Anti-OPRS1 monoclonal antibody

Pre-made anti-OPRS1 monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research

Target products collectionGo to OPRS1/SIGMAR1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-IP0013-Ab-1/ GM-Tg-hg-IP0013-Ab-2Anti-Human OPRS1/SIGMAR1 monoclonal antibodyHuman
GM-Tg-rg-IP0013-Ab-1/ GM-Tg-rg-IP0013-Ab-2Anti-Rat OPRS1/SIGMAR1 monoclonal antibodyRat
GM-Tg-mg-IP0013-Ab-1/ GM-Tg-mg-IP0013-Ab-2Anti-Mouse OPRS1/SIGMAR1 monoclonal antibodyMouse
GM-Tg-cynog-IP0013-Ab-1/ GM-Tg-cynog-IP0013-Ab-2Anti-Cynomolgus/ Rhesus macaque OPRS1/SIGMAR1 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-IP0013-Ab-1/ GM-Tg-felg-IP0013-Ab-2Anti-Feline OPRS1/SIGMAR1 monoclonal antibodyFeline
GM-Tg-cang-IP0013-Ab-1/ GM-Tg-cang-IP0013-Ab-2Anti-Canine OPRS1/SIGMAR1 monoclonal antibodyCanine
GM-Tg-bovg-IP0013-Ab-1/ GM-Tg-bovg-IP0013-Ab-2Anti-Bovine OPRS1/SIGMAR1 monoclonal antibodyBovine
GM-Tg-equg-IP0013-Ab-1/ GM-Tg-equg-IP0013-Ab-2Anti-Equine OPRS1/SIGMAR1 monoclonal antibodyEquine

Size: 1mg | 10mg | 100mg

Product Description

Catalog No.GM-Tg-hg-IP0013-Ab-1/ GM-Tg-hg-IP0013-Ab-2; GM-Tg-rg-IP0013-Ab-1/ GM-Tg-rg-IP0013-Ab-2;
GM-Tg-mg-IP0013-Ab-1/ GM-Tg-mg-IP0013-Ab-2; GM-Tg-cynog-IP0013-Ab-1/ GM-Tg-cynog-IP0013-Ab-2;
GM-Tg-felg-IP0013-Ab-1/ GM-Tg-felg-IP0013-Ab-2; GM-Tg-cang-IP0013-Ab-1/ GM-Tg-cang-IP0013-Ab-2;
GM-Tg-bovg-IP0013-Ab-1/ GM-Tg-bovg-IP0013-Ab-2; GM-Tg-equg-IP0013-Ab-1/ GM-Tg-equg-IP0013-Ab-2
Products NameAnti-OPRS1/SIGMAR1 monoclonal antibody
Target NameOPRS1
Protein Sub-locationIntrocelluar Protein
Category of antibodyTherapeutics Target antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected.
Products descriptionPre-made anti-OPRS1 monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation Lyophilized from sterile PBS, PH 7.4
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


    Data / case study

    Click to get more Data / Case study about the product.

    Associated products

    CategoryCat No.Products Name
    Target AntigenGM-Tg-g-IP0013-Ag-1Recombinant multi-species SGMR1/ OPRS1/ SIGMAR1 protein
    ORF Viral VectorvGMLV000203human SIGMAR1 Lentivirus particle
    ORF Viral VectorpGMLV000203human SIGMAR1 Lentivirus plasmid
    ORF Viral VectorpGMLPm003847mouse Sigmar1 Lentivirus plasmid
    ORF Viral VectorvGMLPm003847mouse Sigmar1 Lentivirus particle

    Target information

    Target IDGM-IP0013
    Target NameOPRS1
    Gene ID10280,18391,29336,700469,481587,101084912,538903,100068507
    Gene Symbol and SynonymsALS16,DSMA2,hSigmaR1,OPRS1,SIG-1R,Sig1R,sigma1R,SIGMAR1,SR-BP,SR-BP1,SRBP
    Uniprot AccessionQ99720,Q9R0C9,Q58DH7
    Protein Sub-locationIntrocelluar Protein
    CategoryTherapeutics Target
    Gene EnsemblENSG00000147955
    Target ClassificationN/A

    The target: OPRS1, gene name: SIGMAR1, also named as ALS16, DSMA2, OPRS1, SIG-1R, SR-BP, SR-BP1, SRBP, hSigmaR1, sigma1R. This gene encodes a receptor protein that interacts with a variety of psychotomimetic drugs, including cocaine and amphetamines. The receptor is believed to play an important role in the cellular functions of various tissues associated with the endocrine, immune, and nervous systems. As indicated by its previous name, opioid receptor sigma 1 (OPRS1), the product of this gene was erroneously thought to function as an opioid receptor; it is now thought to be a non-opioid receptor. Mutations in this gene has been associated with juvenile amyotrophic lateral sclerosis 16. Alternative splicing of this gene results in transcript variants encoding distinct isoforms. [provided by RefSeq, Aug 2013].

    About Gmab


    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.