TXN: Target/Biomarker Introduction, products summarized (antibody/ADC/bispecific/antigen/ORF vector/VLP) and disease/indication/condition/MOA for drug discovery and IVD

It's the GeneMedi's summary page for Target/Biomarker Introduction of TXN. The page also collects GeneMedi's different modalities and formats products for TXN in therapeutics/drug discovery and IVD diagnostics, which is including antibody, ADC, bispecific, antigen, ORF vector, VLP, etc. With GeneMedi's target-insight database-GM ITD database, the TXN target is also connected to human indications/diseases/conditions/MOA.

Target sublocation: Secreted Protein/Potential Cytokines.

The protein encoded by this gene acts as a homodimer and is involved in many redox reactions. The encoded protein is active in the reversible S-nitrosylation of cysteines in certain proteins, which is part of the response to intracellular nitric oxide. This protein is found in the cytoplasm. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]

Target IDGM-T85616
Target NameTXN
Gene ID7295,22166,116484,712587,474798,101090655,280950,100033827
Gene Symbol and SynonymsADF,TRDX,TRX,TRX1,Trx80,TXN,TXN1
Uniprot AccessionP10599,P11232,P29451,P99505,O97680,O97508
Uniprot Entry NameTHIO_HUMAN,THIO_MACMU,THIO_RAT,THIO_CANLF,THIO_BOVIN,THIO_HORSE
Protein Sub-locationSecreted Protein/Potential Cytokines
CategoryTherapeutics Target
DiseaseN/A
Gene EnsemblENSG00000136810
Target ClassificationN/A


Pre-made anti-TXN inhibitory monoclonal antibody(mab, blocking antibody inhibitor)-benchmark antibody for drug discovery and mechanism of action (MOA) research

Pre-made anti-TXN benchmark inhibitory monoclonal antibody(mab, blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). The anti-TXN mab is expressed and produced by mammalian cell line as a benchmark reference therapeutic antibody for biological drug discovery items including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.

Antibody NameSpeciesFormatClassified by tagDetail
Anti-TXN monoclonal antibodyHuman, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, EquinemabFACS/Biofunctional Antibody, Therapeutics Target antibodyDetail



Recombinant multi-species THIO/ TXN/ TRDX protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine TXN protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.

Products NameSpeciesExpression PlatformDetail
TXN proteinHuman, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, EquineMammalian cellDetail



Pre-made TXN viral vector in GM Promise-ORFTM

Cat No.Products nameNM IDSpeciesTypeDetail
vGMAD000153human TXN Adenovirus particleNM_003329HumanAdenovirus particleDetail
vGMLP000876human TXN Lentivirus particleNM_003329.3HumanLentivirus particleDetail
pGMAD000153human TXN Adenovirus plasmidNM_003329HumanAdenovirus plasmidDetail
pGMLP000876human TXN Lentivirus plasmidNM_003329.3HumanLentivirus plasmidDetail
pGMAD000538Norway rat Txn1 Adenovirus plasmidNM_053800.3Norway RatAdenovirus plasmidDetail
pGMAAV000207house mouse Txn1 AAV plasmidNM_011660.3House MouseAAV plasmidDetail
pGMLPm002205mouse Txn1 Lentivirus plasmidNM_011660MouseLentivirus plasmidDetail
vGMAD000538Norway rat Txn1 Adenovirus particleNM_053800.3Norway RatAdenovirus particleDetail
vGMAAV000207house mouse Txn1 AAV particleNM_011660.3House MouseAAV particleDetail
vGMLPm002205mouse Txn1 Lentivirus particleNM_011660MouseLentivirus particleDetail

About Promise-ORFTM:
Discover the largest collection of ORF/cDNA expression clones from different species, including human, mouse, rat, and more with GeneMedi's Promise-ORFTM. Our collection of ORFs expression clones come in verified mammalian or viral vectors lentivirus, AAV, and adenovirus) and our Promise-ORFTM viral-ready expression vectors make it easy for you to improve viral vector packaging efficiency or directly transfect mammalian cells, resulting in stronger and easier expression detection. Click to search your GOI

If you want to obtain higher quantities of plasmids (mg), please visit GM TransExcellent Plasmid DNA Rapid Preparation Service.






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