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Anti-MAO-A monoclonal antibody
Pre-made anti-MAO-A monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research
Go to MAO-A/MAOA products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-IP0006-Ab-1/ GM-Tg-hg-IP0006-Ab-2 | Anti-Human MAO-A/MAOA monoclonal antibody | Human |
| GM-Tg-rg-IP0006-Ab-1/ GM-Tg-rg-IP0006-Ab-2 | Anti-Rat MAO-A/MAOA monoclonal antibody | Rat |
| GM-Tg-mg-IP0006-Ab-1/ GM-Tg-mg-IP0006-Ab-2 | Anti-Mouse MAO-A/MAOA monoclonal antibody | Mouse |
| GM-Tg-cynog-IP0006-Ab-1/ GM-Tg-cynog-IP0006-Ab-2 | Anti-Cynomolgus/ Rhesus macaque MAO-A/MAOA monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-IP0006-Ab-1/ GM-Tg-felg-IP0006-Ab-2 | Anti-Feline MAO-A/MAOA monoclonal antibody | Feline |
| GM-Tg-cang-IP0006-Ab-1/ GM-Tg-cang-IP0006-Ab-2 | Anti-Canine MAO-A/MAOA monoclonal antibody | Canine |
| GM-Tg-bovg-IP0006-Ab-1/ GM-Tg-bovg-IP0006-Ab-2 | Anti-Bovine MAO-A/MAOA monoclonal antibody | Bovine |
| GM-Tg-equg-IP0006-Ab-1/ GM-Tg-equg-IP0006-Ab-2 | Anti-Equine MAO-A/MAOA monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-IP0006-Ab-1/ GM-Tg-hg-IP0006-Ab-2; GM-Tg-rg-IP0006-Ab-1/ GM-Tg-rg-IP0006-Ab-2; GM-Tg-mg-IP0006-Ab-1/ GM-Tg-mg-IP0006-Ab-2; GM-Tg-cynog-IP0006-Ab-1/ GM-Tg-cynog-IP0006-Ab-2; GM-Tg-felg-IP0006-Ab-1/ GM-Tg-felg-IP0006-Ab-2; GM-Tg-cang-IP0006-Ab-1/ GM-Tg-cang-IP0006-Ab-2; GM-Tg-bovg-IP0006-Ab-1/ GM-Tg-bovg-IP0006-Ab-2; GM-Tg-equg-IP0006-Ab-1/ GM-Tg-equg-IP0006-Ab-2 |
| Products Name | Anti-MAO-A/MAOA monoclonal antibody |
| Format | mab |
| Target Name | MAO-A |
| Protein Sub-location | Introcelluar Protein |
| Category of antibody | Therapeutics Target antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected. |
| Tag | Fc |
| Products description | Pre-made anti-MAO-A monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation | Lyophilized from sterile PBS, PH 7.4 |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | GM-Tg-g-IP0006-Ag-1 | Recombinant multi-species AOFA/ MAO-A/ MAOA protein |
| ORF Viral Vector | vGMLP002137 | human MAOA Lentivirus particle |
| ORF Viral Vector | pGMLP002137 | human MAOA Lentivirus plasmid |
| ORF Viral Vector | pGMLPm004342 | mouse Maoa Lentivirus plasmid |
| ORF Viral Vector | vGMLPm004342 | mouse Maoa Lentivirus particle |
Target information
| Target ID | GM-IP0006 |
| Target Name | MAO-A |
| Gene ID | 4128,17161,29253,708371,403450,101091848,281293,100033867 |
| Gene Symbol and Synonyms | 1110061B18Rik,BRNRS,Mao,MAO-A,MAOA |
| Uniprot Accession | P21397,P21396,P58027,P21398,Q5NU32 |
| Uniprot Entry Name | AOFA_HUMAN,AOFA_RAT,AOFA_CANLF,AOFA_BOVIN,AOFA_HORSE |
| Protein Sub-location | Introcelluar Protein |
| Category | Therapeutics Target |
| Disease | N/A |
| Gene Ensembl | ENSG00000189221 |
| Target Classification | N/A |
The target: MAO-A, gene name: MAOA, also named as BRNRS, MAO-A. This gene is one of two neighboring gene family members that encode mitochondrial enzymes which catalyze the oxidative deamination of amines, such as dopamine, norepinephrine, and serotonin. Mutation of this gene results in Brunner syndrome. This gene has also been associated with a variety of other psychiatric disorders, including antisocial behavior. Alternatively spliced transcript variants encoding multiple isoforms have been observed. [provided by RefSeq, Jul 2012].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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