Rat Bmp3/PBMP3 ORF/cDNA clone-Adenovirus particle (NM_017105.1)
Pre-made Rat Bmp3/PBMP3 Adenovirus for Bmp3 overexpression in-vitro and in-vivo. The Bmp3 adenoviral vector excels as a vehicle for transient gene transfection in both stable cell lines and primary cells, including DC cells, macrophages, cardiomyocytes, hepatocytes, and neurons. The purified Bmp3-encoding adenovirus also stands out as a quintessential tool for in vivo studies and vaccine research initiatives.
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Product information
Catalog No. | Product Name | Adenovirus Grade | Adenovirus quantity |
vGMAD000608 | Rat Bmp3 Adenovirus particle | Research Grade-In vitro | 1E+10PFU (1E+10pfu/ml×1ml) |
5E+10PFU (1E+10pfu/ml×5ml) | |||
1E+11PFU (1E+10pfu/ml×10ml) | |||
Research Grade-In vivo | 1E+11PFU (1E+11pfu/ml×1ml) | ||
GMP-like Grade | inquiry | ||
GMP Grade | inquiry |
Product Description
Catalog ID | vGMAD000608 |
Gene Name | Bmp3 |
Accession Number | NM_017105.1 |
Gene ID | 25667 |
Species | Rat |
Product Type | Adenovirus particle (overexpression) |
Insert Length | 1407 bp |
Gene Alias | PBMP3 |
Fluorescent Reporter | Luciferase |
Mammalian Cell Selection | |
Fusion Tag | 3xflag (C-Terminal) |
Promoter | CMV |
Resistance | Amplicin |
Sequence | ATGGCTGGGGCTCGCGGGCTGCTGTGTCTGTGGCTAGGTTGTTTCTGCCTGAACCTGGCACAGGGACAGAGACCAAATTTGCACCTCCCGGGACTCCGCGGGACTGAGTCAAGCGACCGCATGACAGGTGGTGGCCCGAGCCCGGACCTGAGGCCTCACGACAAGGTGTCAGAGCATATGCTGTGGCTCTATGACAGGTACAGCGGCAGCAACAGAGCCCAGGCTACCCGGACACCGGGCTCGCAGCTCCCGGGTCCCCAACCCCTGCGTGGCGGTAACACGGTTCGTAGCTTCAGAGCCGCAGCCGCAGGAACTCTTCAAAGAAAGGGCTTGCACACTTTTAATCTGACTTCTCTAACCAAGTCTGAGAACATTTTGTCAGCCACACTGTATTTCTACATTGGAGAATTGGTGAACACCAGTGTGAACTGTCCAGAATCCCAAGGTTGTTCCCATGACAGCCAGAGACAACACATCCAGATAGACCTCTCTGCATGGACCCTCCAATCCAACCAAAGCCAGCTCTTGGGTCATCTGTCAGTAGATACGGCCAAACCTTATAGAGACAGCATGTCTTGGCTGTCAAAAGACATCACTCAGCTCTTACGGAAGGCCAAGCAAGACGAGGAGTTTCTCATAGGATTTAACATTACCTCCAGAGCACACGAGCTTCCCAAGAGGATGCTGCTTTTCCCGGAACCTTATATCTTGGTGTATGCCAACGATGCCGCCATTTGTGAGCCTGAAAGCGTGGTATCTAGCCTACAGAGACACCGCGATTTCACAGCAGGAACTGTGCCCAGACTGGATAGCCACGTCAGAGAAGCCCTCTCTGTTGAGAGGAGGAAGAAGCGCTCTACTGGGATCTTGTTGCCATTGCAGAACAACGAGCTCCCTGGGGCCGAGTATCAGTACAAGGAGGCTGGAGTGTGGGAGGAGAGAAAGCCTTACAAGAGCCTTCAGACTCAGCCTCCTGAAAAGAGCCGGAGCAAAAAGAAACAGAGGAAAGGGCCTCATCAAAAGGGACAGACACTGCAGTTTGATGAGCAGACACTGAAGAAGGCGAGGCGAAAGCAGTGGATCGAGCCTCGGAACTGTGCCCGCAGGTACCTTAAAGTGGACTTTGCCGATATTGGCTGGAGCGAATGGATTATCTCCCCCAAGTCATTTGATGCCTACTATTGCTCCGGAGCCTGCCAGTTCCCCATGCCAAAGTCTTTGAAGCCATCAAATCACGCCACCATCCAGAGCATAGTGAGAGCCGTGGGGGTCGTCTCTGGGATTCCTGAGCCCTGCTGTGTTCCGGAGAAGATGTCCTCGCTCAGCATCTTGTTCTTTGACGAGAACAAGAATGTGGTCCTCAAAGTCTATCCTAACATGACAGTAGACTCTTGTGCTTGTAGATAA |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
Category | Cat No. | Products Name |
---|---|---|
Target Antibody | GM-Tg-g-SE0685-Ab | Anti-BMP3/ BMP-3A functional antibody |
Target Antigen | GM-Tg-g-SE0685-Ag | BMP3 protein |
Cytokine | cks-Tg-g-GM-SE0685 | bone morphogenetic protein 3 (BMP3) protein & antibody |
ORF Viral Vector | pGMAD000608 | Rat Bmp3 Adenovirus plasmid |
ORF Viral Vector | pGMPC000084 | Human BMP3 Mammalian (Non-Viral Vector) plasmid |
ORF Viral Vector | vGMAD000608 | Rat Bmp3 Adenovirus particle |
Target information
Target ID | GM-SE0685 |
Target Name | BMP3 |
Gene ID | 651, 110075, 695432, 25667, 101093182, 100855862, 539527, 100060322 |
Gene Symbol and Synonyms | 9530029I04Rik,BMP-3,BMP-3A,BMP3,PBMP3 |
Uniprot Accession | P12645 |
Uniprot Entry Name | BMP3_HUMAN |
Protein Sub-location | Secreted Protein/Potential Cytokines |
Category | Cytokine Target |
Disease | Colorectal Cancer |
Gene Ensembl | ENSG00000152785 |
Target Classification | Not Available |
This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein suppresses osteoblast differentiation, and negatively regulates bone density, by modulating TGF-beta receptor availability to other ligands. [provided by RefSeq, Jul 2016]
About GMVC
GMVC (GM Vector Core) is GeneMedi’s unique platform for QbD Viral vectors Processes development and manufacturing. In GMVC, our core expertise lies in the tailored production of viral vectors, including adeno-associated virus (AAV), lentivirus, and adenovirus. Our state-of-the-art facilities are equipped for scalable manufacturing, ensuring high-quality viral vector production to meet both research and therapeutic needs. Our expert team specializes in process development, leveraging innovative technology and extensive industry knowledge to provide clients with tailored solutions that exceed expectations. GMVC will be the ideal partner for scientists and healthcare professionals seeking reliable and efficient viral vector production services.