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Rat App/Abeta ORF/cDNA clone-Adenovirus particle (NM_019288.2)
Pre-made Rat App/Abeta Adenovirus for App overexpression in-vitro and in-vivo. The App adenoviral vector excels as a vehicle for transient gene transfection in both stable cell lines and primary cells, including DC cells, macrophages, cardiomyocytes, hepatocytes, and neurons. The purified App-encoding adenovirus also stands out as a quintessential tool for in vivo studies and vaccine research initiatives.
At GM Vector Core (GMVC), we provide bespoke adenovirus development and manufacture various grades of adenoviruses utilizing cutting-edge techniques. Dive deeper into our offerings.
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Product information
| Catalog No. | Product Name | Adenovirus Grade | Adenovirus quantity |
| vGMAD000999 | Rat App Adenovirus particle | Research Grade-In vitro | 1E+10PFU (1E+10pfu/ml×1ml) |
| 5E+10PFU (1E+10pfu/ml×5ml) | |||
| 1E+11PFU (1E+10pfu/ml×10ml) | |||
| Research Grade-In vivo | 1E+11PFU (1E+11pfu/ml×1ml) | ||
| GMP-like Grade | inquiry | ||
| GMP Grade | inquiry |
Product Description
| Catalog ID | vGMAD000999 |
| Gene Name | App |
| Accession Number | NM_019288.2 |
| Gene ID | 54226 |
| Species | Rat |
| Product Type | Adenovirus particle (overexpression) |
| Insert Length | 2313 bp |
| Gene Alias | Abeta |
| Fluorescent Reporter | |
| Mammalian Cell Selection | Null |
| Fusion Tag | 3xflag (C-Terminal) |
| Promoter | CMV |
| Resistance | Amplicin |
| Sequence | ATGCTGCCCAGCCTGGCACTGCTCCTGCTGGCCGCCTGGACGGTTCGGGCTCTGGAGGTGCCCACTGATGGCAATGCCGGTCTGCTGGCAGAACCCCAGATCGCCATGTTCTGTGGTAAACTCAACATGCACATGAATGTGCAGAATGGAAAATGGGAGTCAGACCCATCAGGGACCAAAACCTGCATTGGCACCAAGGAGGGAATCCTGCAGTACTGCCAAGAGGTCTACCCTGAACTGCAGATCACAAACGTGGTGGAAGCCAACCAGCCAGTGACCATCCAGAACTGGTGCAAGCGGGGCCGCAAGCAGTGCAAGACGCACACCCACATCGTGATTCCTTACCGGTGCCTAGTTGGTGAGTTTGTAAGCGATGCCCTTCTCGTGCCCGACAAGTGCAAGTTTCTACACCAGGAGCGGATGGACGTTTGTGAGACCCATCTTCACTGGCATACTGTTGCCAAAGAGACATGCAGTGAGAAGAGCACTAACTTGCACGACTATGGCATGCTGCTGCCCTGTGGCATCGACAAGTTCCGAGGGGTCGAGTTCGTGTGCTGCCCGTTGGCGGAGGAGAGCGACAGCATCGATTCTGCGGACGCAGAGGAGGACGACTCCGATGTCTGGTGGGGTGGAGCGGACACAGACTATGCTGATGGCGGTGAAGACAAAGTCGTAGAAGTAGCCGAAGAGGAGGAAGTGGCCGATGTTGAGGAAGAAGAAGCTGAGGATGACGAGGATGTGGAGGATGGGGATGAGGTGGAGGAGGAGGCCGAGGAGCCCTACGAAGAGGCCACAGAGAGAACAACCAGCATTGCCACCACTACCACAACTACCACTGAGTCTGTGGAGGAGGTAGTCCGAGAGGTGTGCTCTGAACAAGCTGAGACCGGGCCATGCCGTGCAATGATCTCCCGCTGGTACTTTGATGTCACTGAAGGAAAGTGCGCCCCATTCTTTTACGGCGGATGTGGCGGCAACAGGAACAACTTTGACACTGAAGAGTACTGCATGGCGGTGTGTGGCAGCGTGTCATCCCAAAGTTTACTCAAGACTACCAGTGAACCTCTTCCCCAAGATCCGGTTAAACTTCCCACGACGGCAGCCAGCACCCCTGACGCAGTCGACAAGTACCTGGAGACCCCCGGAGATGAGAACGAGCACGCCCATTTCCAGAAAGCCAAAGAGAGGTTGGAAGCCAAGCACCGAGAGAGAATGTCCCAGGTCATGAGAGAATGGGAGGAGGCAGAACGTCAAGCCAAGAATTTGCCCAAAGCTGACAAGAAGGCCGTTATCCAGCATTTCCAGGAGAAAGTGGAATCTCTGGAACAGGAAGCAGCCAACGAGAGGCAGCAGCTTGTAGAGACACACATGGCCAGAGTTGAAGCCATGCTCAATGATCGCCGTCGCCTGGCCCTCGAGAATTACATCACCGCACTGCAGGCGGTGCCTCCAAGGCCTCATCATGTGTTCAACATGCTGAAGAAGTACGTCCGTGCAGAGCAGAAGGACAGACAGCACACCCTAAAGCATTTTGAACATGTGCGCATGGTGGACCCCAAGAAAGCTGCTCAGATCCGGTCCCAGGTTATGACACACCTCCGTGTGATCTACGAGCGCATGAACCAGTCTCTGTCCCTGCTCTACAACGTCCCTGCCGTGGCTGAGGAGATTCAAGATGAAGTTGACGAGCTGCTTCAGAAGGAGCAGAACTACTCCGACGACGTCTTAGCCAACATGATCAGTGAACCCAGAATCAGTTACGGCAACGATGCTCTCATGCCTTCTTTGACTGAAACGAAGACCACTGTGGAGCTCCTTCCCGTGAATGGCGAATTCAGCCTGGATGATCTCCAACCGTGGCATCCTTTTGGGGTGGACTCTGTGCCAGCCAATACAGAAAATGAAGTTGAGCCTGTCGACGCCCGCCCCGCTGCTGACCGAGGACTGACCACTCGACCAGGGTCTGGGTTGACAAACATCAAGACAGAAGAGATCTCAGAAGTGAAGATGGATGCGGAGTTCGGACATGATTCAGGCTTCGAAGTCCGCCATCAAAAACTGGTGTTCTTTGCAGAAGATGTGGGTTCAAACAAAGGTGCCATCATTGGACTCATGGTGGGTGGCGTTGTCATAGCAACAGTGATTGTCATCACCTTGGTGATGCTGAAGAAGAAACAGTACACATCCATCCATCATGGCGTGGTGGAGGTTGACGCTGCTGTGACCCCGGAGGAGCGCCACCTCTCCAAGATGCAGCAGAATGGATATGAGAATCCAACATACAAGTTCTTTGAGCAGATGCAGAACTAA |
Reference
Data / case study
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Associated products
Target information
| Target ID | GM-T87024 |
| Target Name | APP |
| Gene ID | 351, 11820, 100427716, 54226, 101085564, 403407, 280722, 100066294 |
| Gene Symbol and Synonyms | AAA,ABETA,ABPP,AD1,Adap,Ag,alpha-sAPP,APP,APPI,betaApp,CTFgamma,CVAP,E030013M08Rik,PN-II,PN2,preA4 |
| Uniprot Accession | P05067 |
| Uniprot Entry Name | A4_HUMAN |
| Protein Sub-location | Transmembrane Protein |
| Category | Therapeutics Target, INN Index |
| Disease | Not Available |
| Gene Ensembl | ENSG00000142192 |
| Target Classification | Not Available |
This gene encodes a cell surface receptor and transmembrane precursor protein that is cleaved by secretases to form a number of peptides. Some of these peptides are secreted and can bind to the acetyltransferase complex APBB1/TIP60 to promote transcriptional activation, while others form the protein basis of the amyloid plaques found in the brains of patients with Alzheimer disease. In addition, two of the peptides are antimicrobial peptides, having been shown to have bacteriocidal and antifungal activities. Mutations in this gene have been implicated in autosomal dominant Alzheimer disease and cerebroarterial amyloidosis (cerebral amyloid angiopathy). Multiple transcript variants encoding several different isoforms have been found for this gene. [provided by RefSeq, Aug 2014]
About GMVC
GMVC (GM Vector Core) is GeneMedi’s unique platform for QbD Viral vectors Processes development and manufacturing. In GMVC, our core expertise lies in the tailored production of viral vectors, including adeno-associated virus (AAV), lentivirus, and adenovirus. Our state-of-the-art facilities are equipped for scalable manufacturing, ensuring high-quality viral vector production to meet both research and therapeutic needs. Our expert team specializes in process development, leveraging innovative technology and extensive industry knowledge to provide clients with tailored solutions that exceed expectations. GMVC will be the ideal partner for scientists and healthcare professionals seeking reliable and efficient viral vector production services.
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