Anti-HMOX1 monoclonal antibody

Pre-made anti-HMOX1 monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research

Target products collectionGo to HMOX1/HMOX1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-IP0044-Ab-1/ GM-Tg-hg-IP0044-Ab-2Anti-Human HMOX1 monoclonal antibodyHuman
GM-Tg-rg-IP0044-Ab-1/ GM-Tg-rg-IP0044-Ab-2Anti-Rat HMOX1 monoclonal antibodyRat
GM-Tg-mg-IP0044-Ab-1/ GM-Tg-mg-IP0044-Ab-2Anti-Mouse HMOX1 monoclonal antibodyMouse
GM-Tg-cynog-IP0044-Ab-1/ GM-Tg-cynog-IP0044-Ab-2Anti-Cynomolgus/ Rhesus macaque HMOX1 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-IP0044-Ab-1/ GM-Tg-felg-IP0044-Ab-2Anti-Feline HMOX1 monoclonal antibodyFeline
GM-Tg-cang-IP0044-Ab-1/ GM-Tg-cang-IP0044-Ab-2Anti-Canine HMOX1 monoclonal antibodyCanine
GM-Tg-bovg-IP0044-Ab-1/ GM-Tg-bovg-IP0044-Ab-2Anti-Bovine HMOX1 monoclonal antibodyBovine
GM-Tg-equg-IP0044-Ab-1/ GM-Tg-equg-IP0044-Ab-2Anti-Equine HMOX1 monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-IP0044-Ab-1/ GM-Tg-hg-IP0044-Ab-2; GM-Tg-rg-IP0044-Ab-1/ GM-Tg-rg-IP0044-Ab-2;
GM-Tg-mg-IP0044-Ab-1/ GM-Tg-mg-IP0044-Ab-2; GM-Tg-cynog-IP0044-Ab-1/ GM-Tg-cynog-IP0044-Ab-2;
GM-Tg-felg-IP0044-Ab-1/ GM-Tg-felg-IP0044-Ab-2; GM-Tg-cang-IP0044-Ab-1/ GM-Tg-cang-IP0044-Ab-2;
GM-Tg-bovg-IP0044-Ab-1/ GM-Tg-bovg-IP0044-Ab-2; GM-Tg-equg-IP0044-Ab-1/ GM-Tg-equg-IP0044-Ab-2
Products NameAnti-HMOX1 monoclonal antibody
Formatmab
Target NameHMOX1
Protein Sub-locationIntrocelluar Protein
Category of antibodyTherapeutics Target antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected.
TagFc
Products descriptionPre-made anti-HMOX1 monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation Lyophilized from sterile PBS, PH 7.4
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


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    Associated products


    CategoryCat No.Products Name
    Target AntigenGM-Tg-g-IP0044-Ag-1Recombinant multi-species HMOX1/ HMOX1D/ HO-1 protein
    ORF Viral VectorpGMLV000774human HMOX1 Lentivirus plasmid
    ORF Viral VectorpGMLP003511human HMOX1 Lentivirus plasmid
    ORF Viral VectorpGMLV000303human HMOX1 Lentivirus plasmid
    ORF Viral VectorvGMLP003511human HMOX1 Lentivirus particle
    ORF Viral VectorvGMLV000774human HMOX1 Lentivirus particle
    ORF Viral VectorpGMLV000302human HMOX1 Lentivirus plasmid
    ORF Viral VectorvGMLV000303human HMOX1 Lentivirus particle
    ORF Viral VectorvGMLV000302human HMOX1 Lentivirus particle
    ORF Viral VectorpGMLV000149mouse Hmox1 Lentivirus plasmid
    ORF Viral VectorpGMAD000236mouse Hmox1 Adenovirus plasmid
    ORF Viral VectorpGMAD000251rat Hmox1 Adenovirus plasmid
    ORF Viral VectorpGMAAV000324Norway rat Hmox1 AAV plasmid
    ORF Viral VectorvGMLV000149mouse Hmox1 Lentivirus particle
    ORF Viral VectorvGMAD000236mouse Hmox1 Adenovirus particle
    ORF Viral VectorvGMAD000251rat Hmox1 Adenovirus particle
    ORF Viral VectorvGMAAV000324Norway rat Hmox1 AAV particle


    Target information

    Target IDGM-IP0044
    Target NameHMOX1
    Gene ID3162,15368,24451,719266,442987,101092621,513221,100069058
    Gene Symbol and SynonymsbK286B10,D8Wsu38e,Hemox,Heox,HEOXG,Hmox,HMOX1,HMOX1D,HO-1,HO1,HSP32
    Uniprot AccessionP09601,P06762,Q5E9F2
    Uniprot Entry NameHMOX1_HUMAN,HMOX1_RAT,HMOX1_BOVIN
    Protein Sub-locationIntrocelluar Protein
    CategoryTherapeutics Target
    DiseaseAcute kidney failure, Renal tubulo-interstitial diseases
    Gene EnsemblENSG00000100292
    Target ClassificationN/A

    The target: HMOX1, gene name: HMOX1, also named as HMOX1D, HO-1, HSP32, bK286B10. Heme oxygenase, an essential enzyme in heme catabolism, cleaves heme to form biliverdin, which is subsequently converted to bilirubin by biliverdin reductase, and carbon monoxide, a putative neurotransmitter. Heme oxygenase activity is induced by its substrate heme and by various nonheme substances. Heme oxygenase occurs as 2 isozymes, an inducible heme oxygenase-1 and a constitutive heme oxygenase-2. HMOX1 and HMOX2 belong to the heme oxygenase family. [provided by RefSeq, Jul 2008].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.