolation Kit (Column-free) Details
Negative NK Cell Isolation (Untouched) GM-NK-Cell-iso-kit SOLIDEX™ Untouched Human NK Cell Isolation Kit (Column-based) Details
GM-NK-Cell-iso-kit-CF SOLIDEX™ Untouched Human NK Cell Isolation Kit (Column-free) Details
NK Cell Depletion GM-Tg-hg-T86323-dep-nanoIMB SOLIDEX™ Human NCAM1 (CD56)+ NK Cell Depletion Nanobeads (Column-based) Details
GM-Tg-hg-T86323-dep-kit SOLIDEX™ Indirect Human NCAM1 (CD56)+ NK Cell Depletion Kit (Column-based) Details
Cell type Isolation method Cat.No Product Name Products Link
SOLIDEX™ CD14+ Cell Isolation Solution Positive CD14+ Cell Selection GM-Tg-hg-T23212-iso-nanoIMB SOLIDEX™ Human CD14 Isolation Nanobeads (Column-based) Details
GM-Tg-hg-T23212-iso-nanoIMB-CF SOLIDEX™ Human CD14 Isolation Nanobeads (Column-free) Details
GM-Tg-hg-T23212-iso-rel-kit SOLIDEX™ Indirect Releasable Human CD14+ Cell Isolation Kit (Column-based) Details
GM-Tg-hg-T23212-iso-rel-kit-CF SOLIDEX™ Indirect Releasable Human CD14+ Cell Isolation Kit (Column-free) Details
GM-Tg-hg-T23212-iso-kit SOLIDEX™ Indirect Human CD14+ Cell Isolation Kit (Column) Details
GM-Tg-hg-T23212-iso-kit-CF SOLIDEX™ Indirect Human CD14+ Cell Isolation Kit (Column-free) Details
CD14+ Cell Depletion GM-Tg-hg-T23212-dep-nanoIMB SOLIDEX™ Human CD14+ Cell Depletion Nanobeads (Column-based) Details
GM-Tg-hg-T23212-dep-kit SOLIDEX™ Indirect Human CD14+ Cell Depletion Kit (Column-based) Details
Cell type Isolation method Cat.No Product Name Products Link
SOLIDEX™ B Cell Isolation Solution Positive B Cell Selection GM-Tg-hg-T56365-iso-nanoIMB SOLIDEX™ Human CD19 Isolation Nanobeads (Column-based) Details
GM-Tg-hg-T56365-iso-nanoIMB-CF SOLIDEX™ Human CD19 Isolation Nanobeads (Column-free) Details
GM-Tg-hg-T56365-iso-rel-kit SOLIDEX™ Indirect Releasable Human CD19+ B Cell Isolation Kit (Column-based) Details
GM-Tg-hg-T56365-iso-rel-kit-CF SOLIDEX™ Indirect Releasable Human CD19+ B Cell Isolation Kit (Column-free) Details
GM-Tg-hg-T56365-iso-kit SOLIDEX™ Indirect Human CD19+ B Cell Isolation Kit (Column) Details
GM-Tg-hg-T56365-iso-kit-CF SOLIDEX™ Indirect Human CD19+ B Cell Isolation Kit (Column-free) Details
Negative B Cell Isolation (Untouched) GM-B-Cell-iso-kit SOLIDEX™ Untouched Human B Cell Isolation Kit (Column-based) Details
GM-B-Cell-iso-kit-CF SOLIDEX™ Untouched Human B Cell Isolation Kit (Column-free) Details
B Cell Depletion GM-Tg-hg-T56365-dep-nanoIMB SOLIDEX™ Human CD19+ B Cell Depletion Nanobeads (Column-based) Details
GM-Tg-hg-T56365-dep-kit SOLIDEX™ Indirect Human CD19+ B Cell Depletion Kit (Column-based) Details
Cell type Isolation method Cat.No Product Name Products Link
SOLIDEX™ Pan-T Cell Isolation Solution Positive Pan-T Cell Selection GM-Tg-hg-T87075-iso-nanoIMB SOLIDEX™ Human CD3 Isolation Nanobeads (Column-based) Details
GM-Tg-hg-T87075-iso-nanoIMB-CF SOLIDEX™ Human CD3 Isolation Nanobeads (Column-free) Details
GM-Tg-hg-T87075-iso-rel-kit SOLIDEX™ Indirect Releasable Human CD3+ Pan-T Cell Isolation Kit (Column-based) Details
