ADRBK1/GRK2: Target/Biomarker Introduction, products summarized (antibody/ADC/bispecific/antigen/ORF vector/VLP) and disease/indication/condition/MOA for drug discovery and IVD

It's the GeneMedi's summary page for Target/Biomarker Introduction of ADRBK1/GRK2. The page also collects GeneMedi's different modalities and formats products for ADRBK1 in therapeutics/drug discovery and IVD diagnostics, which is including antibody, ADC, bispecific, antigen, ORF vector, VLP, etc. With GeneMedi's target-insight database-GM ITD database, the ADRBK1 target is also connected to human indications/diseases/conditions/MOA.

Target sublocation: Introcelluar Protein.

This gene encodes a member of the G protein-coupled receptor kinase family of proteins. The encoded protein phosphorylates the beta-adrenergic receptor as well as a wide range of other substrates including non-GPCR cell surface receptors, and cytoskeletal, mitochondrial, and transcription factor proteins. Data from rodent models supports a role for this gene in embryonic development, heart function and metabolism. Elevated expression of this gene has been observed in human patients with heart failure and Alzheimer's disease. [provided by RefSeq, Sep 2017]

Target IDGM-T62548
Target NameADRBK1
Gene ID156,110355,25238,721754,483701,101101082,282682,100059001
Gene Symbol and SynonymsAdrbk-1,ADRBK1,Bark-1,BARK1,beta ARK,BETA-ARK1,betaARK1,GRK-2,GRK2
Uniprot AccessionP25098,P26817,P21146
Uniprot Entry NameARBK1_HUMAN,ARBK1_RAT,ARBK1_BOVIN
Protein Sub-locationIntrocelluar Protein
CategoryTherapeutics Target
DiseaseN/A
Gene EnsemblENSG00000173020
Target ClassificationKinase


Pre-made anti-ADRBK1 inhibitory monoclonal antibody(mab, blocking antibody inhibitor)-benchmark antibody for drug discovery and mechanism of action (MOA) research

Pre-made anti-ADRBK1 monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). The anti-ADRBK1 mab is expressed and produced by mammalian cell line as a benchmark reference therapeutic antibody for biological drug discovery items including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.

Antibody NameSpeciesFormatClassified by tagDetail
Anti-ADRBK1/GRK2 monoclonal antibodyHuman, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, EquinemabTherapeutics Target antibodyDetail



Recombinant multi-species ARBK1/ ADRBK1/ GRK2 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine ADRBK1/GRK2 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.

Products NameSpeciesExpression PlatformDetail
ADRBK1/GRK2 proteinHuman, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, EquineMammalian cellDetail



Pre-made GRK2 viral vector in GM Promise-ORFTM

Cat No.Products nameNM IDSpeciesTypeDetail
pGMLP001657human GRK2 Lentivirus plasmidNM_001619HumanLentivirus plasmidDetail
vGMLV000648human GRK2 Lentivirus particleNM_001619.4HumanLentivirus particleDetail
vGMLP001657human GRK2 Lentivirus particleNM_001619HumanLentivirus particleDetail
pGMLV000648human GRK2 Lentivirus plasmidNM_001619.4HumanLentivirus plasmidDetail
pGMAD000099pig GRK2 Adenovirus plasmidNM_001244878.1PigAdenovirus plasmidDetail
pGMAAV000240Norway rat Grk2 AAV plasmidNM_012776.1Norway RatAAV plasmidDetail
vGMAD000099pig GRK2 Adenovirus particleNM_001244878.1PigAdenovirus particleDetail
vGMAAV000240Norway rat Grk2 AAV particleNM_012776.1Norway RatAAV particleDetail

About Promise-ORFTM:
Discover the largest collection of ORF/cDNA expression clones from different species, including human, mouse, rat, and more with GeneMedi's Promise-ORFTM. Our collection of ORFs expression clones come in verified mammalian or viral vectors lentivirus, AAV, and adenovirus) and our Promise-ORFTM viral-ready expression vectors make it easy for you to improve viral vector packaging efficiency or directly transfect mammalian cells, resulting in stronger and easier expression detection. Click to search your GOI

If you want to obtain higher quantities of plasmids (mg), please visit GM TransExcellent Plasmid DNA Rapid Preparation Service.






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