Rat Kcnd3/Kv4.3 ORF/cDNA clone-Adeno-associate virus(AAV) plasmid (NM_001270962.1)

Pre-made Rat Kcnd3/Kv4.3 Adeno-associated virus expression plasmid (ITR-vector) for Kcnd3 AAV packaging, Kcnd3 AAV production.The purified Rat Kcnd3/Kv4.3 AAV particle serves as an invaluable asset for in-depth in vivo Kcnd3 studies, mechanism of action (MOA) research, and the evolution of Kcnd3-associated gene therapy strategies.

Our GM-AAV ITR vector is optimized with the G-NEXT™ multi-serotypes AAV vector system. Explore the G-NEXT™ system in detail.

Target products collectionGo to KCND3/Kcnd3/Kv4.3 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)



Product information

Catalog No. Product Name Plasmid Grade Plasmid quantity
pGMAAV000111 Rat Kcnd3 Adeno-associate virus(AAV) plasmid Research Grade 10mg, 50mg, 100mg, 500mg, >1g
GMP-like Grade 10mg, 50mg, 100mg, 500mg, >1g
High Quality (HQ) Grade
Seed 5ug


Product Description

Catalog ID pGMAAV000111
Gene Name Kcnd3
Accession Number NM_001270962.1
Gene ID 65195
Species Rat
Product Type Adeno-associate virus(AAV) plasmid (overexpression)
Insert Length 1968 bp
Gene Alias Kv4.3
Fluorescent Reporter EGFP
Mammalian Cell Selection
Fusion Tag 3xflag (C-Terminal)
Promoter CMV
Resistance Amplicin

Reference




    Data / case study


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    Associated products


    Category Cat No. Products Name
    Target Antibody GM-Tg-g-T74500-Ab Anti-KCND3/ BRGDA9L/ KCND3S monoclonal antibody
    Target Antigen GM-Tg-g-T74500-Ag KCND3 VLP (virus-like particle)
    ORF Viral Vector pGMLV001712 Human KCND3 Lentivirus plasmid
    ORF Viral Vector pGMAAV000111 Rat Kcnd3 Adeno-associate virus(AAV) plasmid
    ORF Viral Vector vGMLV001712 Human KCND3 Lentivirus particle
    ORF Viral Vector vGMAAV000111 Rat Kcnd3 Adeno-associate virus(AAV) particle


    Target information

    Target ID GM-T74500
    Target Name KCND3
    Gene ID 3752, 56543, 641437, 65195, 101095595, 403758, 539739, 100058973
    Gene Symbol and Synonyms BRGDA9,KCND3,KCND3L,KCND3S,Kncd3,KSHIVB,KV4.3,SCA19,SCA22
    Uniprot Accession Q9UK17
    Uniprot Entry Name KCND3_HUMAN
    Protein Sub-location Transmembrane Protein
    Category Therapeutics Target
    Disease Not Available
    Gene Ensembl ENSG00000171385
    Target Classification Ion Channel

    Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. Four sequence-related potassium channel genes - shaker, shaw, shab, and shal - have been identified in Drosophila, and each has been shown to have human homolog(s). This gene encodes a member of the potassium channel, voltage-gated, shal-related subfamily, members of which form voltage-activated A-type potassium ion channels and are prominent in the repolarization phase of the action potential. This member includes two isoforms with different sizes, which are encoded by alternatively spliced transcript variants of this gene. [provided by RefSeq, Jul 2008]



    About GMVC

    GDU



    GMVC (GM Vector Core) is GeneMedi’s unique platform for QbD Viral vectors Processes development and manufacturing. In GMVC, our core expertise lies in the tailored production of viral vectors, including adeno-associated virus (AAV), lentivirus, and adenovirus. Our state-of-the-art facilities are equipped for scalable manufacturing, ensuring high-quality viral vector production to meet both research and therapeutic needs. Our expert team specializes in process development, leveraging innovative technology and extensive industry knowledge to provide clients with tailored solutions that exceed expectations. GMVC will be the ideal partner for scientists and healthcare professionals seeking reliable and efficient viral vector production services.