GM-Tg-hg-T87075-iso-rel-kit-CF SOLIDEX™ Indirect Releasable Human CD3+ Pan-T Cell Isolation Kit (Column-free) Details
GM-Tg-hg-T87075-iso-kit SOLIDEX™ Indirect Human CD3+ Pan-T Cell Isolation Kit (Column-based) Details
GM-Tg-hg-T87075-iso-kit-CF SOLIDEX™ Indirect Human CD3+ Pan-T Cell Isolation Kit (Column-free) Details
Negative Pan-T Cell Isolation (Untouched) GM-Pan-T-Cell-iso-kit SOLIDEX™ Untouched Human Pan-T Cell Isolation Kit (Column-based) Details
GM-Pan-T-Cell-iso-kit-CF SOLIDEX™ Untouched Human Pan-T Cell Isolation Kit (Column-free) Details
Pan-T Cell Depletion GM-Tg-hg-T87075-dep-nanoIMB SOLIDEX™ Human CD3+ Pan-T Cell Depletion Nanobeads (Column-based) Details
GM-Tg-hg-T87075-dep-kit SOLIDEX™ Indirect Human CD3+ Pan-T Cell Depletion Kit (Column-based) Details
Cell type Isolation method Cat.No Product Name Products Link
SOLIDEX™ CD4+ T Cell Isolation Solution Positive CD4+ T Cell Selection GM-Tg-hg-T10191-iso-nanoIMB SOLIDEX™ Human CD4 Isolation Nanobeads (Column-based) Details
GM-Tg-hg-T10191-iso-nanoIMB-CF SOLIDEX™ Human CD4 Isolation Nanobeads (Column-free) Details
GM-Tg-hg-T10191-iso-rel-kit SOLIDEX™ Indirect Releasable Human CD4+ T Cell Isolation Kit (Column-based) Details
GM-Tg-hg-T10191-iso-rel-kit-CF SOLIDEX™ Indirect Releasable Human CD4+ T Cell Isolation Kit (Column-free) Details
GM-Tg-hg-T10191-iso-kit SOLIDEX™ Indirect Human CD4+ T Cell Isolation Kit (Column-based) Details
GM-Tg-hg-T10191-iso-kit-CF SOLIDEX™ Indirect Human CD4+ T Cell Isolation Kit (Column-free) Details
Negative CD4+ T Cell Isolation (Untouched) GM-CD4-T-Cell-iso-kit SOLIDEX™ Untouched Human CD4+ T Cell Isolation Kit (Column-based) Details
GM-CD4-T-Cell-iso-kit-CF SOLIDEX™ Untouched Human CD4+ T Cell Isolation Kit (Column-free) Details
CD4+ T Cell Depletion GM-Tg-hg-T10191-dep-nanoIMB SOLIDEX™ Human CD4+ T Cell Depletion Nanobeads (Column-based) Details
GM-Tg-hg-T10191-dep-kit SOLIDEX™ Indirect Human CD4+ T Cell Depletion Kit (Column-based) Details
Cell type Isolation method Cat.No Product Name Products Link
SOLIDEX™ CD8+ T Cell Isolation Solution Positive CD8+ T Cell Selection GM-Tg-hg-TA040-iso-nanoIMB SOLIDEX™ Human CD8 Isolation Nanobeads (Column-based) Details
GM-Tg-hg-TA040-iso-nanoIMB-CF SOLIDEX™ Human CD8 Isolation Nanobeads (Column-free) Details
GM-Tg-hg-TA040-iso-rel-kit SOLIDEX™ Indirect Releasable Human CD8+ T Cell Isolation Kit (Column-based) Details
GM-Tg-hg-TA040-iso-rel-kit-CF SOLIDEX™ Indirect Releasable Human CD8+ T Cell Isolation Kit (Column-free) Details
GM-Tg-hg-TA040-iso-kit SOLIDEX™ Indirect Human CD8+ T Cell Isolation Kit (Column-based) Details
GM-Tg-hg-TA040-iso-kit-CF SOLIDEX™ Indirect Human CD8+ T Cell Isolation Kit (Column-free) Details
Negative CD8+ T Cell Isolation (Untouched) GM-CD8-T-Cell-iso-kit SOLIDEX™ Untouched Human CD8+ T Cell Isolation Kit (Column-based) Details
GM-CD8-T-Cell-iso-kit-CF SOLIDEX™ Untouched Human CD8+ T Cell Isolation Kit (Column-free) Details
CD8+ T Cell Depletion GM-Tg-hg-TA040-dep-nanoIMB SOLIDEX™ Human CD8+ T Cell Depletion Nanobeads (Column-based) Details
