TrueX® AAV Titration & Quantification Solution
Product Introduction & Advantages of TrueX® AAV Titration & Quantification Solution
GeneMedi's TrueX® AAV Titration & Quantification Solution offers a highly sensitive and robust ELISA-based platform designed for the precise measurement of intact Adeno-Associated Virus (AAV) capsids. Accurate titration is a critical quality attribute in gene and cell therapy development. The TrueX® series provides researchers and biomanufacturers with a reliable, standardized method to quantify AAV viral physical titers, ensuring consistency from early-stage discovery through to large-scale biomanufacturing.
TrueX® AAV Titration Solution
Key Advantages:
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· Serotype Precision — Engineered for distinct AAV serotypes (AAV2, AAV5, AAV6, AAV8, and AAV9) to deliver highly accurate intact capsid quantification.
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· Stable & Reliable Components — Reference standards and key reagents are supplied in a rigorously format to guarantee long-term stability, ensuring consistent lot-to-lot performance and reliable data.
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· High Sensitivity & Broad Dynamic Range — Optimized to detect viral particles efficiently, providing a robust analytical window suitable for both highly purified preparations and complex sample matrices.
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· Exceptional Reproducibility — Validated to minimize assay-to-assay variability, ensuring that your crucial analytical workflows remain stable and highly reproducible over time.
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· Streamlined Protocol — Features a user-friendly, standardized ELISA workflow that integrates seamlessly into existing laboratory operations, significantly reducing hands-on time and accelerating overall time-to-result.
Product list for TrueX® AAV Titration & Quantification Solution
| Product Type | Cat No | Product Name | Size | Products Information |
|---|---|---|---|---|
| AAV2 | GMV-TrueX-ELISA-2-1-96 | TrueX®-AAV2 Serotype Titration Kit (ELISA) | 1 plate/2 plate/5 plate/10 plates (96 wells) | Details |
| AAV5 | GMV-TrueX-ELISA-5-1-96 | TrueX®-AAV5 Serotype Titration Kit (ELISA) | 1 plate/2 plate/5 plate/10 plates (96 wells) | Details |
| AAV6 | GMV-TrueX-ELISA-6-1-96 | TrueX®- AAV6 Serotype Titration Kit (ELISA) | 1 plate/2 plate/5 plate/10 plates (96 wells) | Details |
| AAV8 | GMV-TrueX-ELISA-8-1-96 | TrueX®- AAV8 Serotype Titration Kit (ELISA) | 1 plate/2 plate/5 plate/10 plates (96 wells) | Details |
| AAV9 | GMV-TrueX-ELISA-9-1-96 | TrueX®-AAV9 Serotype Titration Kit (ELISA) | 1 plate/2 plate/5 plate/10 plates (96 wells) | Details |
Validation Data
- TrueX® - AAV Titration Kit (ELISA)
Figure 1. AAV2 capsid titration curve generated using the GenMedi AAV Titration ELISA kit
The table shows the standard concentrations of AAV 2 capsids (vp/ml) and their corresponding optical density (OD450) readings. The graph plots OD450 values against capsid concentrations, demonstrating a strong correlation (R² = 0.9998) between capsid quantity and absorbance, confirming the assay's sensitivity and accuracy.
Figure 2. AAV5 capsid titration curve generated using the GenMedi AAV Titration ELISA kit.
The table shows the standard concentrations of AAV 5 capsids (vp/ml) and their corresponding optical density (OD450) readings. The graph plots OD450 values against capsid concentrations, demonstrating a strong correlation (R² = 1.000) between capsid quantity and absorbance, confirming the assay's sensitivity and accuracy
Figure 3. AAV6 capsid titration curve generated using the GenMedi AAV Titration ELISA kit.
The table shows the standard concentrations of AAV 6 capsids (vp/ml) and their corresponding optical density (OD450) readings. The graph plots OD450 values against capsid concentrations, demonstrating a strong correlation (R² = 0.9997) between capsid quantity and absorbance, confirming the assay's sensitivity and accuracy.
Figure 4. AAV8 capsid titration curve generated using the GenMedi AAV Titration ELISA kit.
The table shows the standard concentrations of AAV 8 capsids (vp/ml) and their corresponding optical density (OD450) readings. The graph plots OD450 values against capsid concentrations, demonstrating a strong correlation (R² = 0.9997) between capsid quantity and absorbance, confirming the assay's sensitivity and accuracy.
Figure 5. AAV9 capsid titration curve generated using the GenMedi AAV Titration ELISA kit.
The table shows the standard concentrations of AAV 9 capsids (vp/ml) and their corresponding optical density (OD450) readings. The graph plots OD450 values against capsid concentrations, demonstrating a strong correlation (R² = 1.000) between capsid quantity and absorbance, confirming the assay's sensitivity and accuracy.
