PACAP-38/ADCYAP1: Target/Biomarker Introduction, products summarized (antibody/ADC/bispecific/antigen/ORF vector/VLP) and disease/indication/condition/MOA for drug discovery and IVD
It's the GeneMedi's summary page for Target/Biomarker Introduction of PACAP-38/ADCYAP1. The page also collects GeneMedi's different modalities and formats products for PACAP-38 in therapeutics/drug discovery and IVD diagnostics, which is including antibody, ADC, bispecific, antigen, ORF vector, VLP, etc. With GeneMedi's target-insight database-GM ITD database, the PACAP-38 target is also connected to human indications/diseases/conditions/MOA.
Target sublocation: Secreted Protein/Potential Cytokines.
This gene encodes a secreted proprotein that is further processed into multiple mature peptides. These peptides stimulate adenylate cyclase and increase cyclic adenosine monophosphate (cAMP) levels, resulting in the transcriptional activation of target genes. The products of this gene are key mediators of neuroendocrine stress responses. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2013]
Target ID | GM-T07045 |
Target Name | PACAP-38 |
Gene ID | 116,11516,24166,100424113,607433,101090471,615187,100061356 |
Gene Symbol and Synonyms | ADCYAP1,PACAP |
Uniprot Accession | P18509,P13589,Q29W19 |
Uniprot Entry Name | PACA_HUMAN,PACA_RAT,PACA_BOVIN |
Protein Sub-location | Secreted Protein/Potential Cytokines |
Category | Therapeutics Target |
Disease | Cancer |
Gene Ensembl | ENSG00000141433 |
Target Classification | Tumor-associated antigen (TAA) |
Pre-made anti-PACAP-38 inhibitory monoclonal antibody(mab, blocking antibody inhibitor)-benchmark antibody for drug discovery and mechanism of action (MOA) research
Pre-made anti-PACAP-38 benchmark inhibitory monoclonal antibody(mab, blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). The anti-PACAP-38 mab is expressed and produced by mammalian cell line as a benchmark reference therapeutic antibody for biological drug discovery items including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Antibody Name | Species | Format | Classified by tag | Detail |
Anti-PACAP-38/ADCYAP1 monoclonal antibody | Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
Recombinant multi-species PACA/ PACAP-38/ ADCYAP1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis
Genemedi produces Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine PACAP-38/ADCYAP1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
Products Name | Species | Expression Platform | Detail |
PACAP-38/ADCYAP1 protein | Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine | Mammalian cell | Detail |
Pre-made ADCYAP1 viral vector in GM Promise-ORFTM
Cat No. | Products name | NM ID | Species | Type | Detail |
pGMLP004453 | human Adcyap1 Lentivirus plasmid | NM_001117 | Human | Lentivirus plasmid | Detail |
vGMLP004453 | human Adcyap1 Lentivirus particle | NM_001117 | Human | Lentivirus particle | Detail |
pGMAAV000317 | human ADCYAP1 AAV plasmid | NM_001099733.1 | Human | AAV plasmid | Detail |
vGMAAV000317 | human ADCYAP1 AAV particle | NM_001099733.1 | Human | AAV particle | Detail |
pGMAAV000069 | rat Adcyap1 AAV plasmid | NM_016989 | Rat | AAV plasmid | Detail |
pGMLPm001128 | mouse Adcyap1 Lentivirus plasmid | NM_001315504.1 | Mouse | Lentivirus plasmid | Detail |
vGMAAV000069 | rat Adcyap1 AAV particle | NM_016989 | Rat | AAV particle | Detail |
vGMLPm001128 | mouse Adcyap1 Lentivirus particle | NM_001315504.1 | Mouse | Lentivirus particle | Detail |
About Promise-ORFTM:
Discover the largest collection of ORF/cDNA expression clones from different species, including human, mouse, rat, and more with GeneMedi's Promise-ORFTM. Our collection of ORFs expression clones come in verified mammalian or viral vectors lentivirus, AAV, and adenovirus) and our Promise-ORFTM viral-ready expression vectors make it easy for you to improve viral vector packaging efficiency or directly transfect mammalian cells, resulting in stronger and easier expression detection. Click to search your GOI
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