GATA3: Target/Biomarker Introduction, products summarized (antibody/ADC/bispecific/antigen/ORF vector/VLP) and disease/indication/condition/MOA for drug discovery and IVD
It's the GeneMedi's summary page for Target/Biomarker Introduction of GATA3. The page also collects GeneMedi's different modalities and formats products for GATA3 in therapeutics/drug discovery and IVD diagnostics, which is including antibody, ADC, bispecific, antigen, ORF vector, VLP, etc. With GeneMedi's target-insight database-GM ITD database, the GATA3 target is also connected to human indications/diseases/conditions/MOA.
Target sublocation: Introcelluar Protein.
This gene encodes a protein which belongs to the GATA family of transcription factors. The protein contains two GATA-type zinc fingers and is an important regulator of T-cell development and plays an important role in endothelial cell biology. Defects in this gene are the cause of hypoparathyroidism with sensorineural deafness and renal dysplasia. [provided by RefSeq, Nov 2009]
Target ID | GM-T92635 |
Target Name | GATA3 |
Gene ID | 2625,14462,85471,713840,487134,101083271,505169,100069946 |
Gene Symbol and Synonyms | Gata-3,GATA3,HDR,HDRS,jal |
Uniprot Accession | P23771,Q08DV0 |
Uniprot Entry Name | GATA3_HUMAN,GATA3_BOVIN |
Protein Sub-location | Introcelluar Protein |
Category | Therapeutics Target |
Disease | Cancer |
Gene Ensembl | ENSG00000107485 |
Target Classification | Tumor-associated antigen (TAA) |
Pre-made anti-GATA3 inhibitory monoclonal antibody(mab, blocking antibody inhibitor)-benchmark antibody for drug discovery and mechanism of action (MOA) research
Pre-made anti-GATA3 monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). The anti-GATA3 mab is expressed and produced by mammalian cell line as a benchmark reference therapeutic antibody for biological drug discovery items including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Antibody Name | Species | Format | Classified by tag | Detail |
Anti-GATA3 monoclonal antibody | Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine | mab | Therapeutics Target antibody | Detail |
Recombinant multi-species GATA3/ HDR/ HDRS protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis
Genemedi produces Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine GATA3 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
Products Name | Species | Expression Platform | Detail |
GATA3 protein | Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine | Mammalian cell | Detail |
Pre-made GATA3 viral vector in GM Promise-ORFTM
Cat No. | Products name | NM ID | Species | Type | Detail |
vGMAP000541 | human GATA3 Adenovirus particle | BC006793 | Human | Adenovirus particle | Detail |
vGMLP003900 | human GATA3 Lentivirus particle | BC006793.1 | Human | Lentivirus particle | Detail |
pGMAP000541 | human GATA3 Adenovirus plasmid | BC006793 | Human | Adenovirus plasmid | Detail |
pGMLP003900 | human GATA3 Lentivirus plasmid | BC006793.1 | Human | Lentivirus plasmid | Detail |
vGMLP001387 | human GATA3 Lentivirus particle | NM_001002295 | Human | Lentivirus particle | Detail |
pGMLP001387 | human GATA3 Lentivirus plasmid | NM_001002295 | Human | Lentivirus plasmid | Detail |
pGMLPm002654 | mouse Gata3 Lentivirus plasmid | NM_001355110 | Mouse | Lentivirus plasmid | Detail |
pGMLPm005445 | mouse Gata3 Lentivirus plasmid | XM_006497355.3 | Mouse | Lentivirus plasmid | Detail |
vGMLPm002654 | mouse Gata3 Lentivirus particle | NM_001355110 | Mouse | Lentivirus particle | Detail |
vGMLPm005445 | mouse Gata3 Lentivirus particle | XM_006497355.3 | Mouse | Lentivirus particle | Detail |
About Promise-ORFTM:
Discover the largest collection of ORF/cDNA expression clones from different species, including human, mouse, rat, and more with GeneMedi's Promise-ORFTM. Our collection of ORFs expression clones come in verified mammalian or viral vectors lentivirus, AAV, and adenovirus) and our Promise-ORFTM viral-ready expression vectors make it easy for you to improve viral vector packaging efficiency or directly transfect mammalian cells, resulting in stronger and easier expression detection. Click to search your GOI
If you want to obtain higher quantities of plasmids (mg), please visit GM TransExcellent Plasmid DNA Rapid Preparation Service.