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Anti-SCD monoclonal antibody
Pre-made anti-SCD monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research
Go to SCD/SCD products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-IP0008-Ab-1/ GM-Tg-hg-IP0008-Ab-2 | Anti-Human SCD monoclonal antibody | Human |
| GM-Tg-rg-IP0008-Ab-1/ GM-Tg-rg-IP0008-Ab-2 | Anti-Rat SCD monoclonal antibody | Rat |
| GM-Tg-mg-IP0008-Ab-1/ GM-Tg-mg-IP0008-Ab-2 | Anti-Mouse SCD monoclonal antibody | Mouse |
| GM-Tg-cynog-IP0008-Ab-1/ GM-Tg-cynog-IP0008-Ab-2 | Anti-Cynomolgus/ Rhesus macaque SCD monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-IP0008-Ab-1/ GM-Tg-felg-IP0008-Ab-2 | Anti-Feline SCD monoclonal antibody | Feline |
| GM-Tg-cang-IP0008-Ab-1/ GM-Tg-cang-IP0008-Ab-2 | Anti-Canine SCD monoclonal antibody | Canine |
| GM-Tg-bovg-IP0008-Ab-1/ GM-Tg-bovg-IP0008-Ab-2 | Anti-Bovine SCD monoclonal antibody | Bovine |
| GM-Tg-equg-IP0008-Ab-1/ GM-Tg-equg-IP0008-Ab-2 | Anti-Equine SCD monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-IP0008-Ab-1/ GM-Tg-hg-IP0008-Ab-2; GM-Tg-rg-IP0008-Ab-1/ GM-Tg-rg-IP0008-Ab-2; GM-Tg-mg-IP0008-Ab-1/ GM-Tg-mg-IP0008-Ab-2; GM-Tg-cynog-IP0008-Ab-1/ GM-Tg-cynog-IP0008-Ab-2; GM-Tg-felg-IP0008-Ab-1/ GM-Tg-felg-IP0008-Ab-2; GM-Tg-cang-IP0008-Ab-1/ GM-Tg-cang-IP0008-Ab-2; GM-Tg-bovg-IP0008-Ab-1/ GM-Tg-bovg-IP0008-Ab-2; GM-Tg-equg-IP0008-Ab-1/ GM-Tg-equg-IP0008-Ab-2 |
| Products Name | Anti-SCD monoclonal antibody |
| Format | mab |
| Target Name | SCD |
| Protein Sub-location | Introcelluar Protein |
| Category of antibody | Therapeutics Target antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected. |
| Tag | Fc |
| Products description | Pre-made anti-SCD monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | GM-Tg-g-IP0008-Ag-1 | Recombinant multi-species SCD/ FADS5/ MSTP0081 protein |
| ORF Viral Vector | pGMLP003589 | human SCD Lentivirus plasmid |
| ORF Viral Vector | vGMLP003589 | human SCD Lentivirus particle |
| ORF Viral Vector | pGMLV000812 | water buffalo SCD Lentivirus plasmid |
| ORF Viral Vector | pGMAD000389 | cattle SCD Adenovirus plasmid |
| ORF Viral Vector | pGMAAV000326 | Norway rat Scd AAV plasmid |
| ORF Viral Vector | vGMLV000812 | water buffalo SCD Lentivirus particle |
| ORF Viral Vector | vGMAD000389 | cattle SCD Adenovirus particle |
| ORF Viral Vector | vGMAAV000326 | Norway rat Scd AAV particle |
| ORF Viral Vector | pGMLPm004374 | mouse Scd1 Lentivirus plasmid |
| ORF Viral Vector | vGMLPm004374 | mouse Scd1 Lentivirus particle |
Target information
| Target ID | GM-IP0008 |
| Target Name | SCD |
| Gene ID | 6319,710155,486839,101091403,280924,100060485 |
| Gene Symbol and Synonyms | FADS5,hSCD1,MSTP008,SCD,SCD1,SCDOS |
| Uniprot Accession | O00767,Q9TT94 |
| Uniprot Entry Name | SCD_HUMAN,SCD_BOVIN |
| Protein Sub-location | Introcelluar Protein |
| Category | Therapeutics Target |
| Disease | Prostate Cancer |
| Gene Ensembl | ENSG00000099194 |
| Target Classification | N/A |
The target: SCD, gene name: SCD, also named as FADS5, MSTP0081, SCDOS, hSCD1, SCD. This gene encodes an enzyme involved in fatty acid biosynthesis, primarily the synthesis of oleic acid. The protein belongs to the fatty acid desaturase family and is an integral membrane protein located in the endoplasmic reticulum. Transcripts of approximately 3.9 and 5.2 kb, differing only by alternative polyadenlyation signals, have been detected. A gene encoding a similar enzyme is located on chromosome 4 and a pseudogene of this gene is located on chromosome 17. [provided by RefSeq, Sep 2015].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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