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Rat Abcg2/Bcrp/ BCRP1 ORF/cDNA clone-Adeno-associate virus(AAV) plasmid (NM_181381.2)
Pre-made Rat Abcg2/Bcrp/ BCRP1 Adeno-associated virus expression plasmid (ITR-vector) for Abcg2 AAV packaging, Abcg2 AAV production.The purified Rat Abcg2/Bcrp/ BCRP1 AAV particle serves as an invaluable asset for in-depth in vivo Abcg2 studies, mechanism of action (MOA) research, and the evolution of Abcg2-associated gene therapy strategies.
Our GM-AAV ITR vector is optimized with the G-NEXT™ multi-serotypes AAV vector system. Explore the G-NEXT™ system in detail.
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(antibodies,
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Product information
| Catalog No. | Product Name | Plasmid Grade | Plasmid quantity |
|---|---|---|---|
| pGMAAV000265 | Rat Abcg2 Adeno-associate virus(AAV) plasmid | Research Grade | 10mg, 50mg, 100mg, 500mg, >1g |
| GMP-like Grade | 10mg, 50mg, 100mg, 500mg, >1g | ||
| High Quality (HQ) Grade | |||
| Seed | 5ug |
Product Description
| Catalog ID | pGMAAV000265 |
| Gene Name | Abcg2 |
| Accession Number | NM_181381.2 |
| Gene ID | 312382 |
| Species | Rat |
| Product Type | Adeno-associate virus(AAV) plasmid (overexpression) |
| Insert Length | 1974 bp |
| Gene Alias | Bcrp, BCRP1 |
| Fluorescent Reporter | ZsGreen |
| Mammalian Cell Selection | Puromyocin |
| Fusion Tag | 3xflag (C-Terminal) |
| Promoter | CMV |
| Resistance | Amplicin |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
|---|---|---|
| Target Antibody | GM-Tg-g-T56556-Ab | Anti-ABCG2/ ABC15/ ABCP monoclonal antibody |
| Target Antigen | GM-Tg-g-T56556-Ag | ABCG2 VLP (virus-like particle) |
| ORF Viral Vector | pGMLV000231 | Human ABCG2 Lentivirus plasmid |
| ORF Viral Vector | pGMLV000861 | Human ABCG2 Lentivirus plasmid |
| ORF Viral Vector | pGMLV000862 | Human ABCG2 Lentivirus plasmid |
| ORF Viral Vector | pGMLV001806 | Human ABCG2 Lentivirus plasmid |
| ORF Viral Vector | pGMAAV000265 | Rat Abcg2 Adeno-associate virus(AAV) plasmid |
| ORF Viral Vector | vGMLV000231 | Human ABCG2 Lentivirus particle |
| ORF Viral Vector | vGMLV000861 | Human ABCG2 Lentivirus particle |
| ORF Viral Vector | vGMLV000862 | Human ABCG2 Lentivirus particle |
| ORF Viral Vector | vGMLV001806 | Human ABCG2 Lentivirus particle |
| ORF Viral Vector | vGMAAV000265 | Rat Abcg2 Adeno-associate virus(AAV) particle |
| ORF Viral Vector | pGMLV002213 | Rat Abcg2 Lentivirus plasmid |
| ORF Viral Vector | pGMLV002216 | Human ABCG2 Lentivirus plasmid |
Target information
| Target ID | GM-T56556 |
| Target Name | ABCG2 |
| Gene ID | 9429, 26357, 574307, 312382, 101094017, 478472, 536203, 100034164 |
| Gene Symbol and Synonyms | ABC15,ABCG2,ABCG3,ABCP,BCRP,BCRP1,BMDP,CD338,CDw338,CDw388,EST157481,GOUT1,MRX,MXR,MXR-1,MXR1,UAQTL1 |
| Uniprot Accession | Q9UNQ0 |
| Uniprot Entry Name | ABCG2_HUMAN |
| Protein Sub-location | Transmembrane Protein |
| Category | Therapeutics Target |
| Disease | Cancer |
| Gene Ensembl | ENSG00000118777 |
| Target Classification | Tumor-associated antigen (TAA) |
The membrane-associated protein encoded by this gene is included in the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the White subfamily. Alternatively referred to as a breast cancer resistance protein, this protein functions as a xenobiotic transporter which may play a major role in multi-drug resistance. It likely serves as a cellular defense mechanism in response to mitoxantrone and anthracycline exposure. Significant expression of this protein has been observed in the placenta, which may suggest a potential role for this molecule in placenta tissue. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2012]
About GMVC
GMVC (GM Vector Core) is GeneMedi’s unique platform for QbD Viral vectors Processes development and manufacturing. In GMVC, our core expertise lies in the tailored production of viral vectors, including adeno-associated virus (AAV), lentivirus, and adenovirus. Our state-of-the-art facilities are equipped for scalable manufacturing, ensuring high-quality viral vector production to meet both research and therapeutic needs. Our expert team specializes in process development, leveraging innovative technology and extensive industry knowledge to provide clients with tailored solutions that exceed expectations. GMVC will be the ideal partner for scientists and healthcare professionals seeking reliable and efficient viral vector production services.
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