GM-Tg-hg-TA040-dep-kit SOLIDEX™ Indirect Human CD8+ T Cell Depletion Kit (Column-based) Details
Cell type Isolation method Cat.No Product Name Products Link
SOLIDEX™ TCR alpha-beta (abT)+ Cell Isolation Solution Positive TCR alpha-beta (abT) + Cell Selection GM-Tg-hg-MP2610-iso-nanoIMB SOLIDEX™ Human TCR alpha-beta (abT) Isolation Nanobeads (Column-based) Details
GM-Tg-hg-MP2610-iso-nanoIMB-CF SOLIDEX™ Human TCR alpha-beta (abT) Isolation Nanobeads (Column-free) Details
GM-Tg-hg-MP2610-iso-rel-kit SOLIDEX™ Indirect Releasable Human TCR alpha-beta (abT)+ Cell Isolation Kit (Column-based) Details
GM-Tg-hg-MP2610-iso-rel-kit-CF SOLIDEX™ Indirect Releasable Human TCR alpha-beta (abT)+ Cell Isolation Kit (Column-free) Details
GM-Tg-hg-MP2610-iso-kit SOLIDEX™ Indirect Human TCR alpha-beta (abT)+ Cell Isolation Kit (Column-based) Details
GM-Tg-hg-MP2610-iso-kit-CF SOLIDEX™ Indirect Human TCR alpha-beta (abT)+ Cell Isolation Kit (Column-free) Details
TCR alpha-beta (abT) + Cell Depletion GM-Tg-hg-MP2610-dep-nanoIMB SOLIDEX™ Human TCR alpha-beta (abT)+ Cell Depletion Nanobeads (Column-based) Details
GM-Tg-hg-MP2610-dep-kit SOLIDEX™ Indirect Human TCR alpha-beta (abT)+ Cell Depletion Kit (Column-based) Details
Cell type Isolation method Cat.No Product Name Products Link
SOLIDEX™ CD138+ Cell Isolation Solution Positive CD138+ Cell Selection GM-Tg-hg-T13017-iso-nanoIMB SOLIDEX™ Human CD138 Isolation Nanobeads (Column-based) Details
GM-Tg-hg-T13017-iso-nanoIMB-CF SOLIDEX™ Human CD138 Isolation Nanobeads (Column-free) Details
GM-Tg-hg-T13017-iso-rel-kit SOLIDEX™ Indirect Releasable Human CD138+ Cell Isolation Kit (Column-based) Details
GM-Tg-hg-T13017-iso-rel-kit-CF SOLIDEX™ Indirect Releasable Human CD138+ Cell Isolation Kit (Column-free) Details
GM-Tg-hg-T13017-iso-kit SOLIDEX™ Indirect Human CD138+ Cell Isolation Kit (Column-based) Details
GM-Tg-hg-T13017-iso-kit-CF SOLIDEX™ Indirect Human CD138+ Cell Isolation Kit (Column-free) Details
CD138+ Cell Depletion GM-Tg-hg-T13017-dep-nanoIMB SOLIDEX™ Human CD138+ Cell Depletion Nanobeads (Column-based) Details
GM-Tg-hg-T13017-dep-kit SOLIDEX™ Indirect Human CD138+ Cell Depletion Kit (Column-based) Details
Cell type Isolation method Cat.No Product Name Products Link
SOLIDEX™ CD45RA+ Cell Isolation Solution Positive CD45RA+ Cell Selection GM-Tg-hg-T43115-8-iso-nanoIMB SOLIDEX™ Human CD45RA Isolation Nanobeads (Column-based) Details
GM-Tg-hg-T43115-8-iso-nanoIMB-CF SOLIDEX™ Human CD45RA Isolation Nanobeads (Column-free) Details
GM-Tg-hg-T43115-8-iso-rel-kit SOLIDEX™ Indirect Releasable Human CD45RA+ Cell Isolation Kit (Column-based) Details
GM-Tg-hg-T43115-8-iso-rel-kit-CF SOLIDEX™ Indirect Releasable Human CD45RA+ Cell Isolation Kit (Column-free) Details
GM-Tg-hg-T43115-8-iso-kit SOLIDEX™ Indirect Human CD45RA+ Cell Isolation Kit (Column-based) Details
GM-Tg-hg-T43115-8-iso-kit-CF SOLIDEX™ Indirect Human CD45RA+ Cell Isolation Kit (Column-free) Details
