Rat Ascl1/Mash1 ORF/cDNA clone-Adeno-associate virus(AAV) particle (NM_022384.1)
Pre-made Rat Ascl1/Mash1 Adeno-associated virus particle for Ascl1 in-vivo study, mechanism of action (MOA) research and Ascl1-associated gene therapy development.
At GM Vector Core (GMVC), we stand at the forefront of custom AAV development and produce distinct grades of AAVs employing state-of-the-art methodologies. Uncover more about our expertise.
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Product information
Catalog No. | Product Name | AAV serotype | AAV Grade | AAV quantity |
vGMAAV000356 | Rat Ascl1 Adeno-associate virus(AAV) particle | AAV1, AAV2, AAV2 variant (Y444F), AAV2 variant (Y272F, Y444F, Y500F, Y730F), AAV2 variant (Y444F, Y730F, Y500F, Y272F, Y704F, Y252F), AAV2 variant(AAV2.7m8), AAV5, AAV6, AAV8, AAV8-1m, AAV8-2m, AAV8 variant (Y733F, Y447F, Y275), AAV9, AAV-Rh.10, AAV-DJ, AAV-DJ/8, AAV-Retro (Retrograde), AAV9-PHP.B, AAV9-PHP.eB, AAV9-PHP.S, AAV-BR1, AAV-2i8, AAV-SIG, AAV-VEC, AAV4, AAV6.2, AAV6.2FF | Pilot Grade | 1.0E+12VG/ml |
5.0E+12VG/ml | ||||
1E+13VG/ml | ||||
5E+13VG/ml | ||||
1E+14VG/ml | ||||
Research Grade | 1.0E+12VG/ml | |||
5.0E+12VG/ml | ||||
1E+13VG/ml | ||||
5E+13VG/ml | ||||
1E+14VG/ml | ||||
GMP-like Grade | inquiry | |||
GMP Grade | inquiry |
Product Description
Catalog ID | vGMAAV000356 |
Gene Name | Ascl1 |
Accession Number | NM_022384.1 |
Gene ID | 64186 |
Species | Rat |
Product Type | Adeno-associate virus(AAV) particle (overexpression) |
Insert Length | 702 bp |
Gene Alias | Mash1 |
Fluorescent Reporter | mcherry |
Mammalian Cell Selection | |
Fusion Tag | 3xflag (C-Terminal) |
Promoter | CMV |
Resistance | Amplicin |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
Category | Cat No. | Products Name |
---|---|---|
Target Antibody | GM-Tg-g-SE1510-Ab | Anti-ASCL1/ ASH1/ HASH1 functional antibody |
Target Antigen | GM-Tg-g-SE1510-Ag | ASCL1 protein |
ORF Viral Vector | pGMAAV000356 | Rat Ascl1 Adeno-associate virus(AAV) plasmid |
ORF Viral Vector | pGMLP004565 | Human ASCL1 Lentivirus plasmid |
ORF Viral Vector | vGMAAV000356 | Rat Ascl1 Adeno-associate virus(AAV) particle |
ORF Viral Vector | vGMLP004565 | Human ASCL1 Lentivirus particle |
Target information
Target ID | GM-SE1510 |
Target Name | ASCL1 |
Gene ID | 429, 17172, 698820, 64186, 101081993, 482628, 540473, 100146286 |
Gene Symbol and Synonyms | ASCL1,ASH1,bHLHa46,HASH1,MASH1 |
Uniprot Accession | P50553 |
Uniprot Entry Name | ASCL1_HUMAN |
Protein Sub-location | Secreted Protein/Potential Cytokines |
Category | Not Available |
Disease | Cancer |
Gene Ensembl | ENSG00000139352 |
Target Classification | Tumor-associated antigen (TAA) |
This gene encodes a member of the basic helix-loop-helix (BHLH) family of transcription factors. The protein activates transcription by binding to the E box (5'-CANNTG-3'). Dimerization with other BHLH proteins is required for efficient DNA binding. This protein plays a role in the neuronal commitment and differentiation and in the generation of olfactory and autonomic neurons. Mutations in this gene may contribute to the congenital central hypoventilation syndrome (CCHS) phenotype in rare cases. [provided by RefSeq, Jul 2008]
About GMVC
GMVC (GM Vector Core) is GeneMedi’s unique platform for QbD Viral vectors Processes development and manufacturing. In GMVC, our core expertise lies in the tailored production of viral vectors, including adeno-associated virus (AAV), lentivirus, and adenovirus. Our state-of-the-art facilities are equipped for scalable manufacturing, ensuring high-quality viral vector production to meet both research and therapeutic needs. Our expert team specializes in process development, leveraging innovative technology and extensive industry knowledge to provide clients with tailored solutions that exceed expectations. GMVC will be the ideal partner for scientists and healthcare professionals seeking reliable and efficient viral vector production services.