Rat Lcn2/Sip24 ORF/cDNA clone-Adeno-associate virus(AAV) particle (NM_130741.1)

Pre-made Rat Lcn2/Sip24 Adeno-associated virus particle for Lcn2 in-vivo study, mechanism of action (MOA) research and Lcn2-associated gene therapy development.

At GM Vector Core (GMVC), we stand at the forefront of custom AAV development and produce distinct grades of AAVs employing state-of-the-art methodologies. Uncover more about our expertise.

Target products collectionGo to LCN2/Lcn2/Sip24 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)



Product information

Catalog No. Product Name AAV serotype AAV Grade AAV quantity
vGMAAV000092 Rat Lcn2 Adeno-associate virus(AAV) particle AAV1, AAV2, AAV2 variant (Y444F), AAV2 variant (Y272F, Y444F, Y500F, Y730F), AAV2 variant (Y444F, Y730F, Y500F, Y272F, Y704F, Y252F), AAV2 variant(AAV2.7m8), AAV5, AAV6, AAV8, AAV8-1m, AAV8-2m, AAV8 variant (Y733F, Y447F, Y275), AAV9, AAV-Rh.10, AAV-DJ, AAV-DJ/8, AAV-Retro (Retrograde), AAV9-PHP.B, AAV9-PHP.eB, AAV9-PHP.S, AAV-BR1, AAV-2i8, AAV-SIG, AAV-VEC, AAV4, AAV6.2, AAV6.2FF Pilot Grade 1.0E+12VG/ml
5.0E+12VG/ml
1E+13VG/ml
5E+13VG/ml
1E+14VG/ml
Research Grade 1.0E+12VG/ml
5.0E+12VG/ml
1E+13VG/ml
5E+13VG/ml
1E+14VG/ml
GMP-like Grade inquiry
GMP Grade inquiry


Product Description

Catalog ID vGMAAV000092
Gene Name Lcn2
Accession Number NM_130741.1
Gene ID 170496
Species Rat
Product Type Adeno-associate virus(AAV) particle (overexpression)
Insert Length 597 bp
Gene Alias Sip24
Fluorescent Reporter EGFP
Mammalian Cell Selection
Fusion Tag 3xflag (C-Terminal)
Promoter CMV
Resistance Amplicin

Reference




    Data / case study


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    Associated products


    Category Cat No. Products Name
    Target Antibody GM-Tg-g-T72010-Ab Anti-NGAL/ LCN2/ 24p3 functional antibody
    Target Antigen GM-Tg-g-T72010-Ag LCN2 protein
    ORF Viral Vector pGMLV001321 Human LCN2 Lentivirus plasmid
    ORF Viral Vector pGMAD001066 Human LCN2 Adenovirus plasmid
    ORF Viral Vector pGMAAV000092 Rat Lcn2 Adeno-associate virus(AAV) plasmid
    ORF Viral Vector pGMPC000637 Human LCN2 Mammalian (Non-Viral Vector) plasmid
    ORF Viral Vector pGMPC000792 Human LCN2 Mammalian (Non-Viral Vector) plasmid
    ORF Viral Vector pGMLP002859 Human LCN2 Lentivirus plasmid
    ORF Viral Vector vGMLV001321 Human LCN2 Lentivirus particle
    ORF Viral Vector vGMAD001066 Human LCN2 Adenovirus particle
    ORF Viral Vector vGMAAV000092 Rat Lcn2 Adeno-associate virus(AAV) particle
    ORF Viral Vector vGMLP002859 Human LCN2 Lentivirus particle


    Target information

    Target ID GM-T72010
    Target Name LCN2
    Gene ID 3934, 16819, 697208, 170496, 491320, 526639, 100070310
    Gene Symbol and Synonyms 24p3,LCN2,MSFI,NGAL,NRL,p25,Sip24
    Uniprot Accession P80188
    Uniprot Entry Name NGAL_HUMAN
    Protein Sub-location Secreted Protein/Potential Cytokines
    Category Therapeutics Target, Diagnostics Biomarker
    Disease Prostate Cancer, Complications of kidney transplant, Congenital hydronephrosis, Congenital occlusion of ureteropelvic junction, Contact with and (suspected) exposure to hazardous aromatic compounds, Contrast - Induced Nephropathy, Delayed Graft Function, Dent disease, Diabetic Nephropathy, HIV-Associated Nephropathy, Hydronephrosis, Hypertension, Impaired renal function disease, Injury to Kidney, Intraoperative Renal Injury, Kidney transplant rejection, Lupus Glomerulonephritis, Neonatal urinary tract infection, Nephrectomy, Nephropathy induced by other drugs, medicaments and biological substances, Nephrotic syndrome, Nephrotic syndrome with diffuse membranous glomerulonephritis, Proteinuria, Renal fibrosis, Renovascular hypertension, Sepsis due to Enterococcus, Systemic inflammatory response syndrome (SIRS) of non-infectious origin with acute organ dysfunction, Systemic lupus erythematosus (SLE), Transplanted Heart Complication, Type 1 diabetes mellitus with diabetic nephropathy, Acute pancreatitis, Asphyxia neonatorum, Autosomal Dominant Polycystic Kidney Disease, Cardiogenic shock, Chronic Kidney Disease, Type 2 diabetes mellitus, Vasculitis, Vesicoureteral reflux
    Gene Ensembl ENSG00000148346
    Target Classification Not Available

    This gene encodes a protein that belongs to the lipocalin family. Members of this family transport small hydrophobic molecules such as lipids, steroid hormones and retinoids. The protein encoded by this gene is a neutrophil gelatinase-associated lipocalin and plays a role in innate immunity by limiting bacterial growth as a result of sequestering iron-containing siderophores. The presence of this protein in blood and urine is an early biomarker of acute kidney injury. This protein is thought to be be involved in multiple cellular processes, including maintenance of skin homeostasis, and suppression of invasiveness and metastasis. Mice lacking this gene are more susceptible to bacterial infection than wild type mice. [provided by RefSeq, Sep 2015]



    About GMVC

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    GMVC (GM Vector Core) is GeneMedi’s unique platform for QbD Viral vectors Processes development and manufacturing. In GMVC, our core expertise lies in the tailored production of viral vectors, including adeno-associated virus (AAV), lentivirus, and adenovirus. Our state-of-the-art facilities are equipped for scalable manufacturing, ensuring high-quality viral vector production to meet both research and therapeutic needs. Our expert team specializes in process development, leveraging innovative technology and extensive industry knowledge to provide clients with tailored solutions that exceed expectations. GMVC will be the ideal partner for scientists and healthcare professionals seeking reliable and efficient viral vector production services.