ADRBK1/GRK2: Target/Biomarker Introduction, products summarized (antibody/ADC/bispecific/antigen/ORF vector/VLP) and disease/indication/condition/MOA for drug discovery and IVD
It's the GeneMedi's summary page for Target/Biomarker Introduction of ADRBK1/GRK2. The page also collects GeneMedi's different modalities and formats products for ADRBK1 in therapeutics/drug discovery and IVD diagnostics, which is including antibody, ADC, bispecific, antigen, ORF vector, VLP, etc. With GeneMedi's target-insight database-GM ITD database, the ADRBK1 target is also connected to human indications/diseases/conditions/MOA.
Target sublocation: Introcelluar Protein.
This gene encodes a member of the G protein-coupled receptor kinase family of proteins. The encoded protein phosphorylates the beta-adrenergic receptor as well as a wide range of other substrates including non-GPCR cell surface receptors, and cytoskeletal, mitochondrial, and transcription factor proteins. Data from rodent models supports a role for this gene in embryonic development, heart function and metabolism. Elevated expression of this gene has been observed in human patients with heart failure and Alzheimer's disease. [provided by RefSeq, Sep 2017]
Target ID | GM-T62548 |
Target Name | ADRBK1 |
Gene ID | 156,110355,25238,721754,483701,101101082,282682,100059001 |
Gene Symbol and Synonyms | Adrbk-1,ADRBK1,Bark-1,BARK1,beta ARK,BETA-ARK1,betaARK1,GRK-2,GRK2 |
Uniprot Accession | P25098,P26817,P21146 |
Uniprot Entry Name | ARBK1_HUMAN,ARBK1_RAT,ARBK1_BOVIN |
Protein Sub-location | Introcelluar Protein |
Category | Therapeutics Target |
Disease | N/A |
Gene Ensembl | ENSG00000173020 |
Target Classification | Kinase |
Pre-made anti-ADRBK1 inhibitory monoclonal antibody(mab, blocking antibody inhibitor)-benchmark antibody for drug discovery and mechanism of action (MOA) research
Pre-made anti-ADRBK1 monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). The anti-ADRBK1 mab is expressed and produced by mammalian cell line as a benchmark reference therapeutic antibody for biological drug discovery items including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Antibody Name | Species | Format | Classified by tag | Detail |
Anti-ADRBK1/GRK2 monoclonal antibody | Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine | mab | Therapeutics Target antibody | Detail |
Recombinant multi-species ARBK1/ ADRBK1/ GRK2 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis
Genemedi produces Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine ADRBK1/GRK2 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
Products Name | Species | Expression Platform | Detail |
ADRBK1/GRK2 protein | Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine | Mammalian cell | Detail |
Pre-made GRK2 viral vector in GM Promise-ORFTM
Cat No. | Products name | NM ID | Species | Type | Detail |
pGMLP001657 | human GRK2 Lentivirus plasmid | NM_001619 | Human | Lentivirus plasmid | Detail |
vGMLV000648 | human GRK2 Lentivirus particle | NM_001619.4 | Human | Lentivirus particle | Detail |
vGMLP001657 | human GRK2 Lentivirus particle | NM_001619 | Human | Lentivirus particle | Detail |
pGMLV000648 | human GRK2 Lentivirus plasmid | NM_001619.4 | Human | Lentivirus plasmid | Detail |
pGMAD000099 | pig GRK2 Adenovirus plasmid | NM_001244878.1 | Pig | Adenovirus plasmid | Detail |
pGMAAV000240 | Norway rat Grk2 AAV plasmid | NM_012776.1 | Norway Rat | AAV plasmid | Detail |
vGMAD000099 | pig GRK2 Adenovirus particle | NM_001244878.1 | Pig | Adenovirus particle | Detail |
vGMAAV000240 | Norway rat Grk2 AAV particle | NM_012776.1 | Norway Rat | AAV particle | Detail |
About Promise-ORFTM:
Discover the largest collection of ORF/cDNA expression clones from different species, including human, mouse, rat, and more with GeneMedi's Promise-ORFTM. Our collection of ORFs expression clones come in verified mammalian or viral vectors lentivirus, AAV, and adenovirus) and our Promise-ORFTM viral-ready expression vectors make it easy for you to improve viral vector packaging efficiency or directly transfect mammalian cells, resulting in stronger and easier expression detection. Click to search your GOI
If you want to obtain higher quantities of plasmids (mg), please visit GM TransExcellent Plasmid DNA Rapid Preparation Service.