Feline Pregnancy-associated glycoprotein 1 antibody and antigen (recombinant protein)

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Diagnostic anti-Feline Pregnancy-associated glycoprotein 1 antibodies pairs and antigen for animal health (animal Cat/Feline) testing in ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA and POCT

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Reference

Validation Data

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Target/Biomarker Information

As of my last update in April 2023, there is limited specific information on "Pregnancy-associated glycoprotein 1" (PAG1) in cats (felines) in the context of pregnancy diagnosis or monitoring. In veterinary medicine and reproductive biology, the study of pregnancy-associated glycoproteins (PAGs) has been more extensively conducted in cattle, sheep, and goats, where PAGs serve as important markers for early pregnancy detection and monitoring fetal well-being.

PAGs are a family of proteins produced by the placental trophoblast cells, and their presence in the blood or milk of pregnant animals has been used as a reliable indicator of pregnancy. These proteins play roles in supporting pregnancy, including immunosuppression at the maternal-fetal interface, to ensure successful pregnancy maintenance.

In cats, the primary methods for pregnancy diagnosis include:

Physical Examination: Changes in body condition, mammary gland development, and behavior may suggest pregnancy but are not definitive without further testing.

Ultrasound: Ultrasound examination can confirm pregnancy by visualizing the developing embryos, typically around 15 to 20 days after conception. It is a non-invasive method and allows for early detection of pregnancy and assessment of fetal health.

Hormone Assays: The hormone relaxin, produced by the developing placenta, can be measured in the blood serum of pregnant cats. Relaxin assays are available and can accurately diagnose pregnancy from around 25 to 30 days post-conception.

Radiography (X-rays): Later in pregnancy (typically after 45 days), radiography can confirm pregnancy by visualizing the skeletal structures of the fetuses. This method is also used to estimate litter size but is not suitable for early pregnancy diagnosis.

While PAGs have been a focus of research in other species for pregnancy-related studies, the application and research into PAGs, including Pregnancy-associated glycoprotein 1 in cats, are not widely documented or used in clinical practice for feline pregnancy diagnosis. The field of veterinary reproductive biology continues to evolve, and future research may expand the understanding and diagnostic tools available for pregnancy detection and monitoring across different species, including cats. For the most current and specific information, consulting recent scientific literature or veterinary reproductive specialists is recommended.

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