Rat Ucp2 ORF/cDNA clone-Adeno-associate virus(AAV) particle (NM_019354.3)
Pre-made Rat Ucp2/ Adeno-associated virus particle for Ucp2 in-vivo study, mechanism of action (MOA) research and Ucp2-associated gene therapy development.
At GM Vector Core (GMVC), we stand at the forefront of custom AAV development and produce distinct grades of AAVs employing state-of-the-art methodologies. Uncover more about our expertise.
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Product information
Catalog No. | Product Name | AAV serotype | AAV Grade | AAV quantity |
vGMAAV000146 | Rat Ucp2 Adeno-associate virus(AAV) particle | AAV1, AAV2, AAV2 variant (Y444F), AAV2 variant (Y272F, Y444F, Y500F, Y730F), AAV2 variant (Y444F, Y730F, Y500F, Y272F, Y704F, Y252F), AAV2 variant(AAV2.7m8), AAV5, AAV6, AAV8, AAV8-1m, AAV8-2m, AAV8 variant (Y733F, Y447F, Y275), AAV9, AAV-Rh.10, AAV-DJ, AAV-DJ/8, AAV-Retro (Retrograde), AAV9-PHP.B, AAV9-PHP.eB, AAV9-PHP.S, AAV-BR1, AAV-2i8, AAV-SIG, AAV-VEC, AAV4, AAV6.2, AAV6.2FF | Pilot Grade | 1.0E+12VG/ml |
5.0E+12VG/ml | ||||
1E+13VG/ml | ||||
5E+13VG/ml | ||||
1E+14VG/ml | ||||
Research Grade | 1.0E+12VG/ml | |||
5.0E+12VG/ml | ||||
1E+13VG/ml | ||||
5E+13VG/ml | ||||
1E+14VG/ml | ||||
GMP-like Grade | inquiry | |||
GMP Grade | inquiry |
Product Description
Catalog ID | vGMAAV000146 |
Gene Name | Ucp2 |
Accession Number | NM_019354.3 |
Gene ID | 54315 |
Species | Rat |
Product Type | Adeno-associate virus(AAV) particle (overexpression) |
Insert Length | 930 bp |
Gene Alias | |
Fluorescent Reporter | |
Mammalian Cell Selection | Null |
Fusion Tag | 3xflag (C-Terminal) |
Promoter | CMV |
Resistance | Amplicin |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
Category | Cat No. | Products Name |
---|---|---|
Target Antibody | GM-Tg-g-T84560-Ab | Anti-UCP2 monoclonal antibody |
Target Antigen | GM-Tg-g-T84560-Ag | UCP2 protein |
ORF Viral Vector | pGMAD000297 | Rat Ucp2 Adenovirus plasmid |
ORF Viral Vector | pGMAAV000146 | Rat Ucp2 Adeno-associate virus(AAV) plasmid |
ORF Viral Vector | pGMAAV000337 | Rat Ucp2 Adeno-associate virus(AAV) plasmid |
ORF Viral Vector | pGMLP000084 | Human UCP2 Lentivirus plasmid |
ORF Viral Vector | vGMAD000297 | Rat Ucp2 Adenovirus particle |
ORF Viral Vector | vGMAAV000146 | Rat Ucp2 Adeno-associate virus(AAV) particle |
ORF Viral Vector | vGMAAV000337 | Rat Ucp2 Adeno-associate virus(AAV) particle |
ORF Viral Vector | vGMLP000084 | Human UCP2 Lentivirus particle |
Target information
Target ID | GM-T84560 |
Target Name | UCP2 |
Gene ID | 7351, 22228, 574198, 54315, 692194, 403576, 281562, 100052144 |
Gene Symbol and Synonyms | BMIQ4,SLC25A8,UCP 2,UCP2,UCPH |
Uniprot Accession | P55851 |
Uniprot Entry Name | UCP2_HUMAN |
Protein Sub-location | Introcelluar Protein |
Category | Therapeutics Target |
Disease | Not Available |
Gene Ensembl | ENSG00000175567 |
Target Classification | Not Available |
Mitochondrial uncoupling proteins (UCP) are members of the larger family of mitochondrial anion carrier proteins (MACP). UCPs separate oxidative phosphorylation from ATP synthesis with energy dissipated as heat, also referred to as the mitochondrial proton leak. UCPs facilitate the transfer of anions from the inner to the outer mitochondrial membrane and the return transfer of protons from the outer to the inner mitochondrial membrane. They also reduce the mitochondrial membrane potential in mammalian cells. Tissue specificity occurs for the different UCPs and the exact methods of how UCPs transfer H+/OH- are not known. UCPs contain the three homologous protein domains of MACPs. This gene is expressed in many tissues, with the greatest expression in skeletal muscle. It is thought to play a role in nonshivering thermogenesis, obesity and diabetes. Chromosomal order is 5'-UCP3-UCP2-3'. [provided by RefSeq, Jul 2008]
About GMVC
GMVC (GM Vector Core) is GeneMedi’s unique platform for QbD Viral vectors Processes development and manufacturing. In GMVC, our core expertise lies in the tailored production of viral vectors, including adeno-associated virus (AAV), lentivirus, and adenovirus. Our state-of-the-art facilities are equipped for scalable manufacturing, ensuring high-quality viral vector production to meet both research and therapeutic needs. Our expert team specializes in process development, leveraging innovative technology and extensive industry knowledge to provide clients with tailored solutions that exceed expectations. GMVC will be the ideal partner for scientists and healthcare professionals seeking reliable and efficient viral vector production services.