- • Up to 20% off your first purchase
- • Bulk quantities available
- • Citation Reward application
Sample Application
- Animal health test
- In-vitro diagnostics
- Food & Feed Safety
- Environmental Safety
- New drug discovery
Supports
- Talk to our Expert:
[email protected] -
Talk to our sales:
[email protected]
Protocol Library Download
 |
 |
Anti-NTF3/ HDNF/ NGF-2 functional antibody
Anti-NTF3/ HDNF/ NGF-2 functional antibody for cell culture, ELISA & in-vivo assay
Go to NTF3/NTF3 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-T32855-Ab-1/ GM-Tg-hg-T32855-Ab-2 | Anti-Human NTF3 monoclonal antibody | Human |
| GM-Tg-rg-T32855-Ab-1/ GM-Tg-rg-T32855-Ab-2 | Anti-Rat NTF3 monoclonal antibody | Rat |
| GM-Tg-mg-T32855-Ab-1/ GM-Tg-mg-T32855-Ab-2 | Anti-Mouse NTF3 monoclonal antibody | Mouse |
| GM-Tg-cynog-T32855-Ab-1/ GM-Tg-cynog-T32855-Ab-2 | Anti-Cynomolgus/ Rhesus macaque NTF3 monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-T32855-Ab-1/ GM-Tg-felg-T32855-Ab-2 | Anti-Feline NTF3 monoclonal antibody | Feline |
| GM-Tg-cang-T32855-Ab-1/ GM-Tg-cang-T32855-Ab-2 | Anti-Canine NTF3 monoclonal antibody | Canine |
| GM-Tg-bovg-T32855-Ab-1/ GM-Tg-bovg-T32855-Ab-2 | Anti-Bovine NTF3 monoclonal antibody | Bovine |
| GM-Tg-equg-T32855-Ab-1/ GM-Tg-equg-T32855-Ab-2 | Anti-Equine NTF3 monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-T32855-Ab-1/ GM-Tg-hg-T32855-Ab-2; GM-Tg-rg-T32855-Ab-1/ GM-Tg-rg-T32855-Ab-2; GM-Tg-mg-T32855-Ab-1/ GM-Tg-mg-T32855-Ab-2; GM-Tg-cynog-T32855-Ab-1/ GM-Tg-cynog-T32855-Ab-2; GM-Tg-felg-T32855-Ab-1/ GM-Tg-felg-T32855-Ab-2; GM-Tg-cang-T32855-Ab-1/ GM-Tg-cang-T32855-Ab-2; GM-Tg-bovg-T32855-Ab-1/ GM-Tg-bovg-T32855-Ab-2; GM-Tg-equg-T32855-Ab-1/ GM-Tg-equg-T32855-Ab-2 |
| Products Name | Anti-NTF3 monoclonal antibody |
| Format | mab |
| Target Name | NTF3 |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Category of antibody | FACS/Biofunctional Antibody, Therapeutics Target antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD). |
| Tag | Fc |
| Products description | Pre-made anti-NTF3 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation | Lyophilized from sterile PBS, PH 7.4 |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | GM-Tg-g-T32855-Ag-1 | Recombinant multi-species NTF3/ HDNF/ NGF-2 protein |
| ORF Viral Vector | pGMAP000383 | Human NTF3 Adenovirus plasmid |
| ORF Viral Vector | vGMAD000046 | human NTF3 Adenovirus particle |
| ORF Viral Vector | vGMAP000383 | Human NTF3 Adenovirus particle |
| ORF Viral Vector | pGMAD000046 | human NTF3 Adenovirus plasmid |
| ORF Viral Vector | pGMLPm001258 | mouse Ntf3 Lentivirus plasmid |
| ORF Viral Vector | pGMLPm001588 | mouse Ntf3 Lentivirus plasmid |
| ORF Viral Vector | vGMLPm001258 | mouse Ntf3 Lentivirus particle |
| ORF Viral Vector | vGMLPm001588 | mouse Ntf3 Lentivirus particle |
Target information
| Target ID | GM-T32855 |
| Target Name | NTF3 |
| Gene ID | 4908,18205,81737,721988,486731,493963,532393,100051839 |
| Gene Symbol and Synonyms | HDNF,NGF-2,NGF2,NT-3,NT3,Ntf-3,NTF3 |
| Uniprot Accession | P20783,P18280,Q9TST2,Q08DT3 |
| Uniprot Entry Name | NTF3_HUMAN,NTF3_RAT,NTF3_FELCA,NTF3_BOVIN |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Category | Therapeutics Target |
| Disease | Schizophrenia |
| Gene Ensembl | ENSG00000185652 |
| Target Classification | N/A |
The target: NTF3, gene name: NTF3, also named as HDNF, NGF-2, NGF2, NT-3, NT3. The protein encoded by this gene is a member of the neurotrophin family, that controls survival and differentiation of mammalian neurons. This protein is closely related to both nerve growth factor and brain-derived neurotrophic factor. It may be involved in the maintenance of the adult nervous system, and may affect development of neurons in the embryo when it is expressed in human placenta. NTF3-deficient mice generated by gene targeting display severe movement defects of the limbs. The mature peptide of this protein is identical in all mammals examined including human, pig, rat and mouse. [provided by RefSeq, Jul 2008].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
Facebook
LinkedIn
Twitter
