c-Fos/FOS: Target/Biomarker Introduction, products summarized (antibody/ADC/bispecific/antigen/ORF vector/VLP) and disease/indication/condition/MOA for drug discovery and IVD

It's the GeneMedi's summary page for Target/Biomarker Introduction of c-Fos/FOS. The page also collects GeneMedi's different modalities and formats products for c-Fos in therapeutics/drug discovery and IVD diagnostics, which is including antibody, ADC, bispecific, antigen, ORF vector, VLP, etc. With GeneMedi's target-insight database-GM ITD database, the c-Fos target is also connected to human indications/diseases/conditions/MOA.

Target sublocation: Introcelluar Protein.

The Fos gene family consists of 4 members: FOS, FOSB, FOSL1, and FOSL2.? These genes encode leucine zipper proteins that can dimerize with proteins of the JUN family, thereby forming the transcription factor complex AP-1.? As such, the FOS proteins have been implicated as regulators of cell proliferation, differentiation, and transformation.? In some cases, expression of the FOS gene has also been associated with apoptotic cell death. [provided by RefSeq, Jul 2008]

Target IDGM-T28025
Target Namec-Fos
Gene ID2353,14281,314322,702077,490792,493935,280795,100051632
Gene Symbol and SynonymsAP-1,C-FOS,cFos,D12Rfj1,FOS,p55
Uniprot AccessionP01100,P12841,Q8HZP6,O77628
Uniprot Entry NameFOS_HUMAN,FOS_RAT,FOS_FELCA,FOS_BOVIN
Protein Sub-locationIntrocelluar Protein
CategoryTherapeutics Target
DiseaseCancer
Gene EnsemblENSG00000170345
Target ClassificationTumor-associated antigen (TAA)


Pre-made anti-c-Fos inhibitory monoclonal antibody(mab, blocking antibody inhibitor)-benchmark antibody for drug discovery and mechanism of action (MOA) research

Pre-made anti-c-Fos monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). The anti-c-Fos mab is expressed and produced by mammalian cell line as a benchmark reference therapeutic antibody for biological drug discovery items including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.

Antibody NameSpeciesFormatClassified by tagDetail
Anti-c-Fos/FOS monoclonal antibodyHuman, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, EquinemabTherapeutics Target antibodyDetail



Recombinant multi-species FOS/ c-Fos/ AP-1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine c-Fos/FOS protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.

Products NameSpeciesExpression PlatformDetail
c-Fos/FOS proteinHuman, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, EquineMammalian cellDetail



Pre-made FOS viral vector in GM Promise-ORFTM

Cat No.Products nameNM IDSpeciesTypeDetail
pGMLP001940human FOS Lentivirus plasmidNM_005252.3HumanLentivirus plasmidDetail
vGMAP000475Human FOS Adenovirus particleBC004490HumanAdenovirus particleDetail
vGMAD000494human FOS Adenovirus particleNM_005252.3HumanAdenovirus particleDetail
vGMLP001940human FOS Lentivirus particleNM_005252.3HumanLentivirus particleDetail
pGMAP000475Human FOS Adenovirus plasmidBC004490HumanAdenovirus plasmidDetail
pGMAD000494human FOS Adenovirus plasmidNM_005252.3HumanAdenovirus plasmidDetail
pGMLPm002314mouse Fos Lentivirus plasmidNM_010234MouseLentivirus plasmidDetail
vGMLPm002314mouse Fos Lentivirus particleNM_010234MouseLentivirus particleDetail

About Promise-ORFTM:
Discover the largest collection of ORF/cDNA expression clones from different species, including human, mouse, rat, and more with GeneMedi's Promise-ORFTM. Our collection of ORFs expression clones come in verified mammalian or viral vectors lentivirus, AAV, and adenovirus) and our Promise-ORFTM viral-ready expression vectors make it easy for you to improve viral vector packaging efficiency or directly transfect mammalian cells, resulting in stronger and easier expression detection. Click to search your GOI

If you want to obtain higher quantities of plasmids (mg), please visit GM TransExcellent Plasmid DNA Rapid Preparation Service.






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