Rat Hif1a/MOP1 ORF/cDNA clone-Adeno-associate virus(AAV) plasmid (NM_024359.1)
Pre-made Rat Hif1a/MOP1 Adeno-associated virus expression plasmid (ITR-vector) for Hif1a AAV packaging, Hif1a AAV production.The purified Rat Hif1a/MOP1 AAV particle serves as an invaluable asset for in-depth in vivo Hif1a studies, mechanism of action (MOA) research, and the evolution of Hif1a-associated gene therapy strategies.
Our GM-AAV ITR vector is optimized with the G-NEXT™ multi-serotypes AAV vector system. Explore the G-NEXT™ system in detail.
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Product information
Catalog No. | Product Name | Plasmid Grade | Plasmid quantity |
---|---|---|---|
pGMAAV000349 | Rat Hif1a Adeno-associate virus(AAV) plasmid | Research Grade | 10mg, 50mg, 100mg, 500mg, >1g |
GMP-like Grade | 10mg, 50mg, 100mg, 500mg, >1g | ||
High Quality (HQ) Grade | |||
Seed | 5ug |
Product Description
Catalog ID | pGMAAV000349 |
Gene Name | Hif1a |
Accession Number | NM_024359.1 |
Gene ID | 29560 |
Species | Rat |
Product Type | Adeno-associate virus(AAV) plasmid (overexpression) |
Insert Length | 2472 bp |
Gene Alias | MOP1 |
Fluorescent Reporter | |
Mammalian Cell Selection | Null |
Fusion Tag | 3xflag (C-Terminal) |
Promoter | CMV |
Resistance | Amplicin |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
Target information
Target ID | GM-IP0067 |
Target Name | HIF-1A |
Gene ID | 3091, 15251, 704678, 29560, 101083686, 480348, 281814, 100061166 |
Gene Symbol and Synonyms | bHLHe78,HIF-1-alpha,HIF-1A,HIF-1alpha,HIF1,HIF1-ALPHA,HIF1A,HIF1alpha,MOP1,PASD8 |
Uniprot Accession | Q16665 |
Uniprot Entry Name | HIF1A_HUMAN |
Protein Sub-location | Introcelluar Protein |
Category | Therapeutics Target |
Disease | Cancer |
Gene Ensembl | ENSG00000100644 |
Target Classification | Tumor-associated antigen (TAA) |
This gene encodes the alpha subunit of transcription factor hypoxia-inducible factor-1 (HIF-1), which is a heterodimer composed of an alpha and a beta subunit. HIF-1 functions as a master regulator of cellular and systemic homeostatic response to hypoxia by activating transcription of many genes, including those involved in energy metabolism, angiogenesis, apoptosis, and other genes whose protein products increase oxygen delivery or facilitate metabolic adaptation to hypoxia. HIF-1 thus plays an essential role in embryonic vascularization, tumor angiogenesis and pathophysiology of ischemic disease. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Jul 2011]
About GMVC
GMVC (GM Vector Core) is GeneMedi’s unique platform for QbD Viral vectors Processes development and manufacturing. In GMVC, our core expertise lies in the tailored production of viral vectors, including adeno-associated virus (AAV), lentivirus, and adenovirus. Our state-of-the-art facilities are equipped for scalable manufacturing, ensuring high-quality viral vector production to meet both research and therapeutic needs. Our expert team specializes in process development, leveraging innovative technology and extensive industry knowledge to provide clients with tailored solutions that exceed expectations. GMVC will be the ideal partner for scientists and healthcare professionals seeking reliable and efficient viral vector production services.