Rat Grk2/Adrbk1/ BARK1 ORF/cDNA clone-Adeno-associate virus(AAV) plasmid (NM_012776.1)
Pre-made Rat Grk2/Adrbk1/ BARK1 Adeno-associated virus expression plasmid (ITR-vector) for Grk2 AAV packaging, Grk2 AAV production.The purified Rat Grk2/Adrbk1/ BARK1 AAV particle serves as an invaluable asset for in-depth in vivo Grk2 studies, mechanism of action (MOA) research, and the evolution of Grk2-associated gene therapy strategies.
Our GM-AAV ITR vector is optimized with the G-NEXT™ multi-serotypes AAV vector system. Explore the G-NEXT™ system in detail.
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Product information
Catalog No. | Product Name | Plasmid Grade | Plasmid quantity |
---|---|---|---|
pGMAAV000240 | Rat Grk2 Adeno-associate virus(AAV) plasmid | Research Grade | 10mg, 50mg, 100mg, 500mg, >1g |
GMP-like Grade | 10mg, 50mg, 100mg, 500mg, >1g | ||
High Quality (HQ) Grade | |||
Seed | 5ug |
Product Description
Catalog ID | pGMAAV000240 |
Gene Name | Grk2 |
Accession Number | NM_012776.1 |
Gene ID | 25238 |
Species | Rat |
Product Type | Adeno-associate virus(AAV) plasmid (overexpression) |
Insert Length | 2070 bp |
Gene Alias | Adrbk1, BARK1, GRK-2 |
Fluorescent Reporter | |
Mammalian Cell Selection | Null |
Fusion Tag | 3xflag (C-Terminal) |
Promoter | CMV |
Resistance | Amplicin |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
Category | Cat No. | Products Name |
---|---|---|
Target Antibody | GM-Tg-g-T62548-Ab | Anti-ADRBK1 monoclonal antibody |
Target Antigen | GM-Tg-g-T62548-Ag | ADRBK1/GRK2 protein |
ORF Viral Vector | pGMLV000648 | Human GRK2 Lentivirus plasmid |
ORF Viral Vector | pGMAAV000240 | Rat Grk2 Adeno-associate virus(AAV) plasmid |
ORF Viral Vector | pGMPC000105 | Rat Grk2 Mammalian (Non-Viral Vector) plasmid |
ORF Viral Vector | pGMPC000338 | Rat Grk2 Mammalian (Non-Viral Vector) plasmid |
ORF Viral Vector | pGMLP001657 | Human GRK2 Lentivirus plasmid |
ORF Viral Vector | vGMLV000648 | Human GRK2 Lentivirus particle |
ORF Viral Vector | vGMAAV000240 | Rat Grk2 Adeno-associate virus(AAV) particle |
ORF Viral Vector | vGMLP001657 | Human GRK2 Lentivirus particle |
Target information
Target ID | GM-T62548 |
Target Name | ADRBK1 |
Gene ID | 156, 110355, 721754, 25238, 101101082, 483701, 282682, 100059001 |
Gene Symbol and Synonyms | Adrbk-1,ADRBK1,Bark-1,BARK1,beta ARK,BETA-ARK1,betaARK1,GRK-2,GRK2 |
Uniprot Accession | P25098 |
Uniprot Entry Name | ARBK1_HUMAN |
Protein Sub-location | Introcelluar Protein |
Category | Therapeutics Target |
Disease | Not Available |
Gene Ensembl | ENSG00000173020 |
Target Classification | Kinase |
This gene encodes a member of the G protein-coupled receptor kinase family of proteins. The encoded protein phosphorylates the beta-adrenergic receptor as well as a wide range of other substrates including non-GPCR cell surface receptors, and cytoskeletal, mitochondrial, and transcription factor proteins. Data from rodent models supports a role for this gene in embryonic development, heart function and metabolism. Elevated expression of this gene has been observed in human patients with heart failure and Alzheimer's disease. [provided by RefSeq, Sep 2017]
About GMVC
GMVC (GM Vector Core) is GeneMedi’s unique platform for QbD Viral vectors Processes development and manufacturing. In GMVC, our core expertise lies in the tailored production of viral vectors, including adeno-associated virus (AAV), lentivirus, and adenovirus. Our state-of-the-art facilities are equipped for scalable manufacturing, ensuring high-quality viral vector production to meet both research and therapeutic needs. Our expert team specializes in process development, leveraging innovative technology and extensive industry knowledge to provide clients with tailored solutions that exceed expectations. GMVC will be the ideal partner for scientists and healthcare professionals seeking reliable and efficient viral vector production services.