Rat Grk2/Adrbk1/ BARK1 ORF/cDNA clone-Adeno-associate virus(AAV) particle (NM_012776.1)
Pre-made Rat Grk2/Adrbk1/ BARK1 Adeno-associated virus particle for Grk2 in-vivo study, mechanism of action (MOA) research and Grk2-associated gene therapy development.
At GM Vector Core (GMVC), we stand at the forefront of custom AAV development and produce distinct grades of AAVs employing state-of-the-art methodologies. Uncover more about our expertise.
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Product information
Catalog No. | Product Name | AAV serotype | AAV Grade | AAV quantity |
vGMAAV000240 | Rat Grk2 Adeno-associate virus(AAV) particle | AAV1, AAV2, AAV2 variant (Y444F), AAV2 variant (Y272F, Y444F, Y500F, Y730F), AAV2 variant (Y444F, Y730F, Y500F, Y272F, Y704F, Y252F), AAV2 variant(AAV2.7m8), AAV5, AAV6, AAV8, AAV8-1m, AAV8-2m, AAV8 variant (Y733F, Y447F, Y275), AAV9, AAV-Rh.10, AAV-DJ, AAV-DJ/8, AAV-Retro (Retrograde), AAV9-PHP.B, AAV9-PHP.eB, AAV9-PHP.S, AAV-BR1, AAV-2i8, AAV-SIG, AAV-VEC, AAV4, AAV6.2, AAV6.2FF | Pilot Grade | 1.0E+12VG/ml |
5.0E+12VG/ml | ||||
1E+13VG/ml | ||||
5E+13VG/ml | ||||
1E+14VG/ml | ||||
Research Grade | 1.0E+12VG/ml | |||
5.0E+12VG/ml | ||||
1E+13VG/ml | ||||
5E+13VG/ml | ||||
1E+14VG/ml | ||||
GMP-like Grade | inquiry | |||
GMP Grade | inquiry |
Product Description
Catalog ID | vGMAAV000240 |
Gene Name | Grk2 |
Accession Number | NM_012776.1 |
Gene ID | 25238 |
Species | Rat |
Product Type | Adeno-associate virus(AAV) particle (overexpression) |
Insert Length | 2070 bp |
Gene Alias | Adrbk1, BARK1, GRK-2 |
Fluorescent Reporter | |
Mammalian Cell Selection | Null |
Fusion Tag | 3xflag (C-Terminal) |
Promoter | CMV |
Resistance | Amplicin |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
Category | Cat No. | Products Name |
---|---|---|
Target Antibody | GM-Tg-g-T62548-Ab | Anti-ADRBK1 monoclonal antibody |
Target Antigen | GM-Tg-g-T62548-Ag | ADRBK1/GRK2 protein |
ORF Viral Vector | pGMLV000648 | Human GRK2 Lentivirus plasmid |
ORF Viral Vector | pGMAAV000240 | Rat Grk2 Adeno-associate virus(AAV) plasmid |
ORF Viral Vector | pGMPC000105 | Rat Grk2 Mammalian (Non-Viral Vector) plasmid |
ORF Viral Vector | pGMPC000338 | Rat Grk2 Mammalian (Non-Viral Vector) plasmid |
ORF Viral Vector | pGMLP001657 | Human GRK2 Lentivirus plasmid |
ORF Viral Vector | vGMLV000648 | Human GRK2 Lentivirus particle |
ORF Viral Vector | vGMAAV000240 | Rat Grk2 Adeno-associate virus(AAV) particle |
ORF Viral Vector | vGMLP001657 | Human GRK2 Lentivirus particle |
Target information
Target ID | GM-T62548 |
Target Name | ADRBK1 |
Gene ID | 156, 110355, 721754, 25238, 101101082, 483701, 282682, 100059001 |
Gene Symbol and Synonyms | Adrbk-1,ADRBK1,Bark-1,BARK1,beta ARK,BETA-ARK1,betaARK1,GRK-2,GRK2 |
Uniprot Accession | P25098 |
Uniprot Entry Name | ARBK1_HUMAN |
Protein Sub-location | Introcelluar Protein |
Category | Therapeutics Target |
Disease | Not Available |
Gene Ensembl | ENSG00000173020 |
Target Classification | Kinase |
This gene encodes a member of the G protein-coupled receptor kinase family of proteins. The encoded protein phosphorylates the beta-adrenergic receptor as well as a wide range of other substrates including non-GPCR cell surface receptors, and cytoskeletal, mitochondrial, and transcription factor proteins. Data from rodent models supports a role for this gene in embryonic development, heart function and metabolism. Elevated expression of this gene has been observed in human patients with heart failure and Alzheimer's disease. [provided by RefSeq, Sep 2017]
About GMVC
GMVC (GM Vector Core) is GeneMedi’s unique platform for QbD Viral vectors Processes development and manufacturing. In GMVC, our core expertise lies in the tailored production of viral vectors, including adeno-associated virus (AAV), lentivirus, and adenovirus. Our state-of-the-art facilities are equipped for scalable manufacturing, ensuring high-quality viral vector production to meet both research and therapeutic needs. Our expert team specializes in process development, leveraging innovative technology and extensive industry knowledge to provide clients with tailored solutions that exceed expectations. GMVC will be the ideal partner for scientists and healthcare professionals seeking reliable and efficient viral vector production services.