EZH2: Target/Biomarker Introduction, products summarized (antibody/ADC/bispecific/antigen/ORF vector/VLP) and disease/indication/condition/MOA for drug discovery and IVD
It's the GeneMedi's summary page for Target/Biomarker Introduction of EZH2. The page also collects GeneMedi's different modalities and formats products for EZH2 in therapeutics/drug discovery and IVD diagnostics, which is including antibody, ADC, bispecific, antigen, ORF vector, VLP, etc. With GeneMedi's target-insight database-GM ITD database, the EZH2 target is also connected to human indications/diseases/conditions/MOA.
Target sublocation: Introcelluar Protein.
This gene encodes a member of the Polycomb-group (PcG) family. PcG family members form multimeric protein complexes, which are involved in maintaining the transcriptional repressive state of genes over successive cell generations. This protein associates with the embryonic ectoderm development protein, the VAV1 oncoprotein, and the X-linked nuclear protein. This protein may play a role in the hematopoietic and central nervous systems. Multiple alternatively splcied transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Feb 2011]
|Gene Symbol and Synonyms||ENX-1,ENX1,Enx1h,EZH2,EZH2b,KMT6,KMT6A,mKIAA4065,WVS,WVS2|
|Uniprot Entry Name||EZH2_HUMAN|
|Protein Sub-location||Introcelluar Protein|
|Target Classification||Tumor-associated antigen (TAA)|
Pre-made anti-EZH2 inhibitory monoclonal antibody(mab, blocking antibody inhibitor)-benchmark antibody for drug discovery and mechanism of action (MOA) research
Pre-made anti-EZH2 monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). The anti-EZH2 mab is expressed and produced by mammalian cell line as a benchmark reference therapeutic antibody for biological drug discovery items including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
|Antibody Name||Species||Format||Classified by tag||Detail|
|Anti-EZH2 monoclonal antibody||Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine||mab||Therapeutics Target antibody||Detail|
Recombinant multi-species EZH2/ ENX-1/ ENX1b protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis
Genemedi produces Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine EZH2 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
|Products Name||Species||Expression Platform||Detail|
|EZH2 protein||Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine||Mammalian cell||Detail|
Pre-made EZH2 viral vector in GM Promise-ORFTM
|Cat No.||Products name||NM ID||Species||Type||Detail|
|vGMLV000239||human EZH2 Lentivirus particle||NM_004456.4||Human||Lentivirus particle||Detail|
|pGMLV000587||human EZH2 Lentivirus plasmid||NM_004456.4||Human||Lentivirus plasmid||Detail|
|vGMLV000587||human EZH2 Lentivirus particle||NM_004456.4||Human||Lentivirus particle||Detail|
|pGMLV000239||human EZH2 Lentivirus plasmid||NM_004456.4||Human||Lentivirus plasmid||Detail|
|pGMAD000205||mouse Ezh2 Adenovirus plasmid||NM_007971.2||Mouse||Adenovirus plasmid||Detail|
|pGMAD000643||house mouse Ezh2 Adenovirus plasmid||NM_001146689||House Mouse||Adenovirus plasmid||Detail|
|pGMAD000644||house mouse Ezh2 Adenovirus plasmid||NM_007971||House Mouse||Adenovirus plasmid||Detail|
|pGMAAV000342||house mouse Ezh2 AAV plasmid||NM_007971.2||House Mouse||AAV plasmid||Detail|
|pGMAAV000343||house mouse Ezh2 AAV plasmid||NM_001146689.1||House Mouse||AAV plasmid||Detail|
|vGMAD000205||mouse Ezh2 Adenovirus particle||NM_007971.2||Mouse||Adenovirus particle||Detail|
|vGMAD000643||house mouse Ezh2 Adenovirus particle||NM_001146689||House Mouse||Adenovirus particle||Detail|
|vGMAD000644||house mouse Ezh2 Adenovirus particle||NM_007971||House Mouse||Adenovirus particle||Detail|
|vGMAAV000342||house mouse Ezh2 AAV particle||NM_007971.2||House Mouse||AAV particle||Detail|
|vGMAAV000343||house mouse Ezh2 AAV particle||NM_001146689.1||House Mouse||AAV particle||Detail|
Discover the largest collection of ORF/cDNA expression clones from different species, including human, mouse, rat, and more with GeneMedi's Promise-ORFTM. Our collection of ORFs expression clones come in verified mammalian or viral vectors lentivirus, AAV, and adenovirus) and our Promise-ORFTM viral-ready expression vectors make it easy for you to improve viral vector packaging efficiency or directly transfect mammalian cells, resulting in stronger and easier expression detection. Click to search your GOI
If you want to obtain higher quantities of plasmids (mg), please visit GM TransExcellent Plasmid DNA Rapid Preparation Service.