CAV3: Target/Biomarker Introduction, products summarized (antibody/ADC/bispecific/antigen/ORF vector/VLP) and disease/indication/condition/MOA for drug discovery and IVD
It's the GeneMedi's summary page for Target/Biomarker Introduction of CAV3. The page also collects GeneMedi's different modalities and formats products for CAV3 in therapeutics/drug discovery and IVD diagnostics, which is including antibody, ADC, bispecific, antigen, ORF vector, VLP, etc. With GeneMedi's target-insight database-GM ITD database, the CAV3 target is also connected to human indications/diseases/conditions/MOA.
Target sublocation: Transmembrane Protein.
This gene encodes a caveolin family member, which functions as a component of the caveolae plasma membranes found in most cell types. Caveolin proteins are proposed to be scaffolding proteins for organizing and concentrating certain caveolin-interacting molecules. Mutations identified in this gene lead to interference with protein oligomerization or intra-cellular routing, disrupting caveolae formation and resulting in Limb-Girdle muscular dystrophy type-1C (LGMD-1C), hyperCKemia or rippling muscle disease (RMD). Alternative splicing has been identified for this locus, with inclusion or exclusion of a differentially spliced intron. In addition, transcripts utilize multiple polyA sites and contain two potential translation initiation sites. [provided by RefSeq, Jul 2008]
Target ID | GM-MP0187 |
Target Name | CAV3 |
Gene ID | 859,12391,29161,702163,484671,101081453,615310,100058881 |
Gene Symbol and Synonyms | Cav-3,CAV3,LGMD1C,LQT9,M-cav,MPDT,RMD2,VIP-21,VIP21 |
Uniprot Accession | P56539,P51638,Q2KI43 |
Uniprot Entry Name | CAV3_HUMAN,CAV3_RAT,CAV3_BOVIN |
Protein Sub-location | Transmembrane Protein |
Category | |
Disease | N/A |
Gene Ensembl | ENSG00000182533 |
Target Classification | N/A |
Pre-made anti-CAV3 inhibitory monoclonal antibody(mab, blocking antibody inhibitor)-benchmark antibody for drug discovery and mechanism of action (MOA) research
Pre-made anti-CAV3 benchmark inhibitory monoclonal antibody(mab, blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). The anti-CAV3 mab is expressed and produced by mammalian cell line as a benchmark reference therapeutic antibody for biological drug discovery items including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Antibody Name | Species | Format | Classified by tag | Detail |
Anti-CAV3 monoclonal antibody | Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine | mab | FACS/Biofunctional Antibody | Detail |
Multi-species CAV3/ LGMD1C/ LQT9 VLP (virus-like particle) for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis
Genemedi produces Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine CAV3 VLP (virus-like particle) for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
Products Name | Species | Expression Platform | Detail |
CAV3 VLP (virus-like particle) | Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine | Mammalian cell | Products Developing |
Pre-made CAV3 viral vector in GM Promise-ORFTM
Cat No. | Products name | NM ID | Species | Type | Detail |
pGMLP002892 | human CAV3 Lentivirus plasmid | NM_033337 | Human | Lentivirus plasmid | Detail |
vGMLP002892 | human CAV3 Lentivirus particle | NM_033337 | Human | Lentivirus particle | Detail |
pGMAD000634 | Norway rat Cav3 Adenovirus plasmid | NM_019155 | Norway Rat | Adenovirus plasmid | Detail |
pGMAAV000277 | Norway rat Cav3 AAV plasmid | NM_019155.2 | Norway Rat | AAV plasmid | Detail |
pGMAAV000361 | house mouse Cav3 AAV plasmid | NM_007617 | House Mouse | AAV plasmid | Detail |
pGMLPm001557 | mouse Cav3 Lentivirus plasmid | NM_007617 | Mouse | Lentivirus plasmid | Detail |
vGMAD000634 | Norway rat Cav3 Adenovirus particle | NM_019155 | Norway Rat | Adenovirus particle | Detail |
vGMAAV000277 | Norway rat Cav3 AAV particle | NM_019155.2 | Norway Rat | AAV particle | Detail |
vGMAAV000361 | house mouse Cav3 AAV particle | NM_007617 | House Mouse | AAV particle | Detail |
vGMLPm001557 | mouse Cav3 Lentivirus particle | NM_007617 | Mouse | Lentivirus particle | Detail |
About Promise-ORFTM:
Discover the largest collection of ORF/cDNA expression clones from different species, including human, mouse, rat, and more with GeneMedi's Promise-ORFTM. Our collection of ORFs expression clones come in verified mammalian or viral vectors lentivirus, AAV, and adenovirus) and our Promise-ORFTM viral-ready expression vectors make it easy for you to improve viral vector packaging efficiency or directly transfect mammalian cells, resulting in stronger and easier expression detection. Click to search your GOI
If you want to obtain higher quantities of plasmids (mg), please visit GM TransExcellent Plasmid DNA Rapid Preparation Service.