CD45RA+ Cell Depletion GM-Tg-hg-T43115-8-dep-nanoIMB SOLIDEX™ Human CD45RA+ Cell Depletion Nanobeads (Column-based) Details
GM-Tg-hg-T43115-8-dep-kit SOLIDEX™ Indirect Human CD45RA+ Cell Depletion Kit (Column-based) Details
Cell type Isolation method Cat.No Product Name Products Link
SOLIDEX™ CD45+ Cell Isolation Solution Positive CD45+ Cell Selection GM-Tg-hg-T43115-iso-nanoIMB SOLIDEX™ Human CD45 Isolation Nanobeads (Column-based) Details
GM-Tg-hg-T43115-iso-nanoIMB-CF SOLIDEX™ Human CD45 Isolation Nanobeads (Column-free) Details
GM-Tg-hg-T43115-iso-rel-kit SOLIDEX™ Indirect Releasable Human CD45+ Cell Isolation Kit (Column-based) Details
GM-Tg-hg-T43115-iso-rel-kit-CF SOLIDEX™ Indirect Releasable Human CD45+ Cell Isolation Kit (Column-free) Details
GM-Tg-hg-T43115-iso-kit SOLIDEX™ Indirect Human CD45+ Cell Isolation Kit (Column-based) Details
GM-Tg-hg-T43115-iso-kit-CF SOLIDEX™ Indirect Human CD45+ Cell Isolation Kit (Column-free) Details
CD45+ Cell Depletion GM-Tg-hg-T43115-dep-nanoIMB SOLIDEX™ Human CD45+ Cell Depletion Nanobeads (Column-based) Details
GM-Tg-hg-T43115-dep-kit SOLIDEX™ Indirect Human CD45+ Cell Depletion Kit (Column-based) Details
Cell type Isolation method Cat.No Product Name Products Link
SOLIDEX™ CD16+ Cell Isolation Solution Positive CD16+ Cell Selection GM-Tg-hg-T59001-iso-nanoIMB SOLIDEX™ Human CD16 Isolation Nanobeads (Column-based) Details
GM-Tg-hg-T59001-iso-nanoIMB-CF SOLIDEX™ Human CD16 Isolation Nanobeads (Column-free) Details
GM-Tg-hg-T59001-iso-rel-kit SOLIDEX™ Indirect Releasable Human CD16+ Cell Isolation Kit (Column-based) Details
GM-Tg-hg-T59001-iso-rel-kit-CF SOLIDEX™ Indirect Releasable Human CD16+ Cell Isolation Kit (Column-free) Details
GM-Tg-hg-T59001-iso-kit SOLIDEX™ Indirect Human CD16+ Cell Isolation Kit (Column-based) Details
GM-Tg-hg-T59001-iso-kit-CF SOLIDEX™ Indirect Human CD16+ Cell Isolation Kit (Column-free) Details
CD16+ Cell Depletion GM-Tg-hg-T59001-dep-nanoIMB SOLIDEX™ Human CD16+ Cell Depletion Nanobeads (Column-based) Details
GM-Tg-hg-T59001-dep-kit SOLIDEX™ Indirect Human CD16+ Cell Depletion Kit (Column-based) Details
Cell type Isolation method Cat.No Product Name Products Link
SOLIDEX™ CD25+ Cell Isolation Solution Positive CD25+ Cell Selection GM-Tg-hg-T03313-iso-nanoIMB SOLIDEX™ Human CD25 Isolation Nanobeads (Column-based) Details
GM-Tg-hg-T03313-iso-nanoIMB-CF SOLIDEX™ Human CD25 Isolation Nanobeads (Column-free) Details
GM-Tg-hg-T03313-iso-rel-kit SOLIDEX™ Indirect Releasable Human CD25+ Cell Isolation Kit (Column-based) Details
GM-Tg-hg-T03313-iso-rel-kit-CF SOLIDEX™ Indirect Releasable Human CD25+ Cell Isolation Kit (Column-free) Details
GM-Tg-hg-T03313-iso-kit SOLIDEX™ Indirect Human CD25+ Cell Isolation Kit (Column-based) Details
GM-Tg-hg-T03313-iso-kit-CF SOLIDEX™ Indirect Human CD25+ Cell Isolation Kit (Column-free) Details
CD25+ Cell Depletion GM-Tg-hg-T03313-dep-nanoIMB SOLIDEX™ Human CD25+ Cell Depletion Nanobeads (Column-based) Details
GM-Tg-hg-T03313-dep-kit SOLIDEX™ Indirect Human CD25+ Cell Depletion Kit (Column-based) Details

