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Rat Ntrk2/RATTRKB1/ Tkrb ORF/cDNA clone-Adeno-associate virus(AAV) particle (NM_001163168)
Pre-made Rat Ntrk2/RATTRKB1/ Tkrb Adeno-associated virus particle for Ntrk2 in-vivo study, mechanism of action (MOA) research and Ntrk2-associated gene therapy development.
At GM Vector Core (GMVC), we stand at the forefront of custom AAV development and produce distinct grades of AAVs employing state-of-the-art methodologies. Uncover more about our expertise.
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Product information
| Catalog No. | Product Name | AAV serotype | AAV Grade | AAV quantity |
| vGMAAV000581 | Rat Ntrk2 Adeno-associate virus(AAV) particle | AAV1, AAV2, AAV2 variant (Y444F), AAV2 variant (Y272F, Y444F, Y500F, Y730F), AAV2 variant (Y444F, Y730F, Y500F, Y272F, Y704F, Y252F), AAV2 variant(AAV2.7m8), AAV5, AAV6, AAV8, AAV8-1m, AAV8-2m, AAV8 variant (Y733F, Y447F, Y275), AAV9, AAV-Rh.10, AAV-DJ, AAV-DJ/8, AAV-Retro (Retrograde), AAV9-PHP.B, AAV9-PHP.eB, AAV9-PHP.S, AAV-BR1, AAV-2i8, AAV-SIG, AAV-VEC, AAV4, AAV6.2, AAV6.2FF | Pilot Grade | 1.0E+12VG/ml |
| 5.0E+12VG/ml | ||||
| 1E+13VG/ml | ||||
| 5E+13VG/ml | ||||
| 1E+14VG/ml | ||||
| Research Grade | 1.0E+12VG/ml | |||
| 5.0E+12VG/ml | ||||
| 1E+13VG/ml | ||||
| 5E+13VG/ml | ||||
| 1E+14VG/ml | ||||
| GMP-like Grade | inquiry | |||
| GMP Grade | inquiry |
Product Description
| Catalog ID | vGMAAV000581 |
| Gene Name | Ntrk2 |
| Accession Number | NM_001163168 |
| Gene ID | 25054 |
| Species | Rat |
| Product Type | Adeno-associate virus(AAV) particle (overexpression) |
| Insert Length | 1431 bp |
| Gene Alias | RATTRKB1, Tkrb, trk-B, trkB, TRKB1 |
| Fluorescent Reporter | ZsGreen |
| Mammalian Cell Selection | Puromyocin |
| Fusion Tag | 3xflag (C-Terminal) |
| Promoter | CMV |
| Resistance | Amplicin |
| Sequence | ATGTCGCCCTGGCCGAGGTGGCATGGACCCGCCATGGCGCGGCTCTGGGGCTTATGCTTGCTGGTCTTGGGCTTCTGGAGGGCTTCTCTTGCCTGCCCCATGTCCTGCAAATGCAGCACCACTAGGATTTGGTGTACCGAGCCTTCTCCTGGCATCGTGGCATTTCCGAGGTTGGAACCTAACAGCATTGACCCAGAGAACATCACCGAAATTCTCATTGCAAACCAGAAAAGGTTAGAAATCATCAATGAAGATGATGTCGAAGCTTACGTGGGGCTGAAAAACCTTACAATTGTGGATTCCGGCTTAAAGTTTGTGGCTTACAAGGCGTTTCTGAAGAACGGCAACCTGCGGCACATCAATTTCACTCGAAACAAGCTGACGAGTTTGTCCAGGAGACATTTCCGCCACCTTGACTTGTCTGACCTGATCCTGACGGGTAATCCGTTCACGTGTTCCTGTGACATCATGTGGCTCAAGACTCTCCAGGAGACGAAATCCAGCCCCGACACTCAGGATTTGTATTGCCTCAATGAGAGCAGCAAGAATACCCCTCTGGCGAACCTGCAGATTCCCAATTGTGGTCTGCCGTCTGCACGTCTGGCCGCTCCTAACCTCACGGTGGAGGAAGGGAAGTCTGTGACCATTTCCTGCAGCGTCGGGGGTGACCCGCTCCCCACCTTGTACTGGGACGTTGGGAATTTGGTTTCCAAACACATGAATGAAACAAGCCACACACAGGGCTCCTTAAGGATAACAAACATTTCATCGGATGACAGTGGGAAACAAATCTCTTGTGTGGCAGAAAACCTCGTTGGAGAAGATCAAGACTCTGTGAACCTCACTGTGCATTTTGCACCAACCATCACATTTCTCGAATCTCCAACCTCAGACCACCACTGGTGCATCCCATTCACTGTGAGAGGCAACCCCAAGCCAGCACTTCAGTGGTTCTACAACGGAGCCATACTGAATGAATCCAAGTACATCTGTACCAAAATACACGTCACCAATCACACGGAGTACCACGGCTGCCTCCAGCTGGATAACCCCACTCATATGAATAATGGAGACTACACCCTAATGGCCAAGAATGAATATGGGAAGGACGAGAGACAGATTTCTGCTCACTTCATGGGCCGGCCTGGAGTTGACTATGAGACAAACCCAAATTACCCTGAAGTCCTCTATGAAGACTGGACCACGCCAACTGACATCGGGGATACTACAAACAAAAGTAATGAGATCCCCTCCACGGATGTTGCTGACCAAACCAATCGGGAGCATCTCTCGGTCTATGCCGTGGTGGTGATTGCCTCTGTGGTAGGATTCTGCCTGCTGGTGATGCTGCTTCTGCTCAAGTTGGCGAGACATTCCAAGTTTGGCATGAAAGGTTTTGTTTTGTTTCATAAGATCCCCCTGGATGGGTAG |
Reference
Data / case study
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Associated products
Target information
| Target ID | GM-T84703 |
| Target Name | TrkB |
| Gene ID | 4915, 18212, 709757, 25054, 101101347, 484147, 505824, 100061700 |
| Gene Symbol and Synonyms | DEE58,EIEE58,GP145-TrkB,GP145-TrkB/GP95-TrkB,NTRK2,OBHD,RATTRKB1,Tkrb,trk-B,TRKB,TRKB1 |
| Uniprot Accession | Q16620 |
| Uniprot Entry Name | NTRK2_HUMAN |
| Protein Sub-location | Transmembrane Protein |
| Category | Therapeutics Target |
| Disease | Cancer |
| Gene Ensembl | ENSG00000148053 |
| Target Classification | Kinase, Tumor-associated antigen (TAA) |
This gene encodes a member of the neurotrophic tyrosine receptor kinase (NTRK) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. Signalling through this kinase leads to cell differentiation. Mutations in this gene have been associated with obesity and mood disorders. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2014]
About GMVC
GMVC (GM Vector Core) is GeneMedi’s unique platform for QbD Viral vectors Processes development and manufacturing. In GMVC, our core expertise lies in the tailored production of viral vectors, including adeno-associated virus (AAV), lentivirus, and adenovirus. Our state-of-the-art facilities are equipped for scalable manufacturing, ensuring high-quality viral vector production to meet both research and therapeutic needs. Our expert team specializes in process development, leveraging innovative technology and extensive industry knowledge to provide clients with tailored solutions that exceed expectations. GMVC will be the ideal partner for scientists and healthcare professionals seeking reliable and efficient viral vector production services.
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