The Kidneys are important to filter wastes and excess fluids from the blood and excreted in urine. Chronic kidney disease steadily loss the kidney function and fail to filter the waste in the body. The chronic kidney disease (CKD) includes advanced stage of renal parenchyma damage and the loss of functional nephrons. The loss of functional nephrons induces several molecular and cellular events, which leads to the development of renal lesions. The chronic kidney disease disperses the podocytes from basal membrane and excrete in the urine, therefore the diagnosis usually made with the serum proteins (creatinine) and blood urea (sCr). The early diagnosis of this disease is an important step to prevent the CKD. Biomarker such as Cystatin C (CYSC) Neutrophil gelatinase-associated lipocalin (NGAL)， Beta-2 microglobulin (B2M)， Alpha-1-microglobulin (A1M) and so on are suitable for monitoring CKD at early stages. Detecting the quantity of these marker proteins from different samples may benefit from ELISA, Lateral flow immunoassay (LFIA), colloidal gold immunochromatographic assay, Chemiluminescent immunoassay (CLIA), turbidimetric inhibition immuno assay (TINIA), immunonephelometry and POCT.

Genemedi supplies antibodies and antigens for kidney function (renal damages) testing for a wide selection of choices (please see below).

CYSC NGAL B2M A1M

Cystatin C (CYSC)

Cat No.	Antibody/Antigen Name	Expression platform	Isotypes	Bioactivity validation	Order
GMP-CYSC-Ag	Recombinant Cystatin C (CYSC, His Tag)	E.coli	Recombinant Antigen	Cystatin C (CYSC) Antibody Binding, Immunogen in Sandwich ELISA test, Lateral flow immunoassay (LFIA), colloidal gold immunochromatographic assay, Chemiluminescent immunoassay (CLIA),turbidimetric inhibition immuno assay (TINIA), immunonephelometry and POCT

Neutrophil gelatinase-associated lipocalin (NGAL)

Cat No.	Antibody/Antigen Name	Expression platform	Isotypes	Bioactivity validation	Order
GMP-NGAL-Ag; GMP-NGAL-Ab	Antigen: Recombinant Neutrophil gelatinase-associated lipocalin (NGAL, His Tag); Antibody: Anti-Neutrophil gelatinase-associated lipocalin (NGAL) Rabbit polyclonal antibody	Antigen: E.coli; Antibody: Rabbit serum	Antigen: Recombinant Antigen; Antibody: all	Antigen: Neutrophil gelatinase-associated lipocalin (NGAL) Antibody Binding; Antibody: human Neutrophil gelatinase-associated lipocalin (NGAL) protein binding, ELISA validated as capture antibody and detection antibody Pair in NGAL level test and kidney function (renal damages) evaluation.

Beta-2 microglobulin (B2M)

Cat No.	Antibody/Antigen Name	Expression platform	Isotypes	Bioactivity validation	Order
GMP-B2M-Ag; GMP-B2M-Ab	Antigen: Recombinant Beta-2 microglobulin (B2M, His Tag); Antibody: Anti-Beta-2 microglobulin (B2M) mouse monoclonal antibody(mAb)	Antigen: E.coli; Antibody:  Hybridoma	Antigen: Recombinant Antigen; Antibody: Mouse IgG	Antigen: Beta-2 microglobulin (B2M) Antibody Binding; Antibody: Human Beta-2 microglobulin (B2M) protein binding, ELISA validated as capture antibody and detection antibody. Pair in B2M level test and kidney function (renal damages) evaluation.

Alpha-1-microglobulin (A1M)

Cat No.	Antibody/Antigen Name	Expression platform	Isotypes	Bioactivity validation	Order
GMP-A1M-Ag	Recombinant Alpha-1-microglobulin (A1M, His Tag)	E.coli	Recombinant Antigen	Alpha-1-microglobulin (A1M) Antibody Binding, Immunogen in Sandwich ELISA test, Lateral flow immunoassay (LFIA),colloidal gold immunochromatographic assay, Chemiluminescent immunoassay (CLIA),turbidimetric inhibition immuno assay (TINIA), immunonephelometry and POCT