CDEx Flow Cytometry Antibodies

Fluorescent-Conjugated Antibodies (PE/APC/FITC/Biotin). These antibodies are conjugated to fluorescent dyes, such as Phycoerythrin (PE), Allophycocyanin (APC), or Fluorescein Isothiocyanate (FITC), making them particularly valuable for flow cytometry and multi-parameter analysis. Fluorescent labeling allows researchers to investigate specific cell populations by enabling the detection of markers on individual cells at a high sensitivity. Each dye has unique excitation and emission spectra, enabling multiplexing in a single experiment for a detailed and comprehensive analysis.

Cat No Product Name Speices Conjugate Size Cell population Products Information
GM-Tg-hg-MP0250-Ab-3-PE/FITC/APC/Biotin Anti-Human CD66b monoclonal antibody(mAb)(PE/FITC/APC/Biotin) human PE/FITC/APC/Biotin 25T, 100T, 500T Granulocyte Details
GM-Tg-hg-T66426-Ab-3/4/7/8-PE/FITC/APC/Biotin Anti-Human CD34 monoclonal antibody(mAb)(PE/FITC/APC/Biotin) human PE/FITC/APC/Biotin 25T, 100T, 500T Hematopoietic Stem Cell Details
GM-Tg-hg-T86323-Ab-1-PE/FITC/APC/Biotin Anti-Human NCAM1 (CD56) monoclonal antibody(mAb)(PE/FITC/APC/Biotin) mouse PE/FITC/APC/Biotin 25T, 100T, 500T NK cell Details
GM-Tg-hg-T23212-Ab-1-PE/FITC/APC/Biotin Anti-Human CD14 monoclonal antibody(mAb)(PE/FITC/APC/Biotin) mouse PE/FITC/APC/Biotin 25T, 100T, 500T Monocyte/Macrophage Details
GM-Tg-hg-T56365-Ab-1-PE/FITC/APC/Biotin Anti-Human CD19 monoclonal antibody(mAb)(PE/FITC/APC/Biotin) mouse PE/FITC/APC/Biotin 25T, 100T, 500T Bcell Details
GM-Tg-hg-T87075-Ab-1-PE/FITC/APC/Biotin Anti-Human CD3E monoclonal antibody(mAb)(PE/FITC/APC/Biotin) mouse PE/FITC/APC/Biotin 25T, 100T, 500T Pan-T cell Details
GM-Tg-hg-T10191-Ab-1/2-PE/FITC/APC/Biotin Anti-Human CD4 monoclonal antibody(mAb)(PE/FITC/APC/Biotin) mouse PE/FITC/APC/Biotin 25T, 100T, 500T CD4-T Details
GM-Tg-hg-TA040-Ab-1-PE/FITC/APC/Biotin Anti-Human CD8 monoclonal antibody(mAb)(PE/FITC/APC/Biotin) mouse PE/FITC/APC/Biotin 25T, 100T, 500T CD8-T Details
GM-Tg-hg-MP2610-Ab-3-PE/FITC/APC/Biotin Anti-Human TCR alpha-beta (abT) monoclonal antibody(mAb)(PE/FITC/APC/Biotin) human PE/FITC/APC/Biotin 25T, 100T, 500T Alpha-Beta T Cell Details
GM-Tg-hg-T13017-Ab-1-PE/FITC/APC/Biotin Anti-Human CD138 monoclonal antibody(mAb)(PE/FITC/APC/Biotin) mouse PE/FITC/APC/Biotin 25T, 100T, 500T Plasma Cell Details
GM-Tg-hg-T43115-8-Ab-4-PE/FITC/APC/Biotin Anti-Human CD45RA monoclonal antibody(mAb)(PE/FITC/APC/Biotin) human PE/FITC/APC/Biotin 25T, 100T, 500T Allhematopoietic cls Details
GM-Tg-hg-T43115-Ab-4-PE/FITC/APC/Biotin Anti-Human CD45 monoclonal antibody(mAb)(PE/FITC/APC/Biotin) human PE/FITC/APC/Biotin 25T, 100T, 500T Allhematopoietic cls Details
GM-Tg-hg-T59001-Ab-3-PE/FITC/APC/Biotin Anti-Human CD16 monoclonal antibody(mAb)(PE/FITC/APC/Biotin) human PE/FITC/APC/Biotin 25T, 100T, 500T NK cells Details

TAGEx CAR-Analytical Tools

The GeneMedi still aims to supply the superior CAR-T cell preparation service together with a plethora of valuable CAR detection kits, which are fundamental for accurate enumeration and comprehensive investigation of CAR-T cell therapies. The assortment presented would provide both researchers and clinicians with a full spectrum of reagents and antibodies necessary to characterize CAR-T cells at each step of the process.

For the proper detection of These CAR-T cell treatments, the GeneMedi portfolio features antibodies specific to different parts of the CAR construct; scFv, hinge, transmembrane and the intracellular signal domains. It is also presupposed that with the help of this range, possible changes in CAR expression, assembly, and function can be studied comprehensively to understand how the CAR-T cells behave after infusion and engage tumor cells.

To directly detect CAR expression, the antibodies employed in this method are designed to specifically bind novel epitopes that are part of the scFv of the CAR, allowing assessment of CAR-T cell numbers in patients' circulation. This is important for the overall assessment of CAR-T cells and their sustainability after the treatment, which gives an indication of the success of the particular therapy type.

Cat No Products name Products description Detail
GMLS-Tag003-Ab01 Anti-G4S Linker monoclonal antibody This antibody is expertly crafted to detect the G4S linker within CAR constructs, providing a reliable tool for monitoring CAR expression and ensuring the efficacy of CAR-T cell therapies. Details 
GTU-ADA-FMC63-Ab01~06 Anti-FMC63 monoclonal antibody Specifically targeting the FMC63 scFv used in CD19 CAR constructs, this antibody plays a crucial role in assessing the specificity and functionality of CD19-directed CAR-T cells, highlighting our focus on delivering precision in CAR-T cell therapy. Details 
GMLS-Tag002-Ab01 Anti-VHH monoclonal antibody Designed to recognize VHH domains, this antibody is a pivotal tool in the detection and analysis of CAR constructs that incorporate VHH domains. It offers a highly specific and sensitive means of verifying the presence and functionality of these innovative CAR constructs. Details 


Validation Data

  • ISOEx Cell Isolation Kit & Nanobeads
  • CDEx Flow Cytometry Antibodies
  • TAGEx CAR-Analytical Tools

ISOEx Cell Isolation Kit & Nanobeads

GeneMedi's SOLIDEX™-ISOEx Nanobeads: uniform size and regular shape

The SOLIDEX™-ISOEx Nanobeads utilize superparamagnetic iron oxide particles with high uniformity and a particle size of 50 nm, offering rapid response to magnetic fields and no significant impact on cell viability or activity. Experimental results demonstrate that, compared to those from Company M, the SOLIDEX™-ISOEx Nanobeads have more consistent size and even more regular shape.

Figure 1. The SOLIDEX™-ISOEx Nanobeads from GeneMedi exhibit uniform size and regular shape.

