Diagnostic antibodies and antigens for kidney function (renal damages) testing: Beta-2 microglobulin (B2M), Cystatin C (CYSC), Neutrophil gelatinase-associated lipocalin (NGAL), Alpha-1-microglobulin (A1M)

The kidneys are important to filter wastes and excess fluids from the blood and excreted in urine. Chronic kidney disease steadily loss the kidney function and fail to filter the waste in the body. The chronic kidney disease (CKD) includes advanced stage of renal parenchyma damage and the loss of functional nephrons. The loss of functional nephrons induces several molecular and cellular events, which leads to the development of renal lesions. The chronic kidney disease disperses the podocytes from basal membrane and excrete in the urine, therefore the diagnosis usually made with the serum proteins (creatinine) and blood urea (sCr). The early diagnosis of this disease is an important step to prevent the CKD. Biomarker such as Cystatin C (CYSC) Neutrophil gelatinase-associated lipocalin (NGAL)，Beta-2 microglobulin (B2M)，Alpha-1-microglobulin (A1M) and so on are suitable for monitoring CKD at early stages. Detecting the quantity of these marker proteins from different samples may benefit from ELISA, Lateral flow immunoassay (LFIA), colloidal gold immunochromatographic assay, Chemiluminescent immunoassay (CLIA), turbidimetric inhibition immuno assay (TINIA), immunonephelometry and POCT.

Classification: B2M CYSC NGAL A1M

Beta-2 microglobulin (B2M)

Cat No.	Species	Biomarker	Disease	Cat No.of Antigen	Bioactivity validation of Antigen	Cat No.of Antibodies	Bioactivity validation of Antibodies	Order
GMP-h-B2M	Human	Beta-2 microglobulin (B2M)	renal disease	GMP-h-B2M-Ag01: Recombinant human B2M Protein	Beta-2 microglobulin (B2M) antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests,and other immunoassays as control material in B2M level test of Kidney function (renal damages)(renal disease) and related syndrome evaluation.	GMP-h-B2M-Ab01; GMP-h-B2M-Ab02: Anti-human B2M mouse monoclonal antibody(mAb)	Human Beta-2 microglobulin (B2M) antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other Beta-2 microglobulin (B2M) antibodies in B2M level test of Kidney function (renal damages) (renal disease) and related syndrome evaluation.

Cystatin C (CYSC)

Cat No.	Species	Biomarker	Disease	Cat No.of Antigen	Bioactivity validation of Antigen	Cat No.of Antibodies	Bioactivity validation of Antibodies	Order
GMP-h-CYSC	Human	Cystatin C (CYSC)	kidney function (renal damages)	GMP-h-CYSC-Ag01: Recombinant human CYSC Protein	Cystatin C (CYSC) antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests,and other immunoassays as control material in CYSC level test of Kidney function (renal damages)(kidney function (renal damages)) and related syndrome evaluation.	GMP-h-CYSC-Ab01; GMP-h-CYSC-Ab02: Anti-human CYSC mouse monoclonal antibody(mAb)	Human Cystatin C (CYSC) antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other Cystatin C (CYSC) antibodies in CYSC level test of Kidney function (renal damages) (kidney function (renal damages)) and related syndrome evaluation.

Neutrophil gelatinase-associated lipocalin (NGAL)

Cat No.	Species	Biomarker	Disease	Cat No.of Antigen	Bioactivity validation of Antigen	Cat No.of Antibodies	Bioactivity validation of Antibodies	Order
GMP-h-NGAL	Human	Neutrophil gelatinase-associated lipocalin (NGAL)	kidney injury	GMP-h-NGAL-Ag01: Recombinant human NGAL Protein	Neutrophil gelatinase-associated lipocalin (NGAL) antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests,and other immunoassays as control material in NGAL level test of Kidney function (renal damages)(kidney injury) and related syndrome evaluation.	GMP-h-NGAL-Ab01; GMP-h-NGAL-Ab02: Anti-human NGAL mouse monoclonal antibody(mAb)	Human Neutrophil gelatinase-associated lipocalin (NGAL) antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other Neutrophil gelatinase-associated lipocalin (NGAL) antibodies in NGAL level test of Kidney function (renal damages) (kidney injury) and related syndrome evaluation.

Alpha-1-microglobulin (A1M)

Cat No.	Species	Biomarker	Disease	Cat No.of Antigen	Bioactivity validation of Antigen	Cat No.of Antibodies	Bioactivity validation of Antibodies	Order
GMP-h-A1M	Human	Alpha-1-microglobulin (A1M)	Proteinuria, preeclampsia,	GMP-h-A1M-Ag01: Recombinant human A1M Protein	Alpha-1-microglobulin (A1M) antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests,and other immunoassays as control material in A1M level test of Kidney function (renal damages)(Proteinuria, preeclampsia,) and related syndrome evaluation.	GMP-h-A1M-Ab01; GMP-h-A1M-Ab02: Anti-human A1M mouse monoclonal antibody(mAb)	Human Alpha-1-microglobulin (A1M) antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other Alpha-1-microglobulin (A1M) antibodies in A1M level test of Kidney function (renal damages) (Proteinuria, preeclampsia,) and related syndrome evaluation.