Rat Kcnd3/Kv4.3 ORF/cDNA clone-Adeno-associate virus(AAV) plasmid (NM_001270962.1)
Pre-made Rat Kcnd3/Kv4.3 Adeno-associated virus expression plasmid (ITR-vector) for Kcnd3 AAV packaging, Kcnd3 AAV production.The purified Rat Kcnd3/Kv4.3 AAV particle serves as an invaluable asset for in-depth in vivo Kcnd3 studies, mechanism of action (MOA) research, and the evolution of Kcnd3-associated gene therapy strategies.
Our GM-AAV ITR vector is optimized with the G-NEXT™ multi-serotypes AAV vector system. Explore the G-NEXT™ system in detail.
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Product information
Catalog No. | Product Name | Plasmid Grade | Plasmid quantity |
---|---|---|---|
pGMAAV000111 | Rat Kcnd3 Adeno-associate virus(AAV) plasmid | Research Grade | 10mg, 50mg, 100mg, 500mg, >1g |
GMP-like Grade | 10mg, 50mg, 100mg, 500mg, >1g | ||
High Quality (HQ) Grade | |||
Seed | 5ug |
Product Description
Catalog ID | pGMAAV000111 |
Gene Name | Kcnd3 |
Accession Number | NM_001270962.1 |
Gene ID | 65195 |
Species | Rat |
Product Type | Adeno-associate virus(AAV) plasmid (overexpression) |
Insert Length | 1968 bp |
Gene Alias | Kv4.3 |
Fluorescent Reporter | EGFP |
Mammalian Cell Selection | |
Fusion Tag | 3xflag (C-Terminal) |
Promoter | CMV |
Resistance | Amplicin |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
Category | Cat No. | Products Name |
---|---|---|
Target Antibody | GM-Tg-g-T74500-Ab | Anti-KCND3/ BRGDA9L/ KCND3S monoclonal antibody |
Target Antigen | GM-Tg-g-T74500-Ag | KCND3 VLP (virus-like particle) |
ORF Viral Vector | pGMLV001712 | Human KCND3 Lentivirus plasmid |
ORF Viral Vector | pGMAAV000111 | Rat Kcnd3 Adeno-associate virus(AAV) plasmid |
ORF Viral Vector | vGMLV001712 | Human KCND3 Lentivirus particle |
ORF Viral Vector | vGMAAV000111 | Rat Kcnd3 Adeno-associate virus(AAV) particle |
Target information
Target ID | GM-T74500 |
Target Name | KCND3 |
Gene ID | 3752, 56543, 641437, 65195, 101095595, 403758, 539739, 100058973 |
Gene Symbol and Synonyms | BRGDA9,KCND3,KCND3L,KCND3S,Kncd3,KSHIVB,KV4.3,SCA19,SCA22 |
Uniprot Accession | Q9UK17 |
Uniprot Entry Name | KCND3_HUMAN |
Protein Sub-location | Transmembrane Protein |
Category | Therapeutics Target |
Disease | Not Available |
Gene Ensembl | ENSG00000171385 |
Target Classification | Ion Channel |
Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. Four sequence-related potassium channel genes - shaker, shaw, shab, and shal - have been identified in Drosophila, and each has been shown to have human homolog(s). This gene encodes a member of the potassium channel, voltage-gated, shal-related subfamily, members of which form voltage-activated A-type potassium ion channels and are prominent in the repolarization phase of the action potential. This member includes two isoforms with different sizes, which are encoded by alternatively spliced transcript variants of this gene. [provided by RefSeq, Jul 2008]
About GMVC
GMVC (GM Vector Core) is GeneMedi’s unique platform for QbD Viral vectors Processes development and manufacturing. In GMVC, our core expertise lies in the tailored production of viral vectors, including adeno-associated virus (AAV), lentivirus, and adenovirus. Our state-of-the-art facilities are equipped for scalable manufacturing, ensuring high-quality viral vector production to meet both research and therapeutic needs. Our expert team specializes in process development, leveraging innovative technology and extensive industry knowledge to provide clients with tailored solutions that exceed expectations. GMVC will be the ideal partner for scientists and healthcare professionals seeking reliable and efficient viral vector production services.