HMOX1: Target/Biomarker Introduction, products summarized (antibody/ADC/bispecific/antigen/ORF vector/VLP) and disease/indication/condition/MOA for drug discovery and IVD

It's the GeneMedi's summary page for Target/Biomarker Introduction of HMOX1. The page also collects GeneMedi's different modalities and formats products for HMOX1 in therapeutics/drug discovery and IVD diagnostics, which is including antibody, ADC, bispecific, antigen, ORF vector, VLP, etc. With GeneMedi's target-insight database-GM ITD database, the HMOX1 target is also connected to human indications/diseases/conditions/MOA.

Target sublocation: Introcelluar Protein.

Heme oxygenase, an essential enzyme in heme catabolism, cleaves heme to form biliverdin, which is subsequently converted to bilirubin by biliverdin reductase, and carbon monoxide, a putative neurotransmitter. Heme oxygenase activity is induced by its substrate heme and by various nonheme substances. Heme oxygenase occurs as 2 isozymes, an inducible heme oxygenase-1 and a constitutive heme oxygenase-2. HMOX1 and HMOX2 belong to the heme oxygenase family. [provided by RefSeq, Jul 2008]

Target IDGM-IP0044
Target NameHMOX1
Gene ID3162,15368,24451,719266,442987,101092621,513221,100069058
Gene Symbol and SynonymsbK286B10,D8Wsu38e,Hemox,Heox,HEOXG,Hmox,HMOX1,HMOX1D,HO-1,HO1,HSP32
Uniprot AccessionP09601,P06762,Q5E9F2
Uniprot Entry NameHMOX1_HUMAN,HMOX1_RAT,HMOX1_BOVIN
Protein Sub-locationIntrocelluar Protein
CategoryTherapeutics Target
DiseaseAcute kidney failure, Renal tubulo-interstitial diseases
Gene EnsemblENSG00000100292
Target ClassificationN/A


Pre-made anti-HMOX1 inhibitory monoclonal antibody(mab, blocking antibody inhibitor)-benchmark antibody for drug discovery and mechanism of action (MOA) research

Pre-made anti-HMOX1 monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). The anti-HMOX1 mab is expressed and produced by mammalian cell line as a benchmark reference therapeutic antibody for biological drug discovery items including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.

Antibody NameSpeciesFormatClassified by tagDetail
Anti-HMOX1 monoclonal antibodyHuman, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, EquinemabTherapeutics Target antibodyDetail



Recombinant multi-species HMOX1/ HMOX1D/ HO-1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine HMOX1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.

Products NameSpeciesExpression PlatformDetail
HMOX1 proteinHuman, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, EquineMammalian cellDetail



Pre-made HMOX1 viral vector in GM Promise-ORFTM

Cat No.Products nameNM IDSpeciesTypeDetail
pGMLV000774human HMOX1 Lentivirus plasmidNM_002133.2HumanLentivirus plasmidDetail
pGMLP003511human HMOX1 Lentivirus plasmidNM_002133HumanLentivirus plasmidDetail
pGMLV000303human HMOX1 Lentivirus plasmidNM_002133.2HumanLentivirus plasmidDetail
vGMLP003511human HMOX1 Lentivirus particleNM_002133HumanLentivirus particleDetail
vGMLV000774human HMOX1 Lentivirus particleNM_002133.2HumanLentivirus particleDetail
pGMLV000302human HMOX1 Lentivirus plasmidNM_002133.2HumanLentivirus plasmidDetail
vGMLV000303human HMOX1 Lentivirus particleNM_002133.2HumanLentivirus particleDetail
vGMLV000302human HMOX1 Lentivirus particleNM_002133.2HumanLentivirus particleDetail
pGMLV000149mouse Hmox1 Lentivirus plasmidNM_010442.2MouseLentivirus plasmidDetail
pGMAD000236mouse Hmox1 Adenovirus plasmidNM_010442.2MouseAdenovirus plasmidDetail
pGMAD000251rat Hmox1 Adenovirus plasmidNM_012580.2RatAdenovirus plasmidDetail
pGMAAV000324Norway rat Hmox1 AAV plasmidNM_012580Norway RatAAV plasmidDetail
vGMLV000149mouse Hmox1 Lentivirus particleNM_010442.2MouseLentivirus particleDetail
vGMAD000236mouse Hmox1 Adenovirus particleNM_010442.2MouseAdenovirus particleDetail
vGMAD000251rat Hmox1 Adenovirus particleNM_012580.2RatAdenovirus particleDetail
vGMAAV000324Norway rat Hmox1 AAV particleNM_012580Norway RatAAV particleDetail

About Promise-ORFTM:
Discover the largest collection of ORF/cDNA expression clones from different species, including human, mouse, rat, and more with GeneMedi's Promise-ORFTM. Our collection of ORFs expression clones come in verified mammalian or viral vectors lentivirus, AAV, and adenovirus) and our Promise-ORFTM viral-ready expression vectors make it easy for you to improve viral vector packaging efficiency or directly transfect mammalian cells, resulting in stronger and easier expression detection. Click to search your GOI

If you want to obtain higher quantities of plasmids (mg), please visit GM TransExcellent Plasmid DNA Rapid Preparation Service.






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