ISOEx Cell Isolation Kit & Nanobeads validation
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Efficient Isolation of Jurkat Cells Using SOLIDEX™-ISOEx Indirect Human TCR alpha-beta (abT)+ Cell Isolation Kit (Column-Based)

Catalog No. GM-Tg-hg-MP2610-iso-kit
To evaluate the performance of GeneMedi’s SOLIDEX™-ISOEx Indirect Human TCR alpha-beta (abT)+ Cell Isolation Kit (Column-Based), Jurkat cells were mixed with 293T-GFP cells at a 1:2 ratio, followed by magnetic separation using both GeneMedi’s kit and a competitor’s (Company M’s TCRα/β T Cell Isolation Kit). The purity of isolated Jurkat cells was assessed via flow cytometry analysis. SOLIDEX™-ISOEx Indirect Human TCR alpha-beta (abT)+ Cell Isolation Kit (Column-Based) delivers superior cell isolation performance.

Figure 2. Efficient Isolation of Jurkat Cells Using SOLIDEX™-ISOEx Indirect Human TCR alpha-beta (abT)+ Cell Isolation Kit (Column-Based). The flow cytometry analysis of the purified Jurkat cells by using Company M’s TCRα/β T Cell isolation kit and SOLIDEX™-ISOEx Indirect Human TCR alpha-beta (abT)+ Cell Isolation Kit (Column-Based).

ISOEx Cell Isolation Kit & Nanobeads validation
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High-Purity Isolation of TCRα/β+ T Cells from Human PBMCs Using SOLIDEX™-ISOEx Indirect Human TCR alpha-beta (abT)+ Cell Isolation Kit (Column-Based).

Catalog No. GM-Tg-hg-MP2610-iso-kit
Human peripheral blood mononuclear cells (PBMCs) were freshly recovered and subjected to TCRα/β+ T cell isolation using GeneMedi’s Indirect TCRα/β T Cell Isolation Kit and Company M’s TCRα/β T Cell kit. The isolated cell population was analyzed by flow cytometry to evaluate purity and efficiency. SOLIDEX™-ISOEx Indirect Human TCR alpha-beta (abT)+ Cell Isolation Kit (Column-Based) provides superior performance in isolating TCRα/β+ T cells from human PBMCs, delivering high purity and yield for downstream applications.

Figure 3. High-Purity Isolation of TCRα/β+ T Cells from Human PBMCs Using SOLIDEX™-ISOEx Indirect Human TCR alpha-beta (abT)+ Cell Isolation Kit (Column-Based). The flow cytometry analysis of the isolated cells from cryopreserved PBMCs.

ISOEx Cell Isolation Kit & Nanobeads validation
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High-Purity Isolation of CD14+ Cells from Human PBMCs Using SOLIDEX™-ISOEx Indirect Human CD14+ Cell Depletion Kit (Column-Based).

Catalog No. GM-Tg-hg-T23212-dep-kit
Human peripheral blood mononuclear cells (PBMCs) were freshly recovered and subjected to CD14+ cell isolation using GeneMedi’s Indirect Human CD14+ Cell Depletion Kit (Column-Based) and Company M’s CD14+ Cell kit. The isolated cell population was analyzed by flow cytometry to evaluate purity and efficiency. SOLIDEX™-ISOEx Indirect Human CD14+ Cell Depletion Kit (Column-Based) provides superior performance in isolating CD14+ T cells from human PBMCs, delivering high purity and yield for downstream applications.

Figure 4. High-Purity Isolation of CD14+ Cells from Human PBMCs Using SOLIDEX™-ISOEx Indirect Human CD14+ Cell Depletion Kit (Column-Based). The flow cytometry analysis of the isolated cells from cryopreserved PBMCs.

ISOEx Cell Isolation Kit & Nanobeads validation
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Efficient Isolation of NK Cells Using SOLIDEX™-ISOEx Untouched Human NK Cell Isolation Kit (Column-Based)

Catalog No.GM-Tg-hg-NK-Cell-iso-kit
To determine the purity of isolated NK cells, CD56+ NK cells were magnetically sorted from human peripheral blood mononuclear cells (PBMCs). Cells before and after separation were stained with CD3-APC and CD56-PE antibodies and subsequently analyzed by flow cytometry. Results demonstrated a remarkable increase in CD56+ NK cell purity from 8.19% pre-isolated to 94.3% post-isolated, confirming highly effective NK cell enrichment.

Figure 5. Efficient Isolation of NK Cells Using SOLIDEX™-ISOEx Untouched Human NK Cell Isolation Kit (Column-Based). The non-NK cells were labeled with biotinylated antibodies. After incubating with anti-biotin magnetic nanobeads, these cells were depleted by cell isolation column. The NK cells were harvested by collecting the flowthrough component. The NK cells in pre-isolated human PBMCs. NK cells with high purity were enriched.

