Diagnostic antibodies and antigens for ruminant disease testing

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Ruminants continue to be important in their traditional role in agricultural. In addition, ruminants play a vital role in the economy of poor, deprived, backward classes, and landless labors of developing countries. To make this small ruminant-based economy viable and sustainable, development of techniques for early and accurate diagnosis holds prime importance. However, ruminants suffer from numerous diseases, namely, fowl cholera, atrophic rhinitis, transmissible spongiform encephalopathies (TSEs), abortion, akabane disease, bluetongue disease, borna disease, borrelia theileri infection, botulism, bovine amyloidosis, bovine besnoitiosis, bovine Parainfluenza-3 Virus (BPI3) infection, bovine respiratory syncytial virus infection, bovine spongiform encephalopathy, bovine viral diarrhea, calf enteritis, enzootic pneumonia complex, winter dysentery, campylobacteriosis, caprine arthritis encephalitis, caprine pleuropneumonia, chlamydiosis, traveler's diarrhea, chronic wasting disease, congenital diseases, contagious agalactia, contagious bovine pleuropneumonia, cystic hydatidosis, cysticercosis, enzootic bovine leukosis, fascioliasis, gastroenteritis, glanders, hemorrhagic septicemia, hormone disorders, hypodermiasis, immune dysfunction, leptospirosis, lumpy skin disease, maedi visna virus infection, mastitis, arthritis, pneumonia, nonbacterial diarrheic disease, paratuberculosis, paratuberculosis, PESTE des petits ruminants, pneumonia, prion associated diseases, Q fever, reproductive disease, respiratory disease, rift valley fever, rinderpest or cattle plague, rotaviral diarrhea, salmonellosis, schmallenberg disease, septicemia, septicemic colibacillosis, sexually transmitted infectious disease, trichomoniasis, tuberculosis/leprosy and so on. In such scenario, the rapid and specific detection of antigens and antibodies of these pathogens are developed by Genemedi. Detecting the quantity of marker proteins from different samples may benefit from ELISA, Lateral flow immunoassay (LFIA), colloidal gold immunochromatographic assay, Chemiluminescent immunoassay (CLIA), turbidimetric inhibition immuno assay (TINIA), immunonephelometry and POCT.

Classification: Bovines/Cattle Ovines/Sheep Caprine/Goat Deer

Diagnostic antibodies and antigens for bovines/cattle infectious and non-infectious disease testing

Cattle diseases cost millions of money losses every year. In addition to death, they cause loss of production and frequently a loss of body condition. Unhealthy animals require more food and take longer time for growth than healthy ones. Generally, animals are born free of diseases or parasites. But they usually acquire these diseases either through contact with diseased animals or due to improper sanitation, feeding, care and management. Knowledge of cattle diseases is necessary from public health point of view also as many diseases can be transmitted to man through milk. Keeping animals healthy by employing sound principles of sanitation, management and feeding and by judicious use of appropriate and dependable vaccines are the practical and economical ways to avoid losses from the disease. By proper management and feeding, the dairy farmer can, to a great extent, prevent disease out-breaks. Cattle are infected by a community of endemic pathogens with different epidemiological properties that invoke different managerial and governmental responses. Genemedi developed the antigen and antibody to detect the abortion, acute severe metritis, borna disease, borrelia theileri infection, bovine amyloidosis, bovine besnoitiosis, bovine parainfluenza-3 virus (bpi3) infection, bovine respiratory syncytial virus infection, bovine spongiform encephalopathy, bovine viral diarrhea, calf enteritis, chronic endometritis, chronic wasting disease, contagious bovine pleuropneumonia, cystic hydatidosis, cysticercosis, diarrhea, enzootic bovine leukosis, enzootic pneumonia complex, gastrointestinal infections, hormone disorders, hypodermiasis, infectious bovine rhinotracheitis, infectious pustular vulvovaginitis, ketosis, mastitis, arthritis and pneumonia, milk fever, paratuberculosis, respiratory and enteric infections, respiratory syndrome, retained placenta, rotaviral diarrhea, septicemia, severe mastitis, systemic infection in neonates, thromboembolic meningoencepahlitis (teme), transmissible spongiform encephalopathies (tses), tuberculosis/leprosy and so on.

Due to the physiology and structure of bovines, cattle health issues are also unique. With their four-chambered stomachs and a surprising susceptibility to heat, cattle require special care, monitoring and handling to maintain optimum health and longevity. Good grassland management will ensure that cattle have access to plenty of leafy grass that they can readily digest and will provide all of their energy requirements for maintenance and growth. In addition, the diet must also provide small amounts of certain essential chemical elements (trace elements). Deficiencies of any of these micronutrients can result in ill-thrift. Fortunately, there are a few simple ways to improve your herd’s health. Watchful ranchers can detect early signs of the most common cattle health issues, and then take preventative measures to correct potentially detrimental conditions. Genemedi developed the antigen and antibody to detect the non-infectious disease such as immune dysfunction, abortion and teratology, nonbacterial diarrheic disease, Prion associated diseases (Scrapie, Bovine Spongiform Encephalopathy, Chronical Waste Disease), winter dysentery and so on.

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