Rat Ascl1/Mash1 ORF/cDNA clone-Adeno-associate virus(AAV) particle (NM_022384.1)

Pre-made Rat Ascl1/Mash1 Adeno-associated virus particle for Ascl1 in-vivo study, mechanism of action (MOA) research and Ascl1-associated gene therapy development.

At GM Vector Core (GMVC), we stand at the forefront of custom AAV development and produce distinct grades of AAVs employing state-of-the-art methodologies. Uncover more about our expertise.

Target products collectionGo to ASCL1/Ascl1/Mash1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)



Product information

Catalog No. Product Name AAV serotype AAV Grade AAV quantity
vGMAAV000356 Rat Ascl1 Adeno-associate virus(AAV) particle AAV1, AAV2, AAV2 variant (Y444F), AAV2 variant (Y272F, Y444F, Y500F, Y730F), AAV2 variant (Y444F, Y730F, Y500F, Y272F, Y704F, Y252F), AAV2 variant(AAV2.7m8), AAV5, AAV6, AAV8, AAV8-1m, AAV8-2m, AAV8 variant (Y733F, Y447F, Y275), AAV9, AAV-Rh.10, AAV-DJ, AAV-DJ/8, AAV-Retro (Retrograde), AAV9-PHP.B, AAV9-PHP.eB, AAV9-PHP.S, AAV-BR1, AAV-2i8, AAV-SIG, AAV-VEC, AAV4, AAV6.2, AAV6.2FF Pilot Grade 1.0E+12VG/ml
5.0E+12VG/ml
1E+13VG/ml
5E+13VG/ml
1E+14VG/ml
Research Grade 1.0E+12VG/ml
5.0E+12VG/ml
1E+13VG/ml
5E+13VG/ml
1E+14VG/ml
GMP-like Grade inquiry
GMP Grade inquiry


Product Description

Catalog ID vGMAAV000356
Gene Name Ascl1
Accession Number NM_022384.1
Gene ID 64186
Species Rat
Product Type Adeno-associate virus(AAV) particle (overexpression)
Insert Length 702 bp
Gene Alias Mash1
Fluorescent Reporter mcherry
Mammalian Cell Selection
Fusion Tag 3xflag (C-Terminal)
Promoter CMV
Resistance Amplicin

Reference




    Data / case study


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    Associated products


    Category Cat No. Products Name
    Target Antibody GM-Tg-g-SE1510-Ab Anti-ASCL1/ ASH1/ HASH1 functional antibody
    Target Antigen GM-Tg-g-SE1510-Ag ASCL1 protein
    ORF Viral Vector pGMAAV000356 Rat Ascl1 Adeno-associate virus(AAV) plasmid
    ORF Viral Vector pGMLP004565 Human ASCL1 Lentivirus plasmid
    ORF Viral Vector vGMAAV000356 Rat Ascl1 Adeno-associate virus(AAV) particle
    ORF Viral Vector vGMLP004565 Human ASCL1 Lentivirus particle


    Target information

    Target ID GM-SE1510
    Target Name ASCL1
    Gene ID 429, 17172, 698820, 64186, 101081993, 482628, 540473, 100146286
    Gene Symbol and Synonyms ASCL1,ASH1,bHLHa46,HASH1,MASH1
    Uniprot Accession P50553
    Uniprot Entry Name ASCL1_HUMAN
    Protein Sub-location Secreted Protein/Potential Cytokines
    Category Not Available
    Disease Cancer
    Gene Ensembl ENSG00000139352
    Target Classification Tumor-associated antigen (TAA)

    This gene encodes a member of the basic helix-loop-helix (BHLH) family of transcription factors. The protein activates transcription by binding to the E box (5'-CANNTG-3'). Dimerization with other BHLH proteins is required for efficient DNA binding. This protein plays a role in the neuronal commitment and differentiation and in the generation of olfactory and autonomic neurons. Mutations in this gene may contribute to the congenital central hypoventilation syndrome (CCHS) phenotype in rare cases. [provided by RefSeq, Jul 2008]



    About GMVC

    GDU



    GMVC (GM Vector Core) is GeneMedi’s unique platform for QbD Viral vectors Processes development and manufacturing. In GMVC, our core expertise lies in the tailored production of viral vectors, including adeno-associated virus (AAV), lentivirus, and adenovirus. Our state-of-the-art facilities are equipped for scalable manufacturing, ensuring high-quality viral vector production to meet both research and therapeutic needs. Our expert team specializes in process development, leveraging innovative technology and extensive industry knowledge to provide clients with tailored solutions that exceed expectations. GMVC will be the ideal partner for scientists and healthcare professionals seeking reliable and efficient viral vector production services.