ISOEx Cell Isolation Kit & Nanobeads validation
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High-Purity Isolation of NK Cells from Human PBMCs Using SOLIDEX™-ISOEx Untouched Human NK Cell Isolation Kit (Column-Based)

Catalog No.GM-Tg-hg-NK-Cell-iso-kit
Human peripheral blood mononuclear cells (PBMCs) were freshly recovered and subjected to NK cell isolation using SOLIDEX™-ISOEx Untouched Human NK Cell Isolation Kit (Column-Based) and Company M’s NK Cell kit. The isolated cell population was analyzed by flow cytometry to evaluate purity and recovery rate. SOLIDEX™-ISOEx Untouched Human NK Cell Isolation Kit (Column-Based) provides superior performance in isolating NK cells from human PBMCs, delivering high purity and recovery rate for downstream applications.

Figure 6. High-Purity Isolation of NK Cells from Human PBMCs Using SOLIDEX™-ISOEx Untouched Human NK Cell Isolation Kit (Column-Based). The flow cytometry analysis of the isolated cells from cryopreserved PBMCs.

ISOEx Cell Isolation Kit & Nanobeads validation
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Efficient Isolation of Pan-T Cells Using SOLIDEX™-ISOEx Human CD3 Isolation Nanobeads (Column-Based)

Catalog No.GM-Tg-hg-T87075-iso-nanoIMB
To assess the purity of isolated T cells, CD3+ T cells were magnetically sorted from human peripheral blood mononuclear cells (PBMCs). Cells before and after separation were stained with APC-conjugated CD3 antibody and propidium iodide (PI), followed by flow cytometric analysis. The results demonstrated a significant increase in CD3+ T cell purity from 52.6% pre-isolated to 95.0% post-isolated, confirming successful T cell isolation.

Figure 7. Efficient Isolation of Pan-T Cells Using SOLIDEX™-ISOEx Human CD3 Isolation Nanobeads (Column-Based). The T cells were labeled with SOLIDEX™-ISOEx Nanobeads conjugated with anti-CD3 antibody. And then these cells were enriched by using cell isolation column. The T cells in pre-isolated human PBMCs. T cells with high purity and motility were enriched.

ISOEx Cell Isolation Kit & Nanobeads validation
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Efficient Isolation of Pan-T Cells Using SOLIDEX™-ISOEx Human CD3 Isolation Nanobeads (Column-Free)

Catalog No.GM-Tg-hg-T87075-iso-nanoIMB-CF
To evaluate the purity of isolated T cells, CD3+ T cells were magnetically sorted from human peripheral blood mononuclear cells (PBMCs). Cells before and after separation were stained with APC-conjugated CD3 antibody and analyzed by flow cytometry. The CD3+ T cell purity demonstrated a substantial increase from 65.9% pre-separation to 98.6% post-separation, confirming highly effective T cell isolation.

Figure 8. Efficient Isolation of Pan-T Cells Using SOLIDEX™-ISOEx Human CD3 Isolation Nanobeads (Column-Free). The T cells were labeled with SOLIDEX™-ISOEx Nanobeads conjugated with anti-CD3 antibody. And then these cells were enriched by using magnetic separator. The T cells in pre-isolated human PBMCs. T cells with high purity and motility were enriched.

ISOEx Cell Isolation Kit & Nanobeads validation
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Efficient Isolation of CD4+ T Cells Using SOLIDEX™-ISOEx Human CD4 Isolation Nanobeads (Column-Based)

Catalog No. GM-Tg-hg-T10191-iso-nanoIMB
To assess the purity of isolated CD4+ T cells, magnetic separation was performed on human peripheral blood mononuclear cells (PBMCs). Both pre- and post-isolation cells were labeled with CD3-APC and CD4-PE antibodies and subjected to flow cytometric analysis. The purity of CD4+ T cells was significantly enhanced, rising from 28.1% before isolation to 97.0% after isolation, indicating highly efficient enrichment of CD4+ T cells.

Figure 9. High-Efficiency Enrichment of CD4+ Cells with SOLIDEX™-ISOEx Human CD4 Isolation Nanobeads (Column-Based). Cells were incubated with anti-CD4 antibody-conjugated magnetic nanobeads and passed through an isolation column for positive selection. Flow cytometry shows CD4+ T cells in the input PBMC population and the resulting highly purified fraction.

ISOEx Cell Isolation Kit & Nanobeads validation
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Efficient Isolation of CD8+ T Cells Using SOLIDEX™-ISOEx Human CD8 Isolation Nanobeads (Column-Based)

Catalog No. GM-Tg-hg-TA040-iso-nanoIMB
To determine the purity of isolated CD8+ T cell, CD8+ T cells were magnetically sorted from human peripheral blood mononuclear cells (PBMCs). Cells before and after separation were stained with CD3-APC and CD8-PE antibodies and subsequently analyzed by flow cytometry. Results demonstrated a remarkable increase in CD8+ T cell purity from 16.6% pre-isolated to 94.6% post-isolated, confirming highly effective CD8+ T cell enrichment.

Figure 10. Efficient Isolation of CD8+ Cells Using SOLIDEX™-ISOEx Human CD8 Isolation Nanobeads (Column-Based). The T cells were labeled with magnetic nanobeads conjugated with anti-CD8 antibody. And then these cells were enriched by using cell isolation column. The T cells in pre-isolated human PBMCs . T cells with high purity were enriched.

