Bovine relaxin antibody and antigen (recombinant protein)

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Diagnostic anti-Bovine relaxin antibodies pairs and antigen for animal health (animal Bovines/Cattle Pregnancy) testing in ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA and POCT

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Size： 1mg | 10mg | 100mg

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Target/Biomarker Information

Relaxin, a multifaceted peptide hormone, takes center stage in the intricate drama of reproductive physiology and tissue remodeling in mammals, including humans and dogs. This remarkable hormone, a member of the insulin/relaxin superfamily, stands as a testament to the intricate interplay of molecular signals governing pivotal life processes.

Structurally, relaxin is characterized by its complex chain of amino acids, and its synthesis primarily occurs in the corpus luteum during pregnancy. This temporary endocrine gland within the ovaries emerges post-ovulation and serves as the primary source of relaxin production.

In the context of pregnancy, relaxin orchestrates a symphony of physiological changes to ensure the successful progression of gestation. Among its primary roles is the promotion of uterine relaxation. By relaxing the smooth muscles of the uterus, relaxin prevents premature contractions, providing a safe environment for the developing fetus. This uterine relaxation also facilitates the dilation of the cervix during labor, allowing for the passage of the newborn.

Beyond its impact on uterine and cervical physiology, relaxin extends its reach to the cardiovascular system. During pregnancy, it plays a crucial role in vasodilation, leading to the expansion of blood vessels. This adaptive response ensures increased blood flow to the uterus and placenta, facilitating the exchange of vital nutrients and oxygen between the mother and the developing embryo. It is this finely orchestrated vascular dance that supports the nourishment and growth of the fetus.

Interestingly, relaxin's influence isn't confined to pregnancy alone. It also plays a role in tissue remodeling, affecting processes such as wound healing and collagen metabolism. In these contexts, relaxin promotes the breakdown of collagen, the principal structural protein in connective tissues. This effect can be particularly relevant in the management of conditions involving fibrosis or scar tissue formation.

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