NTF3: Target/Biomarker Introduction, products summarized (antibody/ADC/bispecific/antigen/ORF vector/VLP) and disease/indication/condition/MOA for drug discovery and IVD
It's the GeneMedi's summary page for Target/Biomarker Introduction of NTF3. The page also collects GeneMedi's different modalities and formats products for NTF3 in therapeutics/drug discovery and IVD diagnostics, which is including antibody, ADC, bispecific, antigen, ORF vector, VLP, etc. With GeneMedi's target-insight database-GM ITD database, the NTF3 target is also connected to human indications/diseases/conditions/MOA.
Target sublocation: Secreted Protein/Potential Cytokines.
The protein encoded by this gene is a member of the neurotrophin family, that controls survival and differentiation of mammalian neurons. This protein is closely related to both nerve growth factor and brain-derived neurotrophic factor. It may be involved in the maintenance of the adult nervous system, and may affect development of neurons in the embryo when it is expressed in human placenta. NTF3-deficient mice generated by gene targeting display severe movement defects of the limbs. The mature peptide of this protein is identical in all mammals examined including human, pig, rat and mouse. [provided by RefSeq, Jul 2008]
Target ID | GM-T32855 |
Target Name | NTF3 |
Gene ID | 4908,18205,81737,721988,486731,493963,532393,100051839 |
Gene Symbol and Synonyms | HDNF,NGF-2,NGF2,NT-3,NT3,Ntf-3,NTF3 |
Uniprot Accession | P20783,P18280,Q9TST2,Q08DT3 |
Uniprot Entry Name | NTF3_HUMAN,NTF3_RAT,NTF3_FELCA,NTF3_BOVIN |
Protein Sub-location | Secreted Protein/Potential Cytokines |
Category | Therapeutics Target |
Disease | Schizophrenia |
Gene Ensembl | ENSG00000185652 |
Target Classification | N/A |
Pre-made anti-NTF3 inhibitory monoclonal antibody(mab, blocking antibody inhibitor)-benchmark antibody for drug discovery and mechanism of action (MOA) research
Pre-made anti-NTF3 benchmark inhibitory monoclonal antibody(mab, blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). The anti-NTF3 mab is expressed and produced by mammalian cell line as a benchmark reference therapeutic antibody for biological drug discovery items including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Antibody Name | Species | Format | Classified by tag | Detail |
Anti-NTF3 monoclonal antibody | Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
Recombinant multi-species NTF3/ HDNF/ NGF-2 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis
Genemedi produces Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine NTF3 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
Products Name | Species | Expression Platform | Detail |
NTF3 protein | Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine | Mammalian cell | Detail |
Pre-made NTF3 viral vector in GM Promise-ORFTM
Cat No. | Products name | NM ID | Species | Type | Detail |
pGMAP000383 | Human NTF3 Adenovirus plasmid | BC069773 | Human | Adenovirus plasmid | Detail |
vGMAD000046 | human NTF3 Adenovirus particle | NM_001102654 | Human | Adenovirus particle | Detail |
vGMAP000383 | Human NTF3 Adenovirus particle | BC069773 | Human | Adenovirus particle | Detail |
pGMAD000046 | human NTF3 Adenovirus plasmid | NM_001102654 | Human | Adenovirus plasmid | Detail |
pGMLPm001258 | mouse Ntf3 Lentivirus plasmid | NM_031073 | Mouse | Lentivirus plasmid | Detail |
pGMLPm001588 | mouse Ntf3 Lentivirus plasmid | NM_001164034 | Mouse | Lentivirus plasmid | Detail |
vGMLPm001258 | mouse Ntf3 Lentivirus particle | NM_031073 | Mouse | Lentivirus particle | Detail |
vGMLPm001588 | mouse Ntf3 Lentivirus particle | NM_001164034 | Mouse | Lentivirus particle | Detail |
About Promise-ORFTM:
Discover the largest collection of ORF/cDNA expression clones from different species, including human, mouse, rat, and more with GeneMedi's Promise-ORFTM. Our collection of ORFs expression clones come in verified mammalian or viral vectors lentivirus, AAV, and adenovirus) and our Promise-ORFTM viral-ready expression vectors make it easy for you to improve viral vector packaging efficiency or directly transfect mammalian cells, resulting in stronger and easier expression detection. Click to search your GOI
If you want to obtain higher quantities of plasmids (mg), please visit GM TransExcellent Plasmid DNA Rapid Preparation Service.