BNIP3: Target/Biomarker Introduction, products summarized (antibody/ADC/bispecific/antigen/ORF vector/VLP) and disease/indication/condition/MOA for drug discovery and IVD
It's the GeneMedi's summary page for Target/Biomarker Introduction of BNIP3. The page also collects GeneMedi's different modalities and formats products for BNIP3 in therapeutics/drug discovery and IVD diagnostics, which is including antibody, ADC, bispecific, antigen, ORF vector, VLP, etc. With GeneMedi's target-insight database-GM ITD database, the BNIP3 target is also connected to human indications/diseases/conditions/MOA.
Target sublocation: Introcelluar Protein.
This gene is encodes a mitochondrial protein that contains a BH3 domain and acts as a pro-apoptotic factor. The encoded protein interacts with anti-apoptotic proteins, including the E1B 19 kDa protein and Bcl2. This gene is silenced in tumors by DNA methylation. [provided by RefSeq, Dec 2014]
Target ID | GM-IP0426 |
Target Name | BNIP3 |
Gene ID | 664,12176,84480,100426120,607408,768094,615342,100051673 |
Gene Symbol and Synonyms | BNIP3,HABON,NIP3 |
Uniprot Accession | Q12983,Q32KN2 |
Uniprot Entry Name | BNIP3_HUMAN,BNIP3_BOVIN |
Protein Sub-location | Introcelluar Protein |
Category | |
Disease | Cancer |
Gene Ensembl | ENSG00000176171 |
Target Classification | Tumor-associated antigen (TAA) |
Pre-made anti-BNIP3 inhibitory monoclonal antibody(mab, blocking antibody inhibitor)-benchmark antibody for drug discovery and mechanism of action (MOA) research
Pre-made anti-BNIP3 monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). The anti-BNIP3 mab is expressed and produced by mammalian cell line as a benchmark reference therapeutic antibody for biological drug discovery items including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Antibody Name | Species | Format | Classified by tag | Detail |
Anti-BNIP3 monoclonal antibody | Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine | mab | Detail |
Recombinant multi-species BNIP3/ NIP3 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis
Genemedi produces Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine BNIP3 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
Products Name | Species | Expression Platform | Detail |
BNIP3 protein | Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine | Mammalian cell | Detail |
Pre-made BNIP3 viral vector in GM Promise-ORFTM
Cat No. | Products name | NM ID | Species | Type | Detail |
vGMAD000162 | human BNIP3 Adenovirus particle | NM_004052.3 | Human | Adenovirus particle | Detail |
vGMLPm004024 | mouse BNIP3 Lentivirus particle | NM_004052.3 | Mouse | Lentivirus particle | Detail |
pGMAD000162 | human BNIP3 Adenovirus plasmid | NM_004052.3 | Human | Adenovirus plasmid | Detail |
pGMLPm004024 | mouse BNIP3 Lentivirus plasmid | NM_004052.3 | Mouse | Lentivirus plasmid | Detail |
pGMLPm000005 | mouse Bnip3 Lentivirus plasmid | NM_009760 | Mouse | Lentivirus plasmid | Detail |
vGMLPm000005 | mouse Bnip3 Lentivirus particle | NM_009760 | Mouse | Lentivirus particle | Detail |
About Promise-ORFTM:
Discover the largest collection of ORF/cDNA expression clones from different species, including human, mouse, rat, and more with GeneMedi's Promise-ORFTM. Our collection of ORFs expression clones come in verified mammalian or viral vectors lentivirus, AAV, and adenovirus) and our Promise-ORFTM viral-ready expression vectors make it easy for you to improve viral vector packaging efficiency or directly transfect mammalian cells, resulting in stronger and easier expression detection. Click to search your GOI
If you want to obtain higher quantities of plasmids (mg), please visit GM TransExcellent Plasmid DNA Rapid Preparation Service.