Canine Pregnancy-associated glycoprotein 1 antibody and antigen (recombinant protein)

 Download 

Diagnostic anti-Canine Pregnancy-associated glycoprotein 1 antibodies pairs and antigen for animal health (animal Dog/Canine) testing in ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA and POCT

Go to Companion Animal disease testing products collection >>

Product information

Size： 1mg | 10mg | 100mg

Product Description

Reference

Validation Data

Click to get more Data / Case study about the product.

Target/Biomarker Information

As of my last update in April 2023, the specific study or application of Pregnancy-associated glycoprotein 1 (PAG1) in dogs (canines) for pregnancy diagnosis or monitoring is not broadly documented in veterinary practice or literature. The concept of pregnancy-associated glycoproteins (PAGs) has been extensively explored in ruminants, like cattle and sheep, where PAGs are recognized as reliable markers of pregnancy and are used for early detection and monitoring purposes. PAGs are produced by the placenta and serve various functions, including supporting the maternal recognition of pregnancy and modulating the maternal immune system to favor pregnancy maintenance.

In canine pregnancy diagnosis and monitoring, the focus tends to be on other methods and markers:

Relaxin Hormone Assays: Relaxin, a hormone produced by the placenta, is a key biomarker for confirming pregnancy in dogs. Commercially available relaxin tests can detect pregnancy as early as 22-30 days post-breeding. Relaxin levels remain elevated throughout pregnancy, making it a reliable indicator.

Ultrasound: Ultrasound is a primary diagnostic tool used to confirm pregnancy in dogs, typically starting around 25-30 days post-breeding. It allows for visualization of the gestational sacs, developing fetuses, and assessment of fetal health.

Radiography (X-rays): X-rays are useful later in pregnancy (usually after 45 days post-breeding) for counting the number of fetuses and assessing skeletal development. This method helps in preparing for whelping but is not suitable for early pregnancy diagnosis.

Physical Examination and Palpation: Veterinary practitioners may use physical examination and palpation techniques to suggest pregnancy, particularly in the mid to late stages. However, these methods are less definitive without the support of imaging or hormonal assays.

Progesterone Levels: Monitoring progesterone levels is useful around the time of breeding to confirm ovulation and optimal mating times but not for diagnosing pregnancy itself.

While PAGs play significant roles in the pregnancies of other mammals, especially in species like cattle, their study, identification, and application in canine pregnancy remain limited in scope. Research in veterinary medicine continues to evolve, and future discoveries may expand the toolkit for pregnancy diagnosis and monitoring in dogs, potentially including markers like PAG1 if their relevance to canine pregnancy is established and validated.

For the most accurate and up-to-date information on canine pregnancy diagnosis and the potential role of PAGs or other emerging biomarkers, consultation with veterinary reproductive specialists and review of current veterinary literature are recommended.

About GDU