ISOEx Cell Isolation Kit & Nanobeads validation
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SOLIDEX™-CDEx Flow Cytometry antibodies

GeneMedi's Flow Cytometry antibodies are validated to detect PBMC-derived specific cell types by flow cytometry.

GeneMedi's antibodies—Anti-Human CD3E, Anti-Human CD4, Anti-Human CD8, Anti-Human CD14, Anti-Human CD19, and Anti-Human NCAM1 (CD56)—are extensively validated for the detection of specific cell types derived from Peripheral Blood Mononuclear Cells (PBMCs) by flow cytometry. These antibodies enable accurate identification and profiling of immune cell subsets within PBMC populations, supporting diverse immunological studies and applications. These antibodies perform reliably in identifying critical immune cell subsets, including T cells, B cells, monocytes, and natural killer (NK) cells, providing essential tools for immunological and therapeutic research.

Comparative studies indicate that GeneMedi's antibody products offer performance on par with Company B's commercial antibodies. This similarity in performance means that researchers can expect comparable levels of sensitivity, specificity, and consistency when using GeneMedi's antibodies. Such equivalency provides researchers with confidence in using GeneMedi's products as effective alternatives, whether for immune profiling, cell population analysis, or functional assays.

Figure 1. GeneMedi's Anti-Human CD3E antibody, Anti-Human CD4 antibody, Anti-Human CD8 antibody, Anti-Human CD14 antibody, Anti-Human CD19 antibody, Anti-Human CD56 antibody, Anti-Human CD45 monoclonal antibody, Anti-Human CD66b monoclonal antibody and Anti-Human CD34 monoclonal antibody are validated to detect PBMC-derived specific cell types byflow cytometry.
A-F. Anti-Human CD3E antibody (A), Anti-Human CD4 antibody (B), Anti-Human CD8 antibody (C), Anti-Human CD14 antibody (D), Anti-Human CD19 antibody (E), Anti-Human NCAM1 (CD56) antibody (F). G. The Cat number and product name correspond to the antibodies used in this study.

cdex antibodies validation
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cdex-antibodies validation
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FMC64 and G4S Linker antibody validation

Figure 2. The GTU-ADA-FMC63-Ab01 and GMLS-Tag003-Ab-1 are validated to detect CAR-NK cells.

FMC64 antibody validation

Figure 3. The GTU-ADA-FMC63-Ab01 is validated to detect Simulate samples of CAR-NK infusion in patients.

G4S Linker antibody validation

Figure 4. For detecting CAR-T cells, GeneMedi's GMLS-Tag003-Ab-1 detection background is lower, and the detection results are closer to specific antigen detection, compared to Company C.

GMLS-Tag002-Ab01 effectively detects VHH-based format ant-Target CAR expression with great consistency with the target protein


Target protein (antigen) is usually used to detect anti-target CAR expression. For example, CD19 recombinant protein is used as a detection antigen for CAR position rate detection. However, the target protein is unique, expensive, and hard to produce. GeneMedi's anti-VHH antibody is a universal strategy for the detection of VHH-based format anti-Target CAR expression.

293T cells were transfected with CAR plasmids expressing VHH antibodies specific to target1, target2, target3, and target4. Following transfection, the expression of the corresponding CARs was confirmed using the specific recombinant proteins, GMLS-Tag002-Ab01, and a commercial Anti-VHH antibody (Company G).

The recombinant proteins were used as positive controls to benchmark CAR-positive detection. Statistical Analysis uses the positive detection ratio of GMLS-Tag002-Ab01 or Anti-VHH antibody (Company G) relative to the antigen-based detection. GMLS-Tag002-Ab01 achieves a consistency ratio close to 1.0. The data shows that the positive detection rate with GMLS-Tag002-Ab01 was comparable to that of the antigens, demonstrating nearly identical performance to the positive control. In contrast, the anti-VHH antibody (Company G) exhibited higher or lower detection sensitivity. The results indicate that GMLS-Tag002-Ab01 effectively detects the expressed VHH antibodies (nanobody, VHH-based bispecific antibody) on CAR-transfected 293T cells with high accuracy, comparable to the recombinant proteins. This establishes GMLS-Tag002-Ab01 as a reliable tool for detecting CAR expression in similar experiments.

VHH ELISA Validation
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Figure 5. GMLS-Tag002-Ab01 effectively evaluates the expression of anti-Target nanobody (VHH) on CAR-transfected 293T cells with higher specificity in flow cytometry.

A. The scatter plot shows the fluorescence intensity of CAR-expressing 293T cells stained with GMLS-Tag002-Ab01, Anti-VHH antibody (Company G), and the specific recombinant target protein (positive control).

B. GeneMedi's anti-VHH antibody shows great consistency with the antigen-based evaluation strategy in VHH-based format CAR expressing cell QC. Statistical Analysis uses the positive detection ratio of GMLS-Tag002-Ab01 or Anti-VHH antibody from Company G relative to the target protein-based detection.




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