Rat Grk2/Adrbk1/ BARK1 ORF/cDNA clone-Adeno-associate virus(AAV) plasmid (NM_012776.1)

Pre-made Rat Grk2/Adrbk1/ BARK1 Adeno-associated virus expression plasmid (ITR-vector) for Grk2 AAV packaging, Grk2 AAV production.The purified Rat Grk2/Adrbk1/ BARK1 AAV particle serves as an invaluable asset for in-depth in vivo Grk2 studies, mechanism of action (MOA) research, and the evolution of Grk2-associated gene therapy strategies.

Our GM-AAV ITR vector is optimized with the G-NEXT™ multi-serotypes AAV vector system. Explore the G-NEXT™ system in detail.

Target products collectionGo to ADRBK1/Grk2/Adrbk1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)



Product information

Catalog No. Product Name Plasmid Grade Plasmid quantity
pGMAAV000240 Rat Grk2 Adeno-associate virus(AAV) plasmid Research Grade 10mg, 50mg, 100mg, 500mg, >1g
GMP-like Grade 10mg, 50mg, 100mg, 500mg, >1g
High Quality (HQ) Grade
Seed 5ug


Product Description

Catalog ID pGMAAV000240
Gene Name Grk2
Accession Number NM_012776.1
Gene ID 25238
Species Rat
Product Type Adeno-associate virus(AAV) plasmid (overexpression)
Insert Length 2070 bp
Gene Alias Adrbk1, BARK1, GRK-2
Fluorescent Reporter
Mammalian Cell Selection Null
Fusion Tag 3xflag (C-Terminal)
Promoter CMV
Resistance Amplicin

Reference




    Data / case study


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    Associated products


    Category Cat No. Products Name
    Target Antibody GM-Tg-g-T62548-Ab Anti-ADRBK1 monoclonal antibody
    Target Antigen GM-Tg-g-T62548-Ag ADRBK1/GRK2 protein
    ORF Viral Vector pGMLV000648 Human GRK2 Lentivirus plasmid
    ORF Viral Vector pGMAAV000240 Rat Grk2 Adeno-associate virus(AAV) plasmid
    ORF Viral Vector pGMPC000105 Rat Grk2 Mammalian (Non-Viral Vector) plasmid
    ORF Viral Vector pGMPC000338 Rat Grk2 Mammalian (Non-Viral Vector) plasmid
    ORF Viral Vector pGMLP001657 Human GRK2 Lentivirus plasmid
    ORF Viral Vector vGMLV000648 Human GRK2 Lentivirus particle
    ORF Viral Vector vGMAAV000240 Rat Grk2 Adeno-associate virus(AAV) particle
    ORF Viral Vector vGMLP001657 Human GRK2 Lentivirus particle


    Target information

    Target ID GM-T62548
    Target Name ADRBK1
    Gene ID 156, 110355, 721754, 25238, 101101082, 483701, 282682, 100059001
    Gene Symbol and Synonyms Adrbk-1,ADRBK1,Bark-1,BARK1,beta ARK,BETA-ARK1,betaARK1,GRK-2,GRK2
    Uniprot Accession P25098
    Uniprot Entry Name ARBK1_HUMAN
    Protein Sub-location Introcelluar Protein
    Category Therapeutics Target
    Disease Not Available
    Gene Ensembl ENSG00000173020
    Target Classification Kinase

    This gene encodes a member of the G protein-coupled receptor kinase family of proteins. The encoded protein phosphorylates the beta-adrenergic receptor as well as a wide range of other substrates including non-GPCR cell surface receptors, and cytoskeletal, mitochondrial, and transcription factor proteins. Data from rodent models supports a role for this gene in embryonic development, heart function and metabolism. Elevated expression of this gene has been observed in human patients with heart failure and Alzheimer's disease. [provided by RefSeq, Sep 2017]



    About GMVC

    GDU



    GMVC (GM Vector Core) is GeneMedi’s unique platform for QbD Viral vectors Processes development and manufacturing. In GMVC, our core expertise lies in the tailored production of viral vectors, including adeno-associated virus (AAV), lentivirus, and adenovirus. Our state-of-the-art facilities are equipped for scalable manufacturing, ensuring high-quality viral vector production to meet both research and therapeutic needs. Our expert team specializes in process development, leveraging innovative technology and extensive industry knowledge to provide clients with tailored solutions that exceed expectations. GMVC will be the ideal partner for scientists and healthcare professionals seeking reliable and efficient